Aalo manufactures compact nuclear reactors that utilize liquid metal coolant and UZrH fuel to achieve high energy density and simplified safety systems. These reactors can generate electricity at a target cost of 3¢ per kWh, providing a scalable solution for energy needs ranging from small data centers to large cities.

Ambient Photonics develops low light energy harvesting photovoltaic cells that convert ambient light into usable power for smart home and IoT devices. This technology eliminates the need for batteries, addressing the environmental impact of battery waste while providing a sustainable energy source with up to three times the power density of traditional indoor solar cells.

Conventional primary metal production relies on pyrometallurgical smelting, which consumes large amounts of fossil fuel, generates high CO₂ emissions, and cannot efficiently process heterogeneous feedstocks such as end‑of‑life batteries or mixed industrial scrap. The inability to recycle these complex streams limits resource recovery and increases waste disposal costs. Boston Metal offers a high‑temperature electrochemical processing platform that replaces carbon‑intensive smelting with electrically driven reduction reactions.

This company develops perovskite-based solar power products that seamlessly integrate into existing PV module manufacturing. Their technology improves power production, enabling users to lower costs and boost performance in terrestrial solar applications.

Commonwealth Fusion is developing smaller, cost-effective tokamak fusion systems using high-temperature superconducting magnets to produce net energy from fusion. The company aims to deliver clean, abundant energy through its SPARC machine, paving the way for the first commercial fusion power plant, ARC, to combat climate change.

Constructive.Bio utilizes a dual-technology platform that combines de novo genome synthesis and engineered translation to create programmable biomolecules with high fidelity. This approach addresses the limitations of traditional biomanufacturing by enabling the production of customized bioproducts, including phage-resistant strains and next-generation therapeutics.

Debut combines biotechnology with brand development to create sustainable beauty products using eco-friendly active ingredients. The company addresses the environmental impact of traditional cosmetics by offering climate-positive solutions that enhance consumer well-being.

The startup develops ultra-energy-efficient neural network models that utilize nonlinear dynamics and space-time sparsity, inspired by biological neural networks, to enable large-scale processing at the edge. These models provide ultra-low latency, low power consumption, and enhanced user privacy for businesses requiring efficient user interfaces in complex processing tasks.

Feon Energy develops high-performance, breakthrough electrolytes using a pharmaceutical-inspired discovery platform to overcome limitations in next-generation battery chemistries. Their EDGE platform technology enables electrolytes that deliver significant improvements in energy density, safety, and cost for various battery applications. These tailored molecules are fully compatible with existing manufacturing processes, supporting advancements in mobility and clean energy storage.

This company manufactures gallium nitride (GaN) transistors and integrated circuits (ICs) for 5G communications and power conversion applications. Their GaN FinFET technology enables the creation of semiconductor materials with enhanced properties for use in electronics and energy management.

Hedron operates a network of data satellites that facilitate real-time data transmission between space and Earth. This technology addresses the challenge of limited connectivity for remote and underserved areas, enabling enhanced communication and data access globally.

Hoxton Farms develops and releases open-source artificial intelligence models specifically for the biomanufacturing sector. These tools, such as BrightQuant and LipiQuant, aim to enhance efficiency and predictability in biological production processes. The company provides foundational AI assets to advance the capabilities of industrial biotechnology operations.

iPronics develops integrated programmable photonic systems that utilize photonic circuits for high-speed data processing. This technology provides efficient and scalable solutions for telecommunications and data centers, meeting the demand for faster and more energy-efficient information transfer.

Mainspring has developed a linear generator that provides onsite, fuel-flexible power generation, enabling users to transition to cleaner energy sources while maintaining reliability and cost-effectiveness. This technology addresses the need for local power solutions that can adapt to varying fuel types and support the integration of renewable energy into the grid.

Mantle specializes in metal 3D printing technology that produces precision tooling components, significantly reducing lead times and costs for manufacturers. By automating toolmaking processes, Mantle addresses labor shortages and enhances production efficiency with high-quality mold and die inserts.

Nitricity produces plant-based, climate-smart nitrogen fertilizer using air, water, clean energy, and almond shells, achieving zero carbon emissions during production. This addresses the high greenhouse gas emissions associated with conventional fertilizer manufacturing while providing a reliable, efficient nutrient source for sustainable agriculture.

The startup develops food-grade nanovesicles that mask the flavors of functional ingredients and enhance their bioavailability in food and beverage products. By optimizing ingredient performance, the company enables food manufacturers to improve taste and introduce new functionalities, ultimately enhancing product appeal and consumer benefits.

Osmoses focuses on addressing major planetary challenges by working with the smallest molecules. The company develops technology centered around molecular interactions to solve significant environmental problems. They invite partners to pilot and implement their solutions.

Pallidus develops proprietary silicon carbide (SiC) wafer technology that enhances the performance and efficiency of power electronics in applications such as transportation, telecom, and green energy. By improving the cost-quality ratio of SiC wafers, Pallidus addresses the high manufacturing costs and quality limitations currently faced in the power electronics industry.

Phytoform Labs utilizes artificial intelligence and genome editing to enhance plant DNA diversity, creating resilient and sustainable crops that can withstand climate change. Their technology accelerates the development of diverse crop traits, addressing the urgent need for future-proof agricultural solutions.

Quaise is developing a gyrotron-powered drilling platform that utilizes millimeter-wave technology to vaporize boreholes and access deep geothermal energy at depths of up to 20 kilometers and temperatures of 500°C. This approach enables the rapid deployment of clean, renewable energy by repurposing existing fossil fuel infrastructure, addressing the urgent need for scalable and sustainable energy solutions.

Radian Aerospace is developing Radian One, a single-stage-to-orbit spaceplane that utilizes horizontal takeoff and landing capabilities to achieve full reusability. This technology addresses the high costs and logistical challenges of traditional vertical launch systems, enabling more frequent and affordable access to Low Earth Orbit.

This startup manufactures lithium-metal batteries using a composite membrane that replaces traditional ceramic separators, enabling large-area processing at a lower cost. Their technology increases energy density, addressing the limitations of current battery materials in terms of efficiency and production scalability.

VEIR is developing superconducting electric transmission lines that utilize a distributed, evaporative liquid nitrogen cooling system to achieve 5-10 times the transfer capacity of conventional lines. This technology increases grid capacity while minimizing siting and permitting challenges, addressing the urgent need for enhanced electricity transmission to support global decarbonization efforts.