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406 Ventures
Boston, United States
.406 Ventures focuses on early‑stage seed and Series A investments in three core domains: healthcare, data + AI, and cybersecurity. Leveraging deep domain expertise, extensive networks, and a partnership‑first approach,...
Portfolio
79+
Employees
100+
Founded
2005
AUM
N/A
Investment focus
Stages
Seed → Series A
Industries
Artificial IntelligenceData & AnalyticsCybersecurityEnterprise Software
Geographic scope
North America
Sources
406 Ventures
.406 Ventures focuses on early‑stage seed and Series A investments in three core domains: healthcare, data + AI, and cybersecurity. Leveraging deep domain expertise, extensive networks, and a partnership‑first approach, the firm backs founders building technology‑enabled health solutions, AI infrastructure and applications, and security innovations, providing both capital and strategic support to accelerate growth and create category‑defining companies.
Portfolio
79+
Employees
100+
Founded
2005
AUM
N/A
Stages
Seed → Series A
Industries
Artificial IntelligenceData & AnalyticsCybersecurityEnterprise SoftwareHealthcare Technology
Geographic scope
North America
Sources
Showing 24 of 68 matched portfolio companies
Provides a data management platform for healthcare payers that consolidates and normalizes diverse data sources into interoperable, 360-degree patient records. This enables compliance with CMS mandates, improves risk adjustment accuracy, and reduces costs by delivering timely, usable data for clinical, operational, and reporting needs.
Funding: $100.8M
Rough estimate of the amount of funding raised
MultiPlan
MultiPlan
Funding: $100.8M
Rough estimate of the amount of funding raised
AbleTo provides evidence‑based, CBT‑focused mental health programs through secure video sessions with licensed therapists and certified coaches. The platform offers flexible scheduling, integrates with health‑plan coverage to eliminate out‑of‑pocket costs for members, and combines live therapy with guided self‑care exercises and progress tracking to address anxiety, depression, stress, and related conditions.
Optum Ventures
Air is a visual workspace that centralizes the collection, approval, and sharing of creative assets, streamlining the creative operations process for teams. By replacing traditional cloud storage solutions, it eliminates the inefficiencies of file management and feedback loops, saving users significant time and improving collaboration.
Funding: $69.2M
Rough estimate of the amount of funding raised
Funding: $69.2M
Rough estimate of the amount of funding raised
AristaMD provides SpecialtyCare360, a platform that connects primary‑care providers with a network of virtual specialists in areas such as cardiology, rheumatology, and musculoskeletal care. The service streamlines referrals, delivers rapid treatment plans, and includes care navigation, patient coaching, and performance analytics to improve outcomes while lowering costs for health systems and large provider networks.
Funding: $16.5M
Rough estimate of the amount of funding raised
Funding: $16.5M
Rough estimate of the amount of funding raised
Ascellus offers a HIPAA‑compliant virtual health platform that delivers work‑focused cognitive behavioral therapy to injured workers in workers’ compensation cases. Certified clinicians provide rapid telehealth assessments and ongoing treatment, while case coordinators and quality‑assurance advisors generate clinical reports and integrate progress data directly with insurers, TPAs and claims adjusters to support functional recovery and claim resolution.
50+
1K+Approximate amount of employees
Funding: $453.8K
Rough estimate of the amount of funding raised
Funding: $453.8K
Rough estimate of the amount of funding raised
BedR India operates a zero-brokerage marketplace for booking verified PG accommodations, hostels, and co-living spaces across Mumbai. The platform streamlines the rental process by offering instant booking, secure digital agreements, and transparent pricing with only a small service fee. Additionally, BedR offers a property management platform for owners to automate rent collection, manage tenants, and track occupancy analytics.
Bend enhances spend data accuracy by providing precise emissions estimates for scope 3 goods and services, utilizing a robust matching system that aligns supplier and line-item data with vetted emissions factors. This enables companies to generate compliant, audit-ready GHG emission calculations and identify high-impact decarbonization opportunities.
Funding: $2.5M
Rough estimate of the amount of funding raised
Funding: $2.5M
Rough estimate of the amount of funding raised
Better Life Partners offers medical and behavioral healthcare services, including medication-assisted treatment and therapy, to support individuals recovering from addiction. Their team provides accessible care through in-person and virtual options, ensuring timely support tailored to each person's needs.
Funding: $33.9M
Rough estimate of the amount of funding raised
Funding: $33.9M
Rough estimate of the amount of funding raised
Bluebird Kids Health provides 24/7 pediatric primary care through a value-based model that integrates physical, mental, and emotional health services tailored to the needs of families in underserved communities. By accepting most insurances, including Medicaid, the startup ensures accessible, high-quality healthcare that aims to improve health outcomes and reduce medical costs for children.
Funding: $25.0M
Rough estimate of the amount of funding raised
Funding: $25.0M
Rough estimate of the amount of funding raised
Bobsled provides a data product platform designed to transform data into AI-ready assets and conversational experiences. The platform enables secure data sharing across various environments via a data access network with zero-copy capabilities. It supports agentic analytics and workflows by integrating context and semantic models for accurate, automated data reasoning.
Funding: $17.0M
Rough estimate of the amount of funding raised
GreycroftMadrona
GreycroftMadrona
Funding: $17.0M
Rough estimate of the amount of funding raised
Carbon provides a digital banking platform that offers instant loans, savings accounts with competitive interest rates, and payment solutions without the need for collateral or guarantors. By simplifying access to credit and financial management tools, Carbon addresses the lack of affordable financial services for individuals in Nigeria and beyond.
