64x Bio develops a high throughput genome engineering platform that accelerates the discovery of optimized mammalian cell lines for cell and gene therapies. This technology enables pharmaceutical and biotechnology companies to efficiently design and manufacture next-generation therapeutics, addressing the challenges of traditional cell line development.

Adventris is a biotechnology company that creates cancer immunotherapies by engineering high‑affinity, tumor‑specific antibodies, immune checkpoint modulators, and adoptive cell therapies. Its platform integrates protein engineering, biomarker discovery, and GMP‑compliant manufacturing to develop candidates for partnership with pharma and biotech firms, aiming to deliver durable anti‑tumor treatments.

Aether Bio develops machine learning algorithms and proprietary robotic hardware to engineer enzymes for the production of complex biochemical compounds. This technology enables manufacturers to create novel products at significantly reduced costs by efficiently indexing and searching trillions of enzyme sequences.

AKASA provides an AI-powered platform for revenue cycle management in healthcare, utilizing generative AI trained on clinical and financial data to enhance operational efficiency. The solution addresses high denial rates and lengthy accounts receivable cycles, resulting in improved margins and increased revenue for healthcare organizations.

Astranis designs and manufactures small, radiation-hardened telecommunications satellites for geostationary orbit, utilizing advanced digital processing technology to enhance internet access in remote regions. By reducing the number of satellites needed for constant service, Astranis lowers operational costs and simplifies user terminal requirements, making connectivity more affordable for underserved areas.

Bbb Tech provides an Algorithm Discovery Platform that uses cultured living neurons as a computational substrate to transform electrical representations of arbitrary data into richer, higher‑dimensional embeddings. By integrating biological neural tissue into AI pipelines, the platform enables continuous, low‑overhead inference with long‑term memory, real‑time adaptation, and pattern‑completion capabilities for research and development of post‑transformer models.

Bedrock Materials develops and manufactures engineered cathode materials for sodium-ion batteries, utilizing abundant metals like manganese and iron to provide a cost-effective alternative to lithium-ion technology. This approach addresses the critical mineral supply chain issues and supports the growing demand for affordable energy storage solutions in various mobility applications.

Berkeley Yeast bioengineers yeast strains that minimize diacetyl production and enhance flavor profiles for brewers, allowing for the creation of high-quality beers without undesirable off-flavors. Their custom yeast solutions improve fermentation efficiency and consistency, reducing reliance on expensive ingredients while delivering authentic taste in both alcoholic and non-alcoholic beverages.

BioRender offers a science visualization platform that enables life sciences professionals to create detailed scientific figures using a library of over 50,000 pre-made icons and customizable templates. This platform significantly reduces the time required to produce high-quality visuals, addressing the challenge of effectively communicating complex scientific concepts.

Brelle engineers intelligent electric powertrains and high-performance battery systems for electric and hybrid vehicles. Their modular architecture supports scalable voltage and capacity configurations with an AI-driven software platform for optimization and safety. The technology enables sub-10 minute charging times and high energy density for enhanced vehicle performance.

Causal Labs develops safe, steerable physics foundation models focused on atmospheric science. These models are designed to accurately understand and predict complex weather conditions. The resulting intelligence enables businesses and governments to make more informed decisions across sectors like aviation, energy, and emergency management.

Checkerspot utilizes a proprietary WING® Platform to optimize microbes for the biomanufacturing of structural oils, providing sustainable alternatives to petroleum-based materials. This technology enables industries to develop high-performance products while reducing reliance on fossil fuels and meeting environmental standards.

Contra is a platform that connects companies with over 800,000 independent professionals, enabling streamlined hiring, contract management, and payment processing for flexible workforce needs. It addresses the challenge of scaling teams efficiently by providing access to a diverse talent pool while ensuring compliance and reducing hiring costs by up to 50%.

Curative offers an employer-sponsored health insurance plan that eliminates copays and deductibles, providing members with $0 out-of-pocket costs for in-network doctor visits and preferred prescriptions. This model addresses the financial barriers to healthcare access, allowing employees to prioritize their health without the burden of unexpected medical expenses.

EOT provides the Twin Fusion platform, which integrates operational technology (OT) and information technology (IT) to enable real-time monitoring and optimization of industrial assets through machine learning and data analytics. This solution addresses the challenge of operational complexity by delivering actionable insights that enhance efficiency and reduce costs across enterprise-wide systems.

Epana Bio offers a high‑throughput single‑cell multi‑omics and AI platform that maps patient‑specific immune cell dysfunction in autoimmune diseases to identify druggable molecular targets. The system automates design of tailored biologics or small‑molecule candidates and integrates rapid preclinical validation, enabling pharma and biotech partners to develop mechanism‑based therapies with reduced side effects.

Floodbase provides an AI‑driven platform that generates a real‑time flood magnitude index from 17 satellite and sensor data streams. The index enables parametric flood insurance products that automatically trigger payouts within days, covering business interruption, crop loss, and infrastructure damage. The system integrates via API with insurance brokers and carriers, allowing them to design, price, and issue custom flood coverage at scale.

Foundation offers Passport Prime, an open‑source hardware device that consolidates Bitcoin private keys, 2FA codes, FIDO2 security keys, seed phrases, and up to 50 GB of encrypted file storage into a single, air‑gapped platform. Running the Rust‑based KeyOS microkernel and using QuantumLink for quantum‑resistant Bluetooth, it provides enterprise‑grade security features such as tamper protection, secure element storage, and Shamir‑based backup while supporting third‑party crypto apps.

Fyto develops automated cropping systems that utilize the aquatic plant lemna to enhance nutrient management on farms while producing high-value agricultural products. This technology addresses nutrient pollution and resource inefficiencies in farming by enabling sustainable crop production with reduced land, water, and labor inputs.

Provides an integrated platform for low-pass whole genome sequencing, combining assay development, scalable sequencing, and cloud-based data analytics to deliver cost-effective genomic insights. Enables applications in human, plant, and animal genomics, such as predicting disease risk, identifying genetic traits, and optimizing breeding strategies, while streamlining data processing and management for researchers and industry professionals.

General Galactic develops advanced spacecraft mobility solutions for sustained in-space operations. Their water-based propulsion system offers high thrust and specific impulse, enabling rapid maneuver and efficient orbital transfers. This technology allows customers to achieve greater delta-V and access unique orbits with lower operational costs.

Granza Bio develops a precision shell platform that utilizes autonomous "attack particles" from cytotoxic immune cells to deliver therapeutic cargo directly to cancer cells and hard-to-reach tissues. This technology minimizes toxicity and adverse side effects, enhancing the effectiveness of treatments for cancer and autoimmune diseases.

Headspace provides a cloud‑based mental‑health platform that combines guided meditations, mindfulness and sleep content with an AI‑driven companion, online therapy, and coaching in a single mobile app. The service offers personalized recommendations and enterprise tools—including usage analytics, HRIS integration, and EAP replacement—available via subscription for individuals and organizations.

The startup specializes in isotope enrichment technology to provide high-purity isotopes for the advanced energy and medical sectors. This technology addresses the need for sustainable, carbon-free solutions in energy production and medical applications, ensuring a reliable supply of essential isotopes.