AAVantgarde Bio develops gene therapies utilizing proprietary Adeno-Associated Viral (AAV) vector technology to enable the delivery of large genes for the treatment of inherited retinal disorders. The company addresses the limitations of traditional AAV vectors, which restrict the payload size, thereby expanding the potential for genetic medicine in underserved patient populations.

BetaGlue Therapeutics develops YntraDose, a targeted nuclear radiotherapy platform that injects Yttrium‑90 microspheres embedded in a biocompatible glue directly into solid tumours. The system enables minimally invasive, imaging‑guided delivery of high‑dose beta radiation within the tumor, sparing surrounding tissue and offering a single‑session treatment option for hard‑to‑treat cancers such as pancreatic, liver and breast tumours.

Blubrake provides a modular anti‑lock braking system (ABS) for pedelecs and S‑pedelecs that can be integrated with any third‑party motor, battery, and brake setup. The kit installs in three steps and offers four selectable braking modes adjustable from the bike’s display, delivering automotive‑grade safety and a smooth, natural feel for riders, retailers, and manufacturers.

This startup specializes in additive manufacturing technology, providing customized design-to-production services that leverage generative design and large-format 3D printing. By integrating these methods, the company enables industries to produce complex parts with reduced lead times and material waste, overcoming the limitations of traditional manufacturing processes.

Casavo is a digital platform that provides instant home valuations using market data analysis, enabling homeowners to receive accurate estimates in just three minutes. By streamlining the sales process with dedicated consultants and fixed commission rates, Casavo addresses the complexities and inefficiencies of traditional real estate transactions in Europe.

Classiq Technologies provides a quantum computing software platform that enables the design, optimization, and execution of quantum algorithms by transforming high-level functional models into optimized quantum circuits. This technology allows users to quickly create complex circuits for various applications, significantly reducing development time from months to minutes while ensuring compatibility with any gate-based system and cloud provider.

Commonwealth Fusion is developing smaller, cost-effective tokamak fusion systems using high-temperature superconducting magnets to produce net energy from fusion. The company aims to deliver clean, abundant energy through its SPARC machine, paving the way for the first commercial fusion power plant, ARC, to combat climate change.

Cool Planet Technologies has developed a membrane-based carbon capture process that efficiently extracts carbon dioxide from industrial flue gas emissions at a lower cost than traditional methods. The company is constructing a plant capable of capturing 10,000 tonnes of CO2 per year, addressing the urgent need for effective carbon reduction in the cement industry.

CoreTigo provides IO-Link Wireless technology for industrial automation, enabling reliable, low-latency wireless communication for machine control and monitoring in manufacturing environments. This technology reduces the need for wired connections, enhancing flexibility and operational efficiency while minimizing changeover times and equipment footprint.

Coro provides a modular cybersecurity platform that integrates multiple security functions, including endpoint protection, email security, and data governance, into a single interface with one endpoint agent. This approach eliminates the complexity of managing disparate security tools, enabling organizations to effectively defend against malware, phishing, and insider threats while maintaining a streamlined security posture.

Deskbird offers an integrated workplace management platform that enables desk, room, and parking booking, visitor check‑in, and facility ticketing across multiple locations. The solution provides real‑time occupancy analytics and hybrid attendance tracking to help organizations optimize space utilization and reduce office costs. It integrates with common tools like Microsoft Teams, Outlook, Google Calendar, and Slack for seamless user adoption.

D-Orbit is the first in-space transportation company specializing in the precise deployment and removal of satellites using advanced orbital transfer vehicles. The company addresses the challenges of satellite maneuverability and end-of-life disposal, enhancing the sustainability of space operations.

Energy Dome develops a long-duration electricity storage system that utilizes a thermodynamic cycle to compress and store liquid CO2, enabling efficient energy retention and dispatch. This technology addresses the need for scalable, low-cost solutions to store renewable energy, facilitating grid decarbonization and enhancing energy reliability.

Hazy provides synthetic data solutions that generate realistic datasets while preserving the statistical properties of the original data, enabling organizations to utilize their data without compromising privacy. This technology addresses the challenge of inaccessible enterprise data due to privacy regulations, allowing businesses to enhance decision-making, accelerate AI development, and drive innovation.

iwoca provides unsecured, revenue‑based business loans to UK limited companies and partnerships, offering credit up to 20% of monthly turnover (up to £1 million) with fixed interest starting at 1.5% per 30 days and no early‑repayment fees. Loans are approved within hours through an online application that uses Open Banking or uploaded statements, and can be repaid over up to 24 months with optional top‑ups and invoice financing to bridge cash‑flow gaps.

Kamau Therapeutics is a clinical-stage company developing next-generation gene correction therapies using high-efficiency targeted gene integration. The company focuses on creating a new class of medicines designed to cure a range of serious and life-threatening diseases. Their work centers on delivering definitive, curative genetic treatments for patients with genetic disorders.

Leaf Space provides Ground Segment as a Service through its Leaf Line platform, offering on‑demand, global satellite connectivity via a proprietary network of 40+ owned ground stations in over 17 locations. Customers access the network with a unified RESTful API and web dashboard that automates pass scheduling, supports S‑, X‑, and Ka‑band waveforms, and delivers real‑time telemetry, command, and payload data with transparent per‑minute pricing and 24/7 support.

MatiPay provides a digital management solution that connects vending machines through telemetry and payment modules, enabling real-time monitoring, remote management, and secure transactions via an app. This technology addresses inefficiencies in the vending industry by enhancing user engagement, optimizing fleet operations, and improving payment experiences.

Mirta is a B2B platform that combines a wholesale marketplace with order management software, allowing retailers to access a diverse catalog of over 250 independent designers without minimum order requirements. The platform offers flexible 60-day payment terms and year-round stock availability, enabling businesses to test new products and adapt to seasonal trends efficiently.

MODIFI provides a digital platform that streamlines cross-border trade finance by offering instant payment solutions for exporters and flexible payment terms for buyers. The platform integrates trade management tools, including shipment tracking, into a single dashboard for enhanced operational control. This service enables businesses to manage global B2B payments securely while optimizing working capital and mitigating international transaction risk.

NeoPhore develops first‑in‑class small‑molecule inhibitors that transiently block DNA mismatch repair (MMR) in tumor cells, chemically mimicking the MMR‑deficient phenotype that responds to checkpoint inhibitor immunotherapy. By inducing a reversible MMR‑deficient state, their therapy reprograms otherwise resistant MMR‑proficient cancers to become immunogenic, enabling combination with existing chemotherapy, targeted therapy, or immunotherapy regimens and expanding the pool of patients who can benefit from durable immune responses.

Nuclidium provides a cyclotron‑produced copper‑61/‑67 radiopharmaceutical platform that combines PET imaging and targeted beta‑therapy within a single chelator‑ligand framework. The matched isotopic pair enables accurate dosimetry, streamlined manufacturing, and lower per‑dose costs, expanding access for nuclear medicine and oncology departments.

Phosphorus has developed a unified xIoT security management platform that automates the discovery, remediation, and monitoring of vulnerabilities across IoT, OT, and IoMT devices. This platform addresses the risks associated with inaccurate asset inventories, default credentials, and outdated firmware, enabling organizations to maintain secure and compliant cyber-physical systems at scale.

Pontoro is developing a digital asset platform that utilizes distributed ledger technology to enhance liquidity and transparency for private fund investments. The platform addresses the challenges of limited liquidity, complex structures, and inefficient price discovery in the private fund sector, enabling broader access for qualified investors.