Funding: $5.0M
Rough estimate of the amount of funding raised
Lendable
Lendable
Funding: $5.0M
Rough estimate of the amount of funding raised
ChaosSearch provides a data platform that integrates with Databricks to enable scalable log analytics using native Elasticsearch query capabilities. The solution consolidates log and event data in a unified data lake, offering unlimited retention and reducing costs by 50-80% while eliminating the need for data movement or transformation.
Funding: $56.0M
Rough estimate of the amount of funding raised
Moore CapitalStripes
Moore CapitalStripes
Funding: $56.0M
Rough estimate of the amount of funding raised
Closedloop is an AI‑augmented platform that unifies requirements, implementation plans, design prototypes, and code changes in a single shared system. It links these artifacts with structured context, provides automated validation against original intents, and offers real‑time visibility to replace status meetings, helping software teams maintain control and reduce risk throughout the development lifecycle.
Funding: $25.0K
Rough estimate of the amount of funding raised
Funding: $25.0K
Rough estimate of the amount of funding raised
Compass provides a commission automation platform that streamlines the sales compensation process through real-time data integration and a no-code plan builder, ensuring accurate and timely payouts. By eliminating manual calculations and reducing processing time by 95%, Compass enhances sales productivity and minimizes operational errors in incentive management.
Cortica provides personalized neurological therapies, including Applied Behavioral Analysis (ABA), speech, and occupational therapy, for children with autism and other developmental differences. The startup offers a coordinated, multidisciplinary approach to care, enabling measurable improvements in communication, social skills, and emotional regulation through evidence-based treatment plans.
Funding: $80.0M
Rough estimate of the amount of funding raised
Morgan HealthNexus NeuroTech
Morgan HealthNexus NeuroTech
Funding: $80.0M
Rough estimate of the amount of funding raised
Corvus Link is a software platform that enables business users to identify and mitigate operational risks through data-driven insights and real-time analytics. By enhancing organizational resilience, it helps companies adapt to constant change and improve decision-making processes.
Diana Health provides personalized telehealth services for maternity care and women's health, utilizing a collaborative care model that integrates physical, mental, and social well-being. The platform addresses the lack of accessible, respectful, and comprehensive healthcare options for women at all stages of life, offering same and next-day appointments to enhance convenience and responsiveness.
Funding: $46.2M
Rough estimate of the amount of funding raised
Norwest Venture Partners
Norwest Venture Partners
Funding: $46.2M
Rough estimate of the amount of funding raised
Edgewise Networks employs advanced micro-segmentation and behavioral analytics to prevent unauthorized access and lateral movement within applications. This approach mitigates the risk of application compromise and limits the impact of cyber attacks on network infrastructure.
Founded 2016700+
Funding: $11.0M
Rough estimate of the amount of funding raised
.406 VenturesAccomplice
.406 VenturesAccomplice
Funding: $11.0M
Rough estimate of the amount of funding raised
Equip Health offers a virtual, evidence-based treatment program for eating disorders, utilizing a multidisciplinary care team that includes therapists, dietitians, and peer mentors to provide comprehensive support. The platform addresses the high prevalence of eating disorders by delivering accessible, family-centered care that promotes sustainable recovery from the comfort of home.
Funding: $109.7M
Rough estimate of the amount of funding raised
Funding: $109.7M
Rough estimate of the amount of funding raised
FamilyWell provides integrated perinatal mental health services through a collaborative care model, enabling obstetric clinics to offer billable, tech-enabled support for pregnant and postpartum patients. This approach addresses the high prevalence of postpartum depression and the associated risks of suicide and overdose, improving access to timely mental health care and reducing health disparities.
Funding: $4.3M
Rough estimate of the amount of funding raised
.406 Ventures
.406 Ventures
Funding: $4.3M
Rough estimate of the amount of funding raised
Dig is a social video intelligence platform that provides comprehensive global coverage of social video content. It decodes in-video elements like spoken words and visuals to surface emerging narratives and track brand perception at scale. This allows brands to proactively manage reputation, extract consumer insights, and optimize content strategy through real-time reporting and alerts.
Funding: $8.0M
Rough estimate of the amount of funding raised
New Era Capital Partners
New Era Capital Partners
Funding: $8.0M
Rough estimate of the amount of funding raised
Heal is a nonprofit ecommerce platform that utilizes experience-based peer support to help individuals with mental illness reconnect with their passions through creative expression. By empowering emerging artists to showcase their work, Heal reinvests 100% of its profits into community-building initiatives that foster meaningful connections.
Heartbeat Health operates a telemedicine platform that utilizes real-time clinical data and device connectivity to provide remote cardiovascular care, including same-day diagnostic reads and virtual consultations with cardiologists. This platform addresses the challenge of accessing high-quality heart care by enabling patients to monitor their heart health and receive timely treatment from the comfort of their homes.
Funding: $66.5M
Rough estimate of the amount of funding raised
Cressey & Company
Cressey & Company
Funding: $66.5M
Rough estimate of the amount of funding raised
hOS develops AI-driven technologies designed to maximize prosperity and minimize suffering by addressing real-world challenges through scalable solutions. The company focuses on creating systems that enhance human decision-making and operational efficiency across various sectors.
Funding: $12.8M
Rough estimate of the amount of funding raised
Funding: $12.8M
Rough estimate of the amount of funding raised
Showing 11 of 11 unmatched portfolio companies
ThingMagic
No website provided
We don't have a full profile for this company yet.
Terbium Labs
No website provided
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Pwnie Express
No website provided
We don't have a full profile for this company yet.
Vaultive
No website provided
We don't have a full profile for this company yet.
Veracode
No website provided
We don't have a full profile for this company yet.
Wellaware
No website provided
We don't have a full profile for this company yet.
Optaros
No website provided
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Threat Stack
No website provided
We don't have a full profile for this company yet.
Threatgrid
No website provided
We don't have a full profile for this company yet.