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Madrona Venture Group
Seattle, United States
Madrona invests in early‑stage technology companies, from pre‑seed through acceleration, with a focus on AI, biotech, enterprise software, consumer marketplaces, and security. They back founders building transformative p...
Portfolio
58+
Employees
100+
Founded
1995
AUM
≈ $770.0M
Investment focus
Stages
Seed → Series C+
Industries
Artificial IntelligenceBiotechnologyConsumer GoodsCybersecurity
Geographic scope
United States
Fund details
Funds
Fund X
Vintage 2025 • $489.6M
Acceleration Fund IV
Vintage 2025 • $269.4M
Sources
Madrona Venture Group
Madrona invests in early‑stage technology companies, from pre‑seed through acceleration, with a focus on AI, biotech, enterprise software, consumer marketplaces, and security. They back founders building transformative products, leveraging deep roots in the Pacific Northwest and a growing presence on the West Coast, providing capital, operational support, and strategic expertise for the long run.
Portfolio
58+
Employees
100+
Founded
1995
AUM
≈ $770.0M
Funds
Fund X · Vintage 2025 • $489.6M
Acceleration Fund IV · Vintage 2025 • $269.4M
Stages
Seed → Series C+
Industries
Artificial IntelligenceBiotechnologyConsumer GoodsCybersecurityEnterprise Software
Geographic scope
United States
Sources
Showing 24 of 55 matched portfolio companies
A-Alpha Bio utilizes its AlphaSeq and AlphaBind platforms to generate high-resolution protein-protein interaction data at scale, enabling the discovery and engineering of effective protein therapeutics. The company addresses the challenge of limited high-quality interaction data, which hampers the understanding and treatment of diseases such as cancer and neurological disorders.
Funding: $45.6M
Rough estimate of the amount of funding raised
U.S. Department of Defense
U.S. Department of Defense
Funding: $45.6M
Rough estimate of the amount of funding raised
adyn offers The Birth Control Test, a personalized assessment that analyzes an individual's hormone levels and genetic risk to identify the most suitable birth control options with minimal side effects. This approach addresses the high rate of discontinuation among birth control users due to adverse reactions, providing a scientifically informed pathway to effective contraceptive choices.
Funding: $2.6M
Rough estimate of the amount of funding raised
Funding: $2.6M
Rough estimate of the amount of funding raised
Aizen Therapeutics utilizes a novel AI model, DaX™, trained on receptor-ligand physics, to design modern peptide drugs incorporating non-canonical amino acids. This platform expands the accessible design space for peptide therapeutics beyond naturally occurring building blocks. The company focuses on guided diffusion to engineer oral biologics capable of targeting complex indications like cytokine inhibition.
Funding: $13.0M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $13.0M
Rough estimate of the amount of funding raised
AnsweriQ provides AI-driven automation for customer service through self-service and agent assistance technologies, enabling real-time responses and process automation. This solution significantly reduces average handle times and case volumes, enhancing customer satisfaction while lowering operational costs.
Funding: $5.0M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $5.0M
Rough estimate of the amount of funding raised
Archon Bio develops geometrically tunable protein therapeutics called Antibody Cages (AbCs) by integrating generative AI design with structural control. This platform enables precise engineering of biodistribution, engagement, and function to target previously intractable therapeutic pathways. The company transforms biologics into differentiated drugs by leveraging structural innovation to improve therapeutic effect.
Funding: $20.0M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $20.0M
Rough estimate of the amount of funding raised
Axiom develops an AI mathematician as the initial component of a larger self-improving superintelligent reasoner. This system focuses on advancing automated reasoning capabilities through iterative learning. The core offering is foundational AI designed for complex problem-solving and mathematical inference.
