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Main Sequence
Eveleigh, Australia
Main Sequence invests in deep‑tech founders tackling world‑scale challenges such as climate, health, space and industrial productivity. It deploys capital from seed through Series B, leveraging its partnership with CSIRO...
Portfolio
55+
Employees
30+
Founded
2016
AUM
≈ $1.0B
Investment focus
Stages
Seed → Series B
Industries
HardwareArtificial IntelligenceBiotechnologyClean Technology
Geographic scope
Global
Fund details
Funds
Fund II
Vintage 2021 • $250.0M
Fund I
Vintage 2017
Fund III
Vintage 2023
Sources
Main Sequence
Main Sequence invests in deep‑tech founders tackling world‑scale challenges such as climate, health, space and industrial productivity. It deploys capital from seed through Series B, leveraging its partnership with CSIRO and a global co‑investor network to accelerate scientific breakthroughs into commercial companies.
Portfolio
55+
Employees
30+
Founded
2016
AUM
≈ $1.0B
Funds
Fund II · Vintage 2021 • $250.0M
Fund I · Vintage 2017
Fund III · Vintage 2023
Showing 24 of 27 matched portfolio companies
Amber Electric provides a mobile app that enables users to monitor real-time wholesale energy prices and shift their electricity usage to periods when renewable energy is abundant and cheaper. By charging a monthly subscription fee, the company allows customers to save on energy costs while promoting the use of sustainable energy sources.
Funding: $51.6M
Rough estimate of the amount of funding raised
Australian Renewable Energy Agency
Australian Renewable Energy Agency
Funding: $51.6M
Rough estimate of the amount of funding raised
Arkus develops machine learning algorithms for genetic diagnostics that analyze genomic data to provide precise genetic insights. This technology enables early disease detection and the formulation of personalized treatment plans, improving healthcare outcomes.
Funding: $50.0K
Rough estimate of the amount of funding raised
Funding: $50.0K
Rough estimate of the amount of funding raised
Arlula provides a platform that automates the procurement and management of satellite imagery, reducing access time from days to minutes through powerful APIs and streamlined data processes. This enables businesses to quickly utilize critical Earth observation data, enhancing decision-making in a fast-paced environment.
Funding: $2.0M
Rough estimate of the amount of funding raised
Funding: $2.0M
Rough estimate of the amount of funding raised
An AI-powered dating app that acts as a virtual wingwoman, using natural language processing and machine learning to facilitate personalized matchmaking and conversation starters. It addresses the challenges of initiating and maintaining connections in online dating by providing users with tailored suggestions and support, improving engagement and compatibility.
Funding: $5.8M
Rough estimate of the amount of funding raised
Funding: $5.8M
Rough estimate of the amount of funding raised
Breaker is an audio application that enables users to discover and listen to over 20 million podcasts and videos, offering features like device synchronization and offline downloads. The platform addresses the challenge of podcast discovery and management, providing a streamlined experience for users to access their subscriptions and explore new content effortlessly.
10+
1K+Approximate amount of employees
Funding: $1.3M
Rough estimate of the amount of funding raised
Main Sequence Ventures
Main Sequence Ventures
Funding: $1.3M
Rough estimate of the amount of funding raised
Castlepoint Systems provides an all-in-one platform that utilizes Explainable AI for automated records classification, ensuring compliance and security across an organization’s data lifecycle. The solution addresses the risks associated with data management by offering visibility into sensitive records, enabling organizations to minimize data breaches and optimize data governance.
Cauldron offers a predictive analytics platform that uses NLP and ML to analyze geopolitical events and market-moving news. It quantifies the economic impact of political shifts, providing probabilistic forecasts and scenario analysis to help businesses manage risk and inform strategic planning.
ElectraLith develops a direct lithium extraction and refining technology that produces battery-grade lithium hydroxide in a single, modular process without the use of water or chemicals. This method addresses the environmental impact of traditional lithium production by utilizing renewable energy, enhancing sustainability in lithium supply chains.
