2NDNATURE provides a cloud-based software solution that streamlines compliance with MS4 permit regulations and enhances stormwater management through data-driven prioritization and green infrastructure support. The platform helps organizations convert stormwater runoff into a resource, reducing flooding and pollution while maximizing environmental benefits and financial incentives.

This company offers automatic tire inflation systems for commercial vehicles that maintain optimal tire pressure using the wheel's rotation. By ensuring consistent tire pressure, the system improves fuel efficiency, reduces emissions, and enhances safety for fleet operators.

Ateios provides the RaiCure™ platform, a radiation‑curable polymer coating that replaces thermal curing and toxic solvents in battery electrode manufacturing. The drop‑in solution enables thicker, higher‑density electrodes, cuts energy use by up to 82%, and speeds production up to five times while reducing capital and operating costs and eliminating PFAs.

Boom Supersonic manufactures the Overture, a commercial supersonic airliner designed to significantly reduce flight times while maintaining safety and sustainability through its Symphony turbofan engine. The company addresses the need for faster air travel by developing a supersonic travel solution that meets modern environmental standards and has garnered orders from major airlines.

Cadenza Innovation develops a modular lithium-ion battery energy storage system featuring non-propagating thermal runaway protected cells, designed for high energy density and low cost. The technology addresses the need for safe, efficient energy storage solutions in electric vehicles, grid applications, and backup power systems, significantly reducing total cost of ownership compared to traditional lead-acid batteries.

Chromatic develops the RX-AM™ platform, which utilizes chemical reactions to 3D print industrial-strength elastomeric parts without the need for melting or post-processing. This technology enables manufacturers to produce durable, customizable components on various substrates, reducing costs and waste associated with traditional injection molding methods.

CNote provides a secure platform for FDIC-insured deposits and fixed income solutions, connecting investors with a vetted network of Minority Depository Institutions and Community Development Financial Institutions (CDFIs). This approach directly channels capital into underserved communities, creating jobs and supporting BIPOC-owned small businesses while promoting economic and racial justice.

DermaSensor provides an FDA Cleared, handheld device that uses optical spectroscopy and proprietary AI algorithms to non-invasively assess suspicious skin lesions. This technology delivers instant risk assessment outputs to aid healthcare providers in making objective referral decisions for melanoma, basal cell carcinoma, and squamous cell carcinoma. The system enhances clinical confidence by offering rapid, objective data to supplement traditional visual assessment at the point of care.

Everykey provides a universal smart key that uses proximity technology to wirelessly unlock devices and manage passwords, enhancing security through physical presence authentication. This solution mitigates the risks of phishing and unauthorized access while simplifying identity management for users and organizations.

ExpressCells specializes in the development of custom cell lines using advanced genetic engineering techniques for biological research and drug discovery. This service addresses the need for tailored cellular models that enhance experimental accuracy and accelerate the drug development process.

Gila Therapeutics is developing a topical lingual signaling platform that utilizes micro-dose PYY to activate the Nucleus Tractus Solitarius, targeting brain areas that regulate food intake and metabolism without entering the bloodstream. This approach aims to provide a safer and more effective treatment for obesity and cardiometabolic disorders, minimizing side effects commonly associated with traditional therapies.

Guardian Medical develops CapSure™, a pre-validated sterile packaging system for medical implants that combines an integrated seal with a rigid design to enhance protection and reduce the need for complex sealing equipment. This solution minimizes sterilization, shipping, and storage costs while supporting sustainability goals through its recyclable materials and smaller footprint.

Healionics develops the _STARgraft_ synthetic vascular graft, which utilizes a Sphere Templated Angiogenic Regeneration biomaterial to enhance blood access for dialysis patients. This technology significantly reduces the risks of occlusion and infection associated with traditional grafts, improving patient outcomes and lowering treatment costs.

Honeycomb Credit operates a peer-to-peer lending platform that connects individual investors with small businesses seeking funding, allowing investments starting at $100. This platform addresses the challenge of limited access to capital for local businesses by facilitating community-driven financial support, resulting in over $30 million invested and 1,142 jobs supported.

INOVUES provides non-invasive window retrofit technology that enhances existing glazing systems by transforming single- and double-pane windows into high-performing multi-pane systems, improving insulation by up to ten times. This solution reduces energy consumption and carbon emissions by up to 40% without the need for replacement or disruption to building operations.

INVERSA produces ethical exotic leathers from invasive species through sustainable sourcing and processing methods, effectively reducing the ecological impact of these species. This approach provides a high-quality leather alternative that meets both environmental standards and market demand.

Iris Automation develops advanced collision avoidance systems using computer vision technology for both crewed and uncrewed aircraft. Their solutions enhance airspace safety by providing real-time detection of nearby aircraft, enabling operations beyond visual line of sight (BVLOS) while meeting regulatory standards.

Irrigreen offers a cloud‑connected sprinkler system that replaces traditional mechanical zones with digital heads capable of delivering 16 ultra‑precise streams per head. The platform lets users map custom irrigation zones in a mobile app, automatically adjusts watering based on real‑time weather and soil data, and supports smart‑home integration, reducing water consumption by up to 50 % and simplifying installation.

Kidizen runs a peer‑to‑peer marketplace where parents buy and sell vetted secondhand children’s clothing and gear. The platform includes AI‑driven size matching, built‑in escrow payments, automated shipping label generation, and a sustainability dashboard that quantifies saved resources. It is available via web and native mobile apps, offering advanced filters and a reputation system for trusted transactions.

Lark offers a digital Diabetes Prevention Program that utilizes AI coaching, smart devices, and tele-monitoring to help users achieve weight loss and manage their health remotely. The program provides 24/7 access to personalized coaching and resources, aiming to reduce the risk of diabetes for participants, often at no cost with eligible insurance.

The company provides a semiconductor platform for wearable devices that captures vital signs and wirelessly transmits them to the cloud. Their platform offers multiple sensor interfaces and radio technologies, enabling the development of clinical-grade remote monitoring wearables. This allows clients to efficiently create and commercialize cost-effective health monitoring solutions.

Lingrove manufactures ekoa®, a low-carbon natural fiber composite made from renewable plant-based fibers and resins, utilizing a proprietary process that ensures high durability and a superior strength-to-weight ratio. This material effectively replaces traditional wood, plastics, and metals in various applications, providing a sustainable solution for interior design and automotive finishes.

Luminary Therapeutics develops allogeneic cell therapies using its Gamma 2.0+ platform to target solid tumors and B cell malignancies, addressing challenges such as antigen escape and limited tumor infiltration. The company aims to reduce relapse rates and manufacturing costs, providing more effective treatment options for underserved patient populations.

Natilus designs and manufactures blended‑wing‑body (BWB) aircraft that combine the fuselage and wing into a single lift‑generating structure, delivering up to 30% fuel savings, higher payload capacity, and reduced emissions. Its product lines include KONA, an autonomous‑capable regional cargo aircraft, and Horizon EVO, a passenger jet that can carry over 200 passengers on long‑haul routes, both compatible with existing airport infrastructure and dual‑fuel (Jet A and SAF) operations.