20+
3K+Approximate amount of employees
Funding: $64.0M
Rough estimate of the amount of funding raised
B Capital
B Capital
Funding: $64.0M
Rough estimate of the amount of funding raised
Bobsled provides a data product platform designed to transform data into AI-ready assets and conversational experiences. The platform enables secure data sharing across various environments via a data access network with zero-copy capabilities. It supports agentic analytics and workflows by integrating context and semantic models for accurate, automated data reasoning.
Funding: $17.0M
Rough estimate of the amount of funding raised
GreycroftMadrona
GreycroftMadrona
Funding: $17.0M
Rough estimate of the amount of funding raised
Bolt.new is an AI-powered platform that generates functional code for web applications and websites from natural language descriptions. It streamlines development by translating user prompts into code, integrating with Figma designs and GitHub repositories to accelerate prototyping and deployment.
Funding: $105.5M
Rough estimate of the amount of funding raised
Funding: $105.5M
Rough estimate of the amount of funding raised
ClawdTalk provides a voice interface layer that connects existing text-based bots to the public telephone network. It handles the entire voice pipeline, including speech-to-text, text-to-speech, and call management, allowing users to interact with their bots via natural voice commands. This service eliminates the need for developers to manage complex telephony infrastructure or expose their bots publicly via gateways.
Funding: $47.0M
Rough estimate of the amount of funding raised
Alkeon CapitalMadrona
Alkeon CapitalMadrona
Funding: $47.0M
Rough estimate of the amount of funding raised
Codified provides AI governance solutions to prevent sensitive data leakage from generative AI and RAG applications. The platform classifies and codifies data access policies across sources to ensure secure and scalable information retrieval. This allows teams to leverage AI insights safely without exposing PII, trade secrets, or confidential information.
Funding: $4.3M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $4.3M
Rough estimate of the amount of funding raised
Deepgram provides a voice AI platform that offers APIs for speech-to-text, text-to-speech, and natural language understanding, enabling developers to integrate advanced voice capabilities into their applications. The technology addresses the need for accurate and efficient transcription and voice interaction, delivering real-time processing and support for over 30 languages at a significantly lower cost and faster speed than traditional solutions.
Funding: $103.2M
Rough estimate of the amount of funding raised
Alkeon CapitalMadrona
Alkeon CapitalMadrona
Funding: $103.2M
Rough estimate of the amount of funding raised
Echodyne develops metamaterials-based electronically scanned array (MESA) radar technology that provides low size, weight, power, and cost (SWaP-C) solutions for enhanced situational awareness. Their radars deliver precise real-time tracking data, enabling defense, government, and commercial sectors to make informed decisions in complex environments.
Funding: $135.0M
Rough estimate of the amount of funding raised
Baillie GiffordBill Gates
Baillie GiffordBill Gates
Funding: $135.0M
Rough estimate of the amount of funding raised
Finpilot utilizes artificial intelligence to analyze corporate documents and generate structured data, enabling rapid and accurate decision-making in finance. The platform addresses the inefficiencies of manual document processing by automating knowledge extraction and report generation, significantly enhancing workflow speed and reliability.
Funding: $4.5M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $4.5M
Rough estimate of the amount of funding raised
Gradial provides an agentic platform to automate enterprise content operations, including authoring, production, QA, and page creation. The system integrates with existing tools like CMS and Figma to streamline workflows and ensure brand adherence. This automation accelerates content delivery, reduces service level agreements, and maintains compliance across omni-channel experiences.
Funding: $13.0M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $13.0M
Rough estimate of the amount of funding raised
Groundlight provides a computer vision platform that allows users to query real-time visual data using natural language, eliminating the need for complex coding or extensive data preparation. The technology enables immediate deployment of customized AI models for tasks such as quality control and process monitoring, ensuring accurate results from day one without requiring pre-existing datasets.
Funding: $10.0M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $10.0M
Rough estimate of the amount of funding raised
Juno provides an integrated travel and expense management platform for complex itineraries, including guest and contractor travel. It streamlines booking with in-policy compliance and automates expense reimbursement with AI-powered receipt verification, aiming for rapid traveler payouts. The platform consolidates payments and offers proactive disruption management for a seamless experience.
