Append Medical develops a transcatheter Left Atrial Appendage closure system that utilizes a proprietary vacuum mechanism to invert and ligate LAA tissue without implanting any devices in the heart. This approach significantly reduces the risks of device-related thromboembolism and peri-device leakage, addressing the heightened stroke risk faced by patients with non-valvular atrial fibrillation.

AtaCor Medical develops extravascular cardiac pacing and defibrillation lead systems that eliminate the need for transvenous access, reducing the risks and complications associated with traditional methods. Their technology enables reliable temporary pacing and defibrillation while allowing for safe patient ambulation post-procedure.

The startup develops surgical devices specifically designed for soft tissue surgery and hernia repair, utilizing techniques that optimize tissue tension and reinforcement. Their technology reduces tissue stress at the surgical site, minimizing the risk of surgical failure and enhancing patient outcomes.

First Light Diagnostics offers the MultiPath platform, a benchtop analyzer that performs culture‑free microbiology testing directly from patient specimens. It delivers pathogen identification in about 30 minutes and phenotypic antimicrobial susceptibility results within four hours, with an automated sample‑to‑answer workflow and HL7/FHIR integration for clinical laboratories and stewardship programs.

Trisol Medical develops a Transcatheter Tricuspid Replacement Valve designed to eliminate Tricuspid Regurgitation while preserving Right Ventricle function, addressing the needs of approximately 1.6 million patients in the U.S. who are unsuitable for surgical intervention. The valve features a nitinol frame and dome-shaped leaflet, allowing for easy implantation across various annulus sizes and providing a fully percutaneous solution.

VALFIX Medical is developing a transcatheter mitral valve repair system that enables cardiologists to perform minimally invasive procedures for patients suffering from severe functional mitral regurgitation. This technology provides a viable treatment option for millions of heart failure patients who are at high surgical risk and currently lack effective interventions.

VitalTech offers a full-stack enterprise solution that integrates virtual care coordination into existing healthcare workflows, enabling real-time monitoring and data analysis for improved patient outcomes. By providing actionable insights, the platform reduces emergency department visits and hospital readmissions, enhancing care efficiency and safety.