Akadeum develops the Alerion™ Microbubble Cell Separation System, which utilizes microbubble technology for negative selection and cell depletion workflows to isolate healthier cells from biological samples. This system enhances cell viability and recovery while increasing scalability, addressing the need for more efficient and effective cell therapy manufacturing processes.

Allay Therapeutics develops targeted analgesic formulations specifically designed for post-surgical pain management, utilizing a proprietary delivery system to enhance absorption and efficacy. Their products aim to reduce opioid reliance and improve patient recovery outcomes following surgical procedures.

This startup provides a clinical performance analytics platform that uses data science to deliver insights for healthcare providers. It helps integrate, store, and analyze cloud-based clinical data to improve patient outcomes, optimize financial performance, and measure the real-world effectiveness of treatments and medical technologies.

AtaCor Medical develops extravascular cardiac pacing and defibrillation lead systems that eliminate the need for transvenous access, reducing the risks and complications associated with traditional methods. Their technology enables reliable temporary pacing and defibrillation while allowing for safe patient ambulation post-procedure.

Avation Medical has developed the Vivally® System, a wearable physiologic closed-loop neuromodulation device that utilizes transcutaneous tibial nerve stimulation to treat overactive bladder (OAB) symptoms at home. This FDA-cleared system allows patients to manage urinary urgency and urge urinary incontinence with just 30 minutes of use, one to three times a week, while tracking their progress through a mobile application.

Boomerang runs a clinical trial for ulcerative colitis that evaluates a non‑drug neurostimulation device aimed at reducing bowel urgency. Eligible patients complete an online survey to determine qualification, and participants receive medical support and possible travel stipends during the study. The company monetizes through research contracts and funding tied to the investigational device trial.

BrightSpec offers the spectraMRR™ platform, which uses Molecular Rotational Resonance (MRR) spectroscopy to directly identify and quantify small‑molecule structures from liquids, gases, or headspace without chromatography, derivatization, or extensive sample preparation. The system combines ultra‑high‑resolution rotational fingerprinting with quantum‑simulation software and SpectrAline™ sample‑introduction cartridges to deliver rapid, automated, and highly accurate analysis for pharmaceutical, chemical, food safety, and consumer‑goods applications.

ConcertoCare provides a tech‑enabled, interdisciplinary in‑home care model that creates personalized care plans integrating medical, medication, safety, and social services. By coordinating physicians, nurses, pharmacists, and community caregivers with a patient’s existing doctors and benefits, the platform delivers clinical visits, medication management, transportation, nutrition assistance, and advanced care planning to improve well‑being and reduce hospitalizations for seniors and high‑needs adults.

Convergent Dental offers the Solea® All‑Tissue Laser, an FDA‑cleared 9.3 µm CO₂ laser that vaporizes enamel and cuts hard and soft oral tissues without drills, injections, or sutures. The system enables anesthesia‑free, blood‑free procedures across restorative, periodontal, implant and cosmetic dentistry, reducing chair time and postoperative discomfort. Integrated safety controls, modular accessories and cloud‑based training support rapid adoption and consistent clinical outcomes.

Enumera Molecular provides the EnumeraPlex™ platform to simplify complex, high-analyte molecular testing for clinical use. This technology enables simplified, cost-effective workflows for liquid biopsy and broad clinical genomic applications in any laboratory. The platform delivers high-performance pan-omic detection without PCR bias and eliminates the need for complex bioinformatics analysis.

Francis Medical is developing the Vanquish® Water Vapor Ablation System, which utilizes thermal energy from sterile water vapor to ablate cancerous prostate tissue through a minimally invasive transurethral procedure. This technology aims to reduce the severe side effects associated with traditional prostate cancer treatments, allowing patients to return to their normal activities the day after the procedure.

Heal is a nonprofit ecommerce platform that utilizes experience-based peer support to help individuals with mental illness reconnect with their passions through creative expression. By empowering emerging artists to showcase their work, Heal reinvests 100% of its profits into community-building initiatives that foster meaningful connections.

JUMPCODE offers CRISPR-mediated rRNA depletion kits, including DepleteX™ and CRISPRclean®, that enhance next-generation sequencing (NGS) workflows by removing uninformative nucleic acids. This technology improves sensitivity and data quality across various genomic applications, including single-cell analysis and microbiome characterization.

Koya Medical develops the Dayspring® active compression system, a portable device designed to provide dynamic compression therapy for patients with lymphedema and venous diseases. This technology enhances mobility while delivering effective treatment, addressing the limitations of traditional compression methods.

Motif Neurotech develops bioelectronic therapeutic Brain Computer Interface (BCI) devices for mental health applications. Their technology measures and regulates specific brain networks to alleviate symptoms of treatment-resistant depression. The implantable system is designed for outpatient procedures, allowing patients to manage their condition from home.

Navv Systems offers real-time location services (RTLS) for indoor navigation and asset tracking in hospitals and health systems. This technology improves patient flow and equipment management, leading to enhanced operational efficiency and better patient care.

Orasis Pharmaceuticals develops QLOSI™, an ophthalmic eye drop formulation designed to treat presbyopia, a condition that causes blurred near vision due to the aging of the eye's crystalline lens. This product aims to enhance visual acuity for over 128 million people in the U.S. affected by this progressive condition.

Provides an API-driven authorization service that enables developers to implement role-based (RBAC), relationship-based (ReBAC), and attribute-based (ABAC) access control without overhauling existing application architectures. By generating SQL filters and authorizing locally against existing databases, it reduces integration time, eliminates syncing issues, and supports high-performance, scalable permission management across cloud, hybrid, and on-prem environments.

The startup manufactures biopharmaceuticals with automated systems and consumables designed for laboratory and GMP environments, implementing continuous processing to enhance operational efficiency. Their solutions enable clients to achieve higher productivity, reduced capital expenditures, and minimized facility space requirements.

Re is an on‑chain reinsurance protocol that tokenizes real reinsurance treaties, issuing fully collateralized tokens backed by verified insurance premiums. The platform provides institutional investors and insurers with regulated, transparent access to the $800B+ reinsurance market, delivering 8‑16% annual yields that are largely uncorrelated with traditional assets while maintaining defined risk limits and underwriting discipline.

Reprieve Cardiovascular offers the Reprieve System, a personalized intelligent decongestion management solution that utilizes real-time patient data to optimize diuretic therapy for acute decompensated heart failure patients. This system addresses the challenge of fluid overload, which accounts for 83% of heart failure hospitalizations, by providing physicians with enhanced visibility and control over treatment decisions.

Ro operates a telehealth platform that provides online clinics for weight loss, sexual health, hair restoration, and fertility management using clinically proven treatments and prescription medications. The service eliminates the need for insurance and offers free, discreet shipping, making healthcare accessible and convenient for over 2 million members.

SonarMD utilizes a digital monitoring platform to track gastrointestinal health in patients with chronic conditions, enabling early detection of clinical decline through personalized health assessments and a proprietary scoring algorithm. This proactive approach reduces hospitalizations by 50% and lowers annual healthcare costs by over $3,000 per patient.

Strata Oncology develops predictive biomarkers for antibody-drug conjugates (ADCs) and immunotherapy, utilizing a proprietary algorithm that combines tumor mutation burden and protein expression metrics. This technology enables oncologists to identify the most effective treatment options for patients, improving therapeutic outcomes in precision oncology.