Funding: $29.1M
Rough estimate of the amount of funding raised
Funding: $29.1M
Rough estimate of the amount of funding raised
JDoodle is an online coding platform offering a zero-setup, browser-based IDE for executing and debugging code across over 96 programming languages and frameworks. It provides APIs and embeddable IDEs for educational institutions and businesses, alongside AI-powered tools for code generation and debugging.
Funding: $2.2M
Rough estimate of the amount of funding raised
Main Sequence Ventures
Main Sequence Ventures
Funding: $2.2M
Rough estimate of the amount of funding raised
Lev is a commercial mortgage marketplace that utilizes real-time lender data and an AI-powered matching algorithm to streamline the financing process for capital market advisors. The platform enables sponsors and brokers to efficiently identify suitable lenders, manage deals, and automate follow-ups, significantly reducing the time and effort required to secure financing.
Funding: $100.0M
Rough estimate of the amount of funding raised
Cross River Bank
Cross River Bank
Funding: $100.0M
Rough estimate of the amount of funding raised
Loam provides an AI-enabled project developer assistant that creates and evaluates carbon reduction and environmental projects, helping organizations navigate the complexities of climate investments. By offering personalized decarbonization portfolios and automated access to funding opportunities, Loam enables businesses to effectively reduce their carbon footprint while capturing financial incentives.
Loam Bio utilizes patented microbial technology, specifically endophytic fungi, to enhance soil carbon stability and increase agricultural productivity. Their solutions, CarbonBuilder and SecondCrop, enable farmers to capture more carbon and unlock new revenue streams through carbon credits with minimal changes to existing practices.
Funding: $109.9M
Rough estimate of the amount of funding raised
Lowercarbon CapitalWollemi
Lowercarbon CapitalWollemi
Funding: $109.9M
Rough estimate of the amount of funding raised
Lumachain is a supply chain platform that utilizes AI and blockchain technology to provide real-time traceability of food products, monitoring their origin, condition, and location throughout the supply chain. The platform addresses inefficiencies and safety concerns in food production, ensuring ethical sourcing and improved quality control from farm to fork.
Funding: $22.1M
Rough estimate of the amount of funding raised
Chipotle Cultivate Foundation
Chipotle Cultivate Foundation
Funding: $22.1M
Rough estimate of the amount of funding raised
Number 8 bio develops feed additives under the BetterFeed brand designed to improve livestock feed efficiency and reduce enteric methane emissions. These solutions integrate easily into existing farm operations, enhancing nutrient absorption to boost animal growth and productivity. The company provides producers with a cost-effective path to improved performance while enabling food companies to achieve Scope 3 emissions reductions.
10+
1K+Approximate amount of employees
Funding: $8.2M
Rough estimate of the amount of funding raised
Main Sequence Ventures
Main Sequence Ventures
Funding: $8.2M
Rough estimate of the amount of funding raised
O is developing an IoT device that visualizes the human circadian clock to enhance individual and organizational performance through data-driven insights. The platform provides actionable recommendations based on sleep data, addressing productivity issues and mental health risks within teams.
Funding: $7.1M
Rough estimate of the amount of funding raised
Funding: $7.1M
Rough estimate of the amount of funding raised
Plotlogic provides real-time ore characterization through its Oresense® technology, enabling mine operators to accurately assess the location and material properties of rocks. This precision enhances ore recovery, reduces waste, and improves geological modeling, ultimately optimizing mining operations and environmental performance.
Funding: $63.2M
Rough estimate of the amount of funding raised
Galvanize Climate SolutionsSE Ventures
Galvanize Climate SolutionsSE Ventures
Funding: $63.2M
Rough estimate of the amount of funding raised
RA UNLIMITED harnesses solar photovoltaic technology to generate clean and affordable electricity for homes, businesses, and communities in the Philippines. The company addresses the reliance on fossil fuels by providing sustainable energy solutions that create jobs and enhance the quality of life for Filipinos.
