3T Biosciences develops transformative T-cell receptor (TCR) therapeutics aimed at treating solid tumors and immune-mediated diseases in diverse patient populations. The company addresses the limitations of current immunotherapies by enhancing the specificity and efficacy of T-cell responses against cancer cells.

Ammobia develops Haber-Bosch 2.0 technology to produce ammonia at the lowest cost with significantly reduced energy consumption. This breakthrough enables cost-effective, on-site production of ammonia for use as fertilizer feedstock, a zero-carbon fuel, and a hydrogen carrier. The modular plant design allows dynamic operation aligned with variable renewable power sources, supporting decarbonization across multiple industries.

AtmosZero manufactures a modular electrified heat pump designed to produce industrial steam without burning fuels. This technology provides a drop-in solution for process heat applications in sectors like food and beverage, pharmaceuticals, and district heating. The system eliminates criteria pollutants and GHG emissions associated with traditional boiler operations.

Blue Energy manufactures and operates modular nuclear power plants, focusing on predictable cost and reliable timelines through centralized fabrication. They de-risk construction via fixed-price contracting, enabling project finance for new nuclear assets. The company sells dispatchable, baseload megawatts to industrial customers through long-term power purchase agreements.

Carbo Culture develops proprietary Carbolysis™ reactors that convert waste biomass into stable biochar, effectively sequestering carbon for centuries while generating renewable energy. This technology provides a scalable solution for carbon removal, addressing the urgent need to reduce atmospheric CO2 levels and combat climate change.

CarbonChain offers a cloud‑based carbon accounting platform that aggregates verified, asset‑level emissions data for over 11,000 commodity suppliers, aligned with the GHG Protocol and validated by SGS. The solution lets procurement, sales, and finance teams instantly benchmark suppliers, visualize carbon tariffs such as CBAM, and generate product carbon footprints through ERP, CTRM, Excel, or API integrations, helping them meet regulatory reporting, reduce carbon taxes, and secure better financing terms.

The startup develops a data conversion and storage platform that encodes digital information into deoxyribonucleic acid (DNA) format, providing a long-term archival solution. This technology enables customers to economically store vast amounts of data in DNA molecules, addressing the limitations of traditional digital storage methods.

Commonwealth Fusion is developing smaller, cost-effective tokamak fusion systems using high-temperature superconducting magnets to produce net energy from fusion. The company aims to deliver clean, abundant energy through its SPARC machine, paving the way for the first commercial fusion power plant, ARC, to combat climate change.

Electrified Thermal Solutions develops the Joule Hive™ Thermal Battery, which uses electrically conductive firebricks to convert and store electricity as high-temperature heat up to 1,800°C. This thermal battery technology enables zero-carbon industrial heating that is cost-competitive with natural gas. The system integrates easily with existing industrial processes to decarbonize hard-to-abate sectors like cement and steel.

Ephos designs and manufactures glass-based integrated photonic circuits using proprietary femtosecond laser writing techniques to minimize signal loss in computational devices. This technology enables the development of scalable classical and quantum infrastructures, addressing the need for efficient and high-performance computing solutions.

Finless Foods utilizes cellular agriculture to produce plant-based and cell-cultured seafood alternatives, starting with bluefin tuna, to address the overfishing and depletion of global fish stocks. Their technology enables the creation of sustainable seafood products that meet consumer demand while promoting ocean conservation.

Fork and Good develops cultivated meat production methods to improve sourcing practices and product quality. The company focuses on creating high-quality meat while minimizing the environmental impact associated with traditional livestock farming. Their goal is to achieve cost parity to make sustainable meat accessible for everyday consumption.

Gathered Foods produces plant-based seafood alternatives and proteins using sustainable farming practices to reduce reliance on animal agriculture. The company addresses food security challenges by offering nutritious, environmentally friendly options that cater to the growing demand for plant-based diets.

This biodesign company develops animal-free designer proteins that are sustainably cultivated and clinically validated for performance. Their products enable businesses to create environmentally friendly alternatives, supporting a transition to a plant-based future.

Holy Grail utilizes modular scrubbers to capture carbon dioxide from the atmosphere, which is then mineralized and formed into bricks for permanent above-ground storage. This technology addresses the urgent need for effective carbon removal solutions to combat climate change.

This company develops robotic systems for the selective collection of critical metals from the seabed. Their technology aims to provide a low-cost, high-performance source for essential minerals needed for the energy transition and technology sectors. The operation emphasizes preserving and protecting the ocean environment during the harvesting process.

Inner Cosmos offers a minimally invasive, sub‑dermal brain‑computer interface called the “Digital Pill” that continuously monitors neural activity and delivers closed‑loop electrical stimulation to rebalance mood‑related brain networks. The embedded device operates autonomously, enabling remote, cloud‑based personalization of therapy and eliminating the need for frequent clinic visits, with FDA‑cleared trial data showing sustained remission in depression patients.

Keel Labs develops Kelsun™ fiber, a sustainable material derived from seaweed biopolymers, aimed at reducing reliance on fossil fuel-based textiles. This innovation addresses the environmental impact of traditional materials by providing a renewable alternative that supports a circular economy.

Kula Bio develops a nitrogen biofertilizer using the naturally occurring microbe Xanthobacter, which is enhanced through proprietary technology to efficiently produce nitrogen at the root zone of crops. This approach reduces reliance on synthetic fertilizers, lowers environmental impact, and improves soil quality while ensuring consistent nutrient availability for optimal crop yield.

The startup develops bacteriophage-based therapies that utilize CRISPR-Cas3 technology to target and eliminate pathogenic bacteria in the human body. This approach enables rapid treatment initiation by physicians, leading to improved medical outcomes for patients with bacterial infections.

Max Space designs expandable inflatable habitats for space that provide significant cost savings and increased livable volume. These habitats address the challenge of limited and expensive space infrastructure by offering scalable solutions for both human habitation and storage in orbit.

Modern Hydrogen utilizes natural gas pyrolysis to convert methane into hydrogen gas and solid carbon, effectively reducing CO₂ emissions at the point of use. This technology addresses the challenge of high-grade heating applications that cannot be electrified, providing a low-cost, clean energy solution for commercial and industrial operations.

Modern Meadow produces BIO-VERA, a bio-fabricated material made from proteins and polymers, offering a sustainable alternative to traditional materials like leather and synthetics. BIO-VERA integrates into existing manufacturing processes for industries like automotive, footwear, and fashion, providing a more environmentally friendly option without sacrificing performance.

OpenZeppelin provides a suite of open-source tools and Defender Cloud Services for building, securing, and operating blockchain applications across multiple networks. Their smart contract audits and industry-standard contract libraries help developers minimize vulnerabilities and streamline the development lifecycle, ensuring the security of over $50 billion in total value locked.