Top 50 Digital Therapeutics in Europe

The startup develops a digital therapeutics platform that utilizes machine learning to enable users to self-screen for dementia, providing accessible diagnostics and care. By integrating clinical research with digital solutions, the platform aims to mitigate the risk of dementia and enhance the quality of care available to patients.

Alex Therapeutics develops AI-integrated digital therapy companions that assist patients in managing complex treatment regimens and mental health challenges associated with cancer and rare diseases. Their evidence-based platform enhances patient adherence to medication and therapy, leading to improved health outcomes through behavior modification.

This startup develops B2B digital therapeutics software that operates on off-the-shelf Augmented Reality glasses, providing rehabilitation clinics with a wearable solution for both in-clinic and at-home therapy. The software enables clinics to enhance service scalability, improve patient access, and decrease neuro-rehabilitation treatment costs while reducing staff time by two-thirds.

HelloBetter provides evidence-based digital therapeutics for mental health, offering online therapy courses that are scientifically validated and available at no cost through prescriptions in Germany. The platform addresses issues such as anxiety, stress, and chronic pain by delivering structured programs guided by licensed psychologists, enhancing accessibility to mental health care for millions.

The startup has developed a digital therapy application that provides cancer patients with tailored information on diagnosis, treatment options, nutritional guidance, and relaxation techniques. This application supports patients in managing the complexities of their illness and enhances their overall