Atom Computing develops gate-based quantum computers using arrays of optically-trapped neutral atoms, enabling the construction of scalable systems with over 1,000 error-corrected qubits. This technology addresses the need for high-performance quantum computing solutions that can support complex applications requiring long coherence times and optimized connectivity.

Axiom Space develops human-rated space infrastructure and operates end-to-end missions to the International Space Station (ISS), addressing the need for commercial access to low-Earth orbit. The company is also constructing Axiom Station, the first commercial space station, and creating next-generation spacesuits for future lunar and deep-space exploration.

Boom Supersonic manufactures the Overture, a commercial supersonic airliner designed to significantly reduce flight times while maintaining safety and sustainability through its Symphony turbofan engine. The company addresses the need for faster air travel by developing a supersonic travel solution that meets modern environmental standards and has garnered orders from major airlines.

CarbonCapture Inc. develops modular direct air capture (DAC) systems that utilize solid sorbents to extract over 500 tons of CO₂ from the atmosphere annually per unit. Their technology addresses climate change by enabling large-scale carbon removal and permanent geological storage of captured CO₂.

Commonwealth Fusion is developing smaller, cost-effective tokamak fusion systems using high-temperature superconducting magnets to produce net energy from fusion. The company aims to deliver clean, abundant energy through its SPARC machine, paving the way for the first commercial fusion power plant, ARC, to combat climate change.

This company develops and provides bioscience solutions focused on animal health and sustainable food production. They offer USDA-approved vaccines for honeybees to protect against major diseases and are developing vaccines for shrimp to combat White Spot Syndrome Virus. Their technology leverages natural immune defenses to deliver targeted disease protection across agricultural sectors.

Epirus develops solid-state, long-pulse high-power microwave systems integrated with AI for electronic warfare and air domain awareness. Their technology provides effective counter-drone and drone swarm protection, enhancing security for critical assets against evolving asymmetric threats.

E-Space provides a sustainable low Earth orbit (LEO) satellite communication platform that connects billions of IoT devices globally, enabling real-time data transmission without reliance on commercial traffic. This system addresses the need for affordable, resilient connectivity in high debris environments, significantly reducing costs by over 90% compared to traditional LEO networks.

Focused Energy is developing high repetition rate laser-driver systems and fast ignition targets to create a reliable fusion power plant that generates electricity, industrial heat, and hydrogen. This technology addresses the need for clean, alternative energy sources by harnessing fusion, which has the potential to significantly reduce carbon emissions.

Gilgamesh Pharmaceuticals develops new chemical entities targeting the root causes of depression, anxiety, and stress-related disorders through advanced medicinal chemistry and an AI-powered discovery platform. Their therapies include rapid-acting, non-hallucinogenic neuroplastogens and safer ibogaine analogs, offering improved efficacy and safety profiles for patients.

Gordian provides an in vivo drug discovery platform that uses aged animal “Patient Avatars”—models that naturally develop age‑related diseases—to screen pooled libraries of hundreds of therapeutic candidates in a process called Mosaic Screening. By integrating single‑cell sequencing, functional genomics, and AI‑driven analytics, the platform delivers quantitative efficacy data and prioritizes targets and candidates, helping pharma, biotech, and academic researchers improve the success rate of therapies for complex age‑related indications.

Halo Industries develops proprietary laser-based hardware for silicon carbide (SiC) wafering, achieving superior wafer-per-millimeter yield while minimizing material stress and kerf loss. The technology enhances manufacturing efficiency by reducing material, energy, and water consumption compared to traditional wafering methods.

Iridia utilizes Molecular Avatar Technology to embed unalterable molecular identities into products, ensuring authenticity and traceability without altering their appearance or functionality. This technology addresses counterfeiting and enhances supply chain visibility across various industries, including luxury retail and aerospace.

LyGenesis is a clinical-stage cell therapy company that utilizes a patient's lymph nodes as bioreactors to grow functioning ectopic organs, addressing the shortage of available organs for transplantation. Their technology allows one donated liver to potentially treat multiple patients with end-stage liver disease through a minimally invasive outpatient procedure.

Lyten develops and manufactures supermaterials based on its proprietary 3D Graphene™ platform, which captures carbon from methane and produces clean hydrogen. Its product line includes lithium‑sulfur batteries (LytCell™), graphene‑infused polyethylene composites (LytR™), and concrete additives that deliver higher energy density, reduced weight, and lower carbon footprints for EVs, aerospace, construction, and plastics manufacturers.

Morphoceuticals is a biotechnology platform utilizing multi-omics, bioelectric profiling, and AI to manipulate the bioelectrome, which governs tissue repair and organ regeneration. The company aims to enable regeneration and repair of damaged tissues in patients suffering from traumatic injuries, degenerative diseases, and organ failure.

MycoWorks develops Reishi™, a mycelium-based material that serves as a sustainable alternative to leather and plastics, addressing the environmental impact of traditional materials. By utilizing Fine Mycelium™ technology, the company produces high-quality, biodegradable materials suitable for various applications, including interior design and automotive interiors.

Overview Energy develops conversion technologies and management systems that optimize energy consumption in aerospace applications. The startup addresses inefficiencies in energy use, enabling operators to reduce operational costs and improve sustainability.

Paradromics is developing a high data-rate brain-computer interface (BCI) that directly accesses individual neural signals to enable communication for individuals with severe motor impairments. The Connexus Direct Data Interface translates neural activity into synthesized speech and cursor control, facilitating social connection and restoring independence for users.

ProRata AI develops AI-powered search, advertising, and attribution solutions designed to respect and compensate content creators. The platform provides transparent crediting and equitable value sharing models for publishers whose content is utilized by generative AI systems. This service ensures content partners receive fair revenue sharing and traffic referrals when their licensed work is accessed via AI search.

Pyka develops autonomous electric aircraft, including Pelican Spray for precision agricultural applications and Pelican Cargo for heavy-payload aerial logistics. These aircraft enhance crop protection and logistics efficiency by providing safe, cost-effective, and scalable solutions while minimizing chemical drift and enabling off-airport operations.

Quantum Space develops the Ranger spacecraft, a highly maneuverable platform engineered for persistent orbital presence and mission adaptability. This platform supports defense operations through surveillance, rapid response, and space domain dominance capabilities. Additionally, Ranger provides commercial satellite operators with life extension services through in-orbit refueling and servicing.

Robust.AI develops human-centered autonomous mobile robots (AMRs) that utilize AI-driven workflows to enhance warehouse and manufacturing operations. Their solutions increase throughput and employee retention by enabling rapid deployment without infrastructure changes, allowing businesses to scale flexibly as needs evolve.

Venus Aerospace is developing a reusable detonation ramjet engine that enables hypersonic flight, significantly reducing travel time across aviation and defense sectors. This technology addresses the limitations of current air travel speeds, paving the way for a new era of commercial hypersonic transportation with their Stargazer™ platform.