The startup develops non-invasive medical devices that utilize localized cooling technologies to deliver therapeutic treatments without skin penetration. This approach provides healthcare providers with a safe and effective method for managing pain and inflammation in patients.

Centese develops Thoraguard, an automated chest tube management system that utilizes digital monitoring to provide real-time data on air leak rates and drainage volumes. This technology addresses the unreliability of current surgical drainage systems, which can lead to complications, extended hospital stays, and increased healthcare costs.

CereVu Medical has developed a real-time objective pain assessment system that utilizes proprietary algorithms to quantitatively measure pain levels and evaluate treatment effectiveness. This technology addresses the challenge of inadequate pain management by providing physicians with precise data to inform timely and appropriate interventions.

Cooler Heads has developed Amma™, a portable scalp cooling system that lowers scalp temperature during chemotherapy to reduce hair loss by limiting the absorption of chemotherapy drugs in hair follicles. This FDA-cleared device allows patients to self-administer treatment anywhere in the infusion center, providing a practical solution for maintaining their identity and mental well-being during cancer treatment.

Eirion Therapeutics is a clinical-stage biopharmaceutical company developing next-generation prescription products that target specific disease pathways using advanced drug delivery systems. Their focus is on improving patient outcomes by enhancing the efficacy and safety profiles of existing therapies.

LimiFlex has developed the Dynamic Sagittal Tether™, a minimally invasive stabilization device designed for patients with grade I degenerative spondylolisthesis and spinal stenosis. This system preserves natural spinal motion while providing necessary stability post-decompression, offering a viable alternative to traditional spinal fusion, which is often invasive and carries significant risks.

The startup offers an API that utilizes machine learning algorithms for precise data extraction from various document formats. This technology addresses the challenge of manual data entry errors and inefficiencies, enabling businesses to automate data processing with high accuracy.

Kin transforms existing web stores into fully functional mobile applications that maintain functional parity with the web presence. The platform enables brands to build deeper customer relationships through personalized experiences and unlimited push notifications. This focus on mobile engagement drives increased customer lifetime value and higher repeat purchase rates for e-commerce businesses.

Koya Medical develops the Dayspring® active compression system, a portable device designed to provide dynamic compression therapy for patients with lymphedema and venous diseases. This technology enhances mobility while delivering effective treatment, addressing the limitations of traditional compression methods.

Liberate Medical develops the VentFree Respiratory Muscle Stimulator, a non-invasive device that uses electrical stimulation to contract expiratory muscles during mechanical ventilation. This therapy begins on day one of ventilation to maintain muscle activity and potentially reduce respiratory muscle atrophy. The intended outcome is to decrease the duration patients require mechanical ventilation support.

Podimetrics provides a SmartMat™ that monitors foot temperature in patients with advanced diabetes to detect early signs of inflammation, enabling timely clinical intervention. This technology aims to prevent diabetic foot ulcers and amputations, significantly reducing healthcare costs and improving patient mobility and quality of life.

SecondWave Systems is developing a noninvasive, wearable ultrasound stimulation platform that utilizes low-intensity focused ultrasound (LiFU) to modulate neural and cellular pathways for the treatment of conditions such as inflammation and pain. This technology offers patients an alternative to costly medications with side effects, enabling in-home self-administration and reducing the need for frequent medical visits.