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First Star Ventures
Cambridge, United States
We invest in visionary technical founders building frontier computing technologies such as AI/ML, decentralization, edge computing, and tech‑bio solutions. Our focus is on early‑stage deep‑tech companies where we can pro...
Portfolio
38+
Employees
3+
Founded
2014
AUM
≈ $40.0M
Investment focus
Stages
Pre-Seed → Series A
Industries
Artificial IntelligenceData & AnalyticsBiotechnologyBlockchain & Cryptocurrency
Geographic scope
United States
Fund details
Funds
Fund III
Vintage 2022 • $40.0M
Sources
First Star Ventures
We invest in visionary technical founders building frontier computing technologies such as AI/ML, decentralization, edge computing, and tech‑bio solutions. Our focus is on early‑stage deep‑tech companies where we can provide capital, operational expertise, and a strategic network to help them scale quickly.
Portfolio
38+
Employees
3+
Founded
2014
AUM
≈ $40.0M
Funds
Fund III · Vintage 2022 • $40.0M
Stages
Pre-Seed → Series A
Industries
Artificial IntelligenceData & AnalyticsBiotechnologyBlockchain & CryptocurrencyHealthcare Technology
Geographic scope
United States
Sources
Showing 24 of 34 matched portfolio companies
Bedrock Energy develops novel technology to make geothermal borehole fields affordable, fast, and space-efficient for real estate applications. This ground-source heat pump approach provides highly efficient and resilient HVAC solutions for buildings. The company offers end-to-end services, including design, fast drilling, and project management, to reduce long-term energy costs.
Funding: $20.5M
Rough estimate of the amount of funding raised
Titanium Ventures
Titanium Ventures
Funding: $20.5M
Rough estimate of the amount of funding raised
Blumen Systems provides data and automation solutions for infrastructure permitting and regulatory intelligence. The platform cross-references site plans with jurisdictional rules to flag potential delays and costs before they occur. This enables project teams to automate permitting workflows and accelerate the deployment of utility-scale infrastructure.
Funding: $6.4M
Rough estimate of the amount of funding raised
Funding: $6.4M
Rough estimate of the amount of funding raised
Brink provides a decentralized intents protocol that lets Web3 developers define desired outcomes—such as token swaps, recurring transfers, or conditional trades—through a JSON‑based DSL and REST API. The protocol routes these intents to a network of solvers that source liquidity, execute the actions, and cover gas costs, enabling gas‑free, single‑signature workflows across multiple chains. It also offers MEV‑resistant settlement and built‑in support for recurring and cross‑chain intents.
3+
100+Approximate amount of employees
EnPowered provides a platform that facilitates access to financing and incentives for energy efficiency and clean energy projects, enabling businesses to implement solutions like LED lighting, solar, and battery storage without upfront costs. This approach allows companies to achieve immediate energy cost savings and reduce their carbon footprint while navigating complex financing challenges.
Enzymit develops a cell-free bioproduction platform utilizing computational protein design and high-throughput testing to create novel enzymes for various industries, including biochemicals and health. This technology addresses the inefficiencies and high costs associated with traditional enzymatic manufacturing processes, enabling faster and more sustainable production.
Funding: $16.1M
Rough estimate of the amount of funding raised
Funding: $16.1M
Rough estimate of the amount of funding raised
Feature Labs develops tools and APIs that automate data science workflows and feature engineering processes. This technology reduces the time and expertise required to prepare data for machine learning, enabling teams to focus on model development and deployment.
Founded 2015
Fyto develops automated cropping systems that utilize the aquatic plant lemna to enhance nutrient management on farms while producing high-value agricultural products. This technology addresses nutrient pollution and resource inefficiencies in farming by enabling sustainable crop production with reduced land, water, and labor inputs.
Funding: $18.0M
Rough estimate of the amount of funding raised
Funding: $18.0M
Rough estimate of the amount of funding raised
Genialis develops AI models for precision oncology to improve drug efficacy and patient outcomes. The platform provides therapeutic intelligence and biomarker discovery to stratify patients and enhance clinical success rates. This approach aims to ensure that promising drug molecules successfully become life-saving medicines.
Funding: $13.0M
Rough estimate of the amount of funding raised
Debiopharm Innovation FundTaiwania Capital Management Corporation
Debiopharm Innovation FundTaiwania Capital Management Corporation
Funding: $13.0M
Rough estimate of the amount of funding raised
The startup develops cryptographically attested software that establishes trust and authenticity in digital interactions through a framework for secure identity verification and data sharing. This technology enables users to collaborate without compromising privacy or data integrity, addressing the critical issues of digital trust and security.
Funding: $800.0K
Rough estimate of the amount of funding raised
Funding: $800.0K
Rough estimate of the amount of funding raised
Infinite Analytics offers SherlockAI, a real‑time data platform that aggregates millions of global consumer behavior points at block‑level resolution. The service enriches individuals with addressable IDs and behavioral attributes, enabling precise audience segmentation, persona creation, and direct activation of campaigns across advertising platforms, while providing predictive insights such as a Quality of Life Index for regional market assessment.
Jellyfish is an Engineering Management Platform that integrates issue tracking and source control management data to provide actionable insights on team performance, resource allocation, and project timelines. It enables engineering leaders to enhance operational efficiency and predictability by measuring key metrics, thereby aligning engineering efforts with strategic business objectives.
Kanary Copilot automates online safety actions to protect users from doxxing and digital stalking through a privacy-focused application. The platform enables individuals to manage their digital identities securely and efficiently from their devices.
Funding: $895.0K
Rough estimate of the amount of funding raised
2048 Ventures
2048 Ventures
Funding: $895.0K
Rough estimate of the amount of funding raised
MotionHall provides a cloud‑based platform that builds a digital twin of the global biopharma ecosystem by aggregating patents, clinical trial, regulatory and market data. Its AI‑driven analytics and integrated consulting layer deliver valuation models, competitive gap analysis, and transaction scenario simulations for senior executives managing IP portfolios and M&A strategies. Users access insights via an interactive dashboard with collaborative tools and export capabilities.
First Star Ventures
Native Voice provides a software SDK that enables audio device manufacturers to integrate branded voice services directly into their products, allowing users to interact with brands hands-free. This technology addresses the need for seamless voice command capabilities in listening devices, enhancing user experience and accessibility without requiring users to access their phones.
Nomic develops the nELISA platform, a high-throughput proteomics technology that utilizes DNA nanotechnology to enable flexible multiplexing of protein profiling. This platform addresses the limitations of traditional immunoassays by providing rapid, precise quantification of over 200 cytokines, facilitating comprehensive analysis of the immune secretome.
Funding: $60.0M
Rough estimate of the amount of funding raised
Funding: $60.0M
Rough estimate of the amount of funding raised
Oculi develops Software-Defined Vision Sensors to enhance AI-driven applications at the edge. Their IntelliPixel technology optimizes efficiency and maintains data privacy for commercial and defense markets. This approach delivers high-performance Vision AI with low power consumption and reduced cost.
Funding: $2.1M
Rough estimate of the amount of funding raised
Funding: $2.1M
Rough estimate of the amount of funding raised
Oort is a decentralized cloud computing platform that utilizes a blockchain-based verification layer to integrate global resources for secure data storage and AI model training. By leveraging idle computing power from data centers and edge devices, Oort reduces costs by up to 80% while ensuring 100% privacy for all data services.
Funding: $24.8M
Rough estimate of the amount of funding raised
Hike VenturesRedbeard Ventures
Hike VenturesRedbeard Ventures
Funding: $24.8M
Rough estimate of the amount of funding raised
Parallel Wireless provides Open RAN solutions that are hardware-agnostic, enabling flexible and scalable wireless network deployments. The company focuses on delivering software-based platforms that simplify network evolution across various access technologies. This approach allows mobile operators to deploy cost-effective and resilient cellular infrastructure.
Plex provides a data‑first platform that indexes billions of structured biomedical data points—genomics, proteomics, clinical trials, and literature—into a queryable knowledge graph. Researchers can ask natural‑language scientific questions and receive evidence‑backed answers scored across seven dimensions with source traceability, along with chemical‑intelligence tools and secure integration of proprietary data. The system generates structured deliverables such as Target Evaluation Reports and Biomarker Panels to support data‑driven R&D decisions for pharmaceutical and biotech teams.
Plus One Robotics provides InductOne, a turnkey dual‑arm induction cell that uses AI‑powered vision and an adaptive gripper to automate parcel handling in fulfillment centers. The system delivers 2,200–3,300 picks per hour with 99 % accuracy, fits into space‑constrained areas, and includes integrated safety, real‑time exception handling, and performance analytics to boost throughput while lowering labor costs.
Funding: $53.4M
Rough estimate of the amount of funding raised
+ 13 Other investorsScale Venture Partners
+ 13 Other investorsScale Venture Partners
Funding: $53.4M
Rough estimate of the amount of funding raised
Resilinc provides an agentic AI platform that continuously monitors global events, supplier health, ESG, financial and regulatory data across multi‑tier supplier networks, delivering real‑time risk scores and revenue impact assessments. The AI agents automatically generate prescriptive mitigation actions—such as alternative sourcing or compliance steps—through a chat‑driven interface, enabling large enterprises to detect, prioritize, and resolve supply chain disruptions before they affect operations.
Vista Equity Partners
Robigo engineers microbes to create effective and environmentally friendly crop protectants, addressing the significant crop losses of 20-40% due to diseases despite the use of over 6 billion pounds of pesticides annually. By enhancing soil health and increasing farm productivity, Robigo's biomanufacturing solutions promote sustainable agricultural practices.
Funding: $11.5M
Rough estimate of the amount of funding raised
Congruent Ventures
Congruent Ventures
Funding: $11.5M
Rough estimate of the amount of funding raised
Salient provides AI-powered weather intelligence spanning one day to one year ahead using deep learning models trained on extensive climate data. This platform delivers superior accuracy for subseasonal-to-seasonal predictions by focusing on ocean and land-surface inertia. Enterprise clients across agriculture, energy, and finance utilize these actionable forecasts and industry analytics for improved planning and risk management.
Funding: $8.7M
Rough estimate of the amount of funding raised
Bill & Melinda Gates Foundation
Bill & Melinda Gates Foundation
Funding: $8.7M
Rough estimate of the amount of funding raised
The startup develops ocean data analysis software that utilizes autonomous underwater vehicles to gather real-time ocean conditions and forecasts. This technology provides marine stakeholders with critical data to enhance logistics and operational decisions, thereby mitigating risks to marine assets.
Funding: $6.3M
Rough estimate of the amount of funding raised
Funding: $6.3M
Rough estimate of the amount of funding raised
Showing 4 of 4 unmatched portfolio companies