Funding: $2.0M
Rough estimate of the amount of funding raised
Bungalow Capital ManagementMadrona
Bungalow Capital ManagementMadrona
Funding: $2.0M
Rough estimate of the amount of funding raised
Lassen Peak develops a technology that transforms weapon detection procedures into safe and efficient experiences by utilizing advanced scanning and analysis methods. This approach mitigates the risks associated with traditional detection processes while ensuring a dignified experience for individuals undergoing security checks.
Funding: $36.5M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $36.5M
Rough estimate of the amount of funding raised
Nosis Biosciences operates an AI‑driven platform called Connexa that designs receptor‑targeted RNA therapeutics and their delivery vehicles for a broad range of cell types, including heart, lung, kidney, muscle, intestinal, blood, and brain cells. By integrating physics‑aware deep learning, single‑cell biology, and high‑throughput chemistry, the company creates gene‑silencing medicines that can be administered subcutaneously with long dosing intervals, aiming to treat chronic diseases. Revenue is generated through partnerships and licensing agreements with pharmaceutical developers seeking RNA‑based drug candidates.
Alation provides an Agentic Data Intelligence Platform that unifies data cataloging, governance, lineage, and quality management into a single hub. The platform utilizes agentic workflows to automate documentation, enforce policies, and accelerate the delivery of trusted data products for AI and analytics initiatives. This centralized approach enables self-service data discovery while ensuring compliance and providing explainable insights from enterprise data assets.
Funding: $17.5M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $17.5M
Rough estimate of the amount of funding raised
Outbound AI provides a Conversation AI Cloud specifically engineered for healthcare revenue cycle operations. Their AI agents automate and streamline burdensome, phone-based administrative tasks like billing and claims processing. This technology augments existing staff productivity while accelerating time to payment for healthcare organizations.
Funding: $16.0M
Rough estimate of the amount of funding raised
MadronaSpringRock Ventures
MadronaSpringRock Ventures
Funding: $16.0M
Rough estimate of the amount of funding raised
Ovation provides a cloud-based laboratory information management system (LIMS) tailored for molecular diagnostic labs, facilitating lab workflows, sample tracking, and document management. The platform enhances clinical diagnostics by enabling efficient data collection and organization, which supports informed decision-making in drug discovery and patient stratification.
Funding: $21.5M
Rough estimate of the amount of funding raised
SignalFire
SignalFire
Funding: $21.5M
Rough estimate of the amount of funding raised
Ozette has developed a cloud-native, AI-driven platform for single-cell immune monitoring that enhances the analysis of cytometry data, enabling rapid extraction of biological insights. This technology addresses the limitations of traditional manual workflows, allowing researchers to uncover critical immune system complexities that inform targeted therapies and improve patient outcomes.
Funding: $32.0M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $32.0M
Rough estimate of the amount of funding raised
Pendulum provides an advanced social intelligence platform that moves beyond traditional social listening capabilities. The system automatically transcribes audio and video content while detecting logos and influencers within visual media across numerous channels. This data enrichment delivers actionable, executive-level insights for brand management, crisis response, and competitive benchmarking.
Funding: $19.9M
Rough estimate of the amount of funding raised
Madrona
Madrona
Funding: $19.9M
Rough estimate of the amount of funding raised
Pin is a recruitment platform that employs AI-driven sourcing algorithms and ATS integration to efficiently identify and connect with hard-to-find candidates. By automating key hiring processes, Pin reduces the recruitment timeline from several weeks to under two weeks, enabling businesses to focus on team building and growth.
Funding: $3.0M
Rough estimate of the amount of funding raised
Expa
Expa
Funding: $3.0M
Rough estimate of the amount of funding raised
Showing 3 of 3 unmatched portfolio companies