3Laws Robotics provides a software‑only safety layer called Supervisor that can be inserted into existing autonomy stacks to monitor sensor data and filter control commands for real‑time collision avoidance, geofencing, stabilization, and fault management. The plug‑and‑play module integrates with ROS 2 Nav2 and other middleware, eliminating the need for hardware e‑stop mechanisms while delivering health diagnostics and configurable safety thresholds for robots, drones, and autonomous vehicles.

Aralez Bio utilizes engineered enzymes to produce noncanonical amino acids, which are essential building blocks for peptide drugs, in a sustainable and cost-effective manner. This approach significantly reduces manufacturing time and costs, addressing the challenges of traditional amino acid production that often leads to long lead times and supply chain uncertainties.

Calicat develops non-Iridium electrocatalysts and advanced stack components for electrolyzers, utilizing a proprietary AI-driven catalyst discovery process to enhance material performance. This technology addresses the high levelized cost of hydrogen by improving electrolyzer efficiency and reducing reliance on scarce precious metals.

Captura utilizes renewable energy to perform Direct Ocean Capture, extracting CO2 from seawater to enhance the ocean's natural carbon removal processes without additives or by-products. This technology addresses the urgent need for scalable carbon removal solutions to mitigate climate change impacts.

CatenaBio has developed the CysTyr™ platform, which utilizes the Catenase™ enzyme to form proprietary C-Y Bonds™ between proteins using native amino acids, enabling the rapid and selective attachment of multiple therapeutic modalities. This technology addresses the limitations of current protein conjugation methods, facilitating the creation of novel therapeutics for autoimmune disorders, oncology, and vaccine development.

Opeator is a fermentation technology company that utilizes an anaerobic process to enhance the efficiency and scalability of industrial fermentation. By enabling extended fermentation runs and employing low-cost bioreactors, the company improves process robustness and reduces operational costs for various industries.

The startup develops a real-time health monitoring platform that integrates a multi-analyte biosensor with scalable AI to detect and analyze biomarkers with high precision. This technology enables early disease diagnosis and management by automating health data processing and providing actionable insights to improve patient care and outcomes.

This company converts diverse waste biomass feedstocks into fermentable sugars and chemical intermediates using a proprietary, feedstock-agnostic process. Their technology achieves high sugar recovery rates while utilizing commercially available equipment, reducing capital expenditure for biomanufacturing. The resulting products support the production of synthetic aviation fuels and cost-competitive chemicals, enhancing supply chain resilience.

This company develops a non-invasive blood pressure monitoring device using sound waves for continuous, 24/7 measurements. Their technology enables remote patient monitoring and at-home use, improving accessibility to vital sign tracking.

Holoclara develops immunotherapy treatments for autoimmune disorders using nematode-derived molecules. The company aims to provide relief for millions suffering from debilitating diseases by targeting the underlying immune responses associated with these conditions.

The startup provides technology solutions for the healthcare and agriculture sectors, focusing on precision farming and data analytics to enhance crop yield and resource management. By utilizing IoT sensors and machine learning algorithms, the company addresses inefficiencies in farming practices and healthcare delivery, leading to improved productivity and reduced operational costs.

Hydrosat utilizes thermal infrared satellite technology and proprietary algorithms to provide field-level and regional analytics for irrigation and crop management. The company helps governments and farmers optimize water usage while increasing crop yields across millions of hectares globally.

Iambic Therapeutics utilizes a physics-based AI-driven drug discovery platform to explore chemical space and identify novel mechanisms of action for drug candidates. The platform accelerates the development of first-in-class therapeutics by optimizing target product profiles and delivering high-quality leads at a pace significantly faster than traditional methods.

ImYoo operates a patient-enabled biodiscovery platform focused on immune dynamics. The company facilitates patient-centric studies by enabling at-home self-collection of small blood volumes for high-resolution single-cell genomics assays. This approach aims to uncover molecular signals to guide precision diagnosis and therapeutic strategies for complex diseases like Lupus.

Mango provides the M6, a fully automated microbial detection system for quality control laboratories. This platform uses advanced imaging and machine learning to deliver sterility and bioburden results in hours, significantly faster than traditional methods. The system integrates seamlessly into regulated workflows, offering accurate colony quantification and 21 CFR Part 11 compliant reporting.

Membrion develops electro-ceramic desalination technology that efficiently removes problematic ions from industrial wastewater, enabling compliance with regulatory standards while minimizing operational costs. Their membranes are designed to withstand extreme conditions, reducing the need for pre-treatment and enhancing water circularity in wastewater management systems.

Miist Therapeutics provides a vibration‑driven, breath‑actuated inhaler that generates sterile aqueous particles half the size of conventional aerosols, enabling peripheral lung deposition and systemic drug delivery within seconds. The platform delivers rapid‑onset therapies for acute conditions such as nicotine cravings and migraine, and includes programmable dose tapering for sustained treatment.

Mitico provides an accessible solution for the mass mitigation of industrial carbon emissions post-combustion. The technology captures and purifies carbon dioxide from flue gases with low CO2 concentrations using a simple chemical sorbent in conventional packed bed reactors. This system offers competitive CAPEX and OPEX while utilizing low-impact, earth-abundant materials for effortless integration.

Molecular Instruments provides an enzyme‑free, HCR™‑based platform that merges in situ hybridization and immunofluorescence in a single incubation, allowing simultaneous detection of up to ten RNA targets and unlimited protein markers in tissue sections. The HiFi Encoder amplifies primary‑antibody signals without secondary reagents or stripping steps, preserving tissue integrity and delivering quantitative fluorescence compatible with standard microscopes.

Nuanced Health develops a drug discovery and development platform by systematically humanizing mouse microbiomes to account for environmental drivers of disease. This approach utilizes next-generation preclinical models that recreate the heterogeneity of human populations, addressing the limitations of traditional singular animal models. The platform generates high-resolution multi-omic datasets and actionable insights to enhance the translatability and efficacy prediction of novel therapeutics.

Persperity Health develops digital physiology solutions using noninvasive, sweat-based biosensors for continuous hormone monitoring. The platform delivers real-time, personalized data to support women through ovulation tracking, fertility treatments, and menopause management. This technology provides clinical-grade estradiol insights, enabling proactive health decisions without traditional blood testing.

Pie offers a tax management app that provides real-time tax calculations, automated bookkeeping, and direct submission to HMRC, specifically designed for high earners and self-employed individuals. The app simplifies the tax filing process by consolidating multiple income streams and providing sector-specific tax assistance, reducing the complexity and time associated with tax returns.

PINC’s NanoPPLN platform integrates periodically poled lithium niobate waveguides into silicon‑compatible photonic chips, providing a compact, scalable source of strong second‑order optical nonlinearity. This enables on‑chip frequency conversion, parametric amplification, mode‑locked lasers, and quantum light generation, allowing photonic integrated circuits to deliver high‑performance sensing, data‑center communications, and AI‑accelerated computing without bulky external crystals.

PolySpectra develops Cyclic Olefin Resins (COR) for industrial additive manufacturing, enabling engineers to 3D print durable, impact-resistant components that withstand extreme conditions. Their technology addresses the limitations of traditional photopolymers by providing a robust solution for producing end-use parts with high thermal and chemical resistance.