Main Sequence invests in deep‑tech founders tackling world‑scale challenges such as climate, health, space and industrial productivity. It deploys capital from seed through Series B, leveraging its partnership with CSIRO and a global co‑investor network to accelerate scientific breakthroughs into commercial companies.
Industries
Industry breakdown
Top industries in the portfolio
Geography
Geographic scope
Global
Geography breakdown
Darker regions = more portfolio companies
Top 5 countries
Australia
44.4%United States of America
22.2%Canada
7.4%France
3.7%Japan
3.7%Other
7.4%Countries with a higher share of the portfolio are shaded darker on the map.
Stages
Stage indicator
Seed → Series B
Stage breakdown
Portfolio by stage
Portfolio vintage
Companies by founded year
Fund details
Funds
Fund II
Vintage 2021 • $250.0M
Fund I
Vintage 2017
Fund III
Vintage 2023