Amplitude Vascular Systems has developed Pulse IVL™, an intravascular lithotripsy system that utilizes high-frequency pulsatile pressure waves to fracture arterial calcium and restore blood flow in patients with severely calcified arterial disease. This technology enhances deliverability and efficiency, providing healthcare providers with a reliable tool to improve patient outcomes in vascular treatments.

The startup develops pulsed electric technology that utilizes microbursts of energy delivered via catheter to disrupt cardiac cells. This approach enhances the efficacy of cardiac ablation treatments while minimizing unintended consequences associated with traditional methods.

Nectero Medical is developing the Nectero Endovascular Aneurysm Stabilization Treatment (Nectero EAST®) System, which delivers a proprietary mixture directly to mid-sized abdominal aortic aneurysms to stabilize their growth and reduce the risk of rupture. This treatment aims to minimize the need for major surgical interventions, allowing patients to maintain a normal lifespan without facing the complications associated with traditional endovascular repair or open surgery.

The startup manufactures treatment devices for dry eye disease that stimulate the trigeminal parasympathetic pathway to enhance tear film production. This technology enables healthcare professionals to effectively manage chronic dry eye conditions in patients.

Senseonics offers the Eversense implantable continuous glucose monitoring system, embedding a small sensor under the skin to provide real‑time glucose readings for up to 365 days (or 180 days) via a rechargeable Bluetooth transmitter and companion mobile app. The platform removes the need for daily sensor changes, minimizes adhesive‑related skin irritation, and delivers clinically calibrated data with HIPAA‑compliant cloud storage for clinician access.