Utilizes a recirculating shower system that captures, cleans, and reuses water in real time, reducing water and energy consumption by up to 80%. This technology provides a high-pressure, hygienic shower experience with a flow rate of 3 GPM while using only 0.5 GPM, making it suitable for residential, modular, and off-grid applications.
Funding: $5.6M
Rough estimate of the amount of funding raised
Raven Indigenous Capital Partners
Raven Indigenous Capital Partners
Funding: $5.6M
Rough estimate of the amount of funding raised
Regrow Ag provides an Agriculture Resilience Platform that enables companies to measure, manage, and reduce on-farm greenhouse gas emissions through scalable monitoring, reporting, and verification (MRV) of regenerative farming practices. This technology addresses the challenge of meeting net zero commitments by facilitating the adoption of sustainable agricultural methods across the supply chain.
Funding: $59.2M
Rough estimate of the amount of funding raised
Galvanize Climate Solutions
Galvanize Climate Solutions
Funding: $59.2M
Rough estimate of the amount of funding raised
RIOS is a Real Estate Industry Operating System that provides a platform for managing assignment listings, offers, and builder-consent processes through secure cloud-based solutions. The platform addresses inefficiencies and lack of coordination in the housing building and development market by streamlining workflows and enhancing data transparency.
Funding: $4.3M
Rough estimate of the amount of funding raised
Funding: $4.3M
Rough estimate of the amount of funding raised
Samsara Eco utilizes a proprietary recycling technology that transforms plastic waste into high-quality, 100% recycled plastics, enabling infinite reuse without the need for virgin materials. This approach addresses the critical issue of plastic pollution by significantly increasing recycling rates and reducing reliance on fossil fuels in plastic manufacturing.
Funding: $71.0M
Rough estimate of the amount of funding raised
Main Sequence VenturesTemasek Holdings
Main Sequence VenturesTemasek Holdings
Funding: $71.0M
Rough estimate of the amount of funding raised
Skykraft is developing a small satellite constellation for space-enabled air traffic management, enhancing global aviation safety through continuous communication and surveillance. Their technology optimizes airspace capacity and efficiency while reducing CO2 emissions via trajectory-based operations.
Funding: $79.2M
Rough estimate of the amount of funding raised
Australian Government
Australian Government
Funding: $79.2M
Rough estimate of the amount of funding raised
Terra provides a SaaS platform that lets creators design custom merchandise, order low‑cost samples, and launch a branded storefront that sells made‑to‑order products. The service handles manufacturing, fulfillment, and logistics, allowing creators to keep 100% of profits above production costs with no upfront inventory or minimum orders.
Funding: $500.0K
Rough estimate of the amount of funding raised
Funding: $500.0K
Rough estimate of the amount of funding raised
The startup offers an end-to-end machine learning platform that enables businesses to create multi-modal model ensembles, integrating explanations and continuous improvement frameworks. This technology allows organizations to focus on their specific business challenges rather than the complexities of machine learning model development.
Funding: $4.5M
Rough estimate of the amount of funding raised
Main Sequence Ventures
Main Sequence Ventures
Funding: $4.5M
Rough estimate of the amount of funding raised
Showing 12 of 28 unmatched portfolio companies
MGA Thermal
No website provided
We don't have a full profile for this company yet.
Quantum Brilliance
No website provided
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v2food
No website provided
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Eden Brew
No website provided
We don't have a full profile for this company yet.
Gilmour Space
No website provided
We don't have a full profile for this company yet.
Q-CTRL
No website provided
We don't have a full profile for this company yet.
Nourish Ingredients
No website provided
We don't have a full profile for this company yet.
SunDrive
No website provided
We don't have a full profile for this company yet.
Quasar Satellite Technologies
No website provided
We don't have a full profile for this company yet.
Advanced Navigation
No website provided
We don't have a full profile for this company yet.
Morse Micro
No website provided
We don't have a full profile for this company yet.
Kapiche
No website provided
We don't have a full profile for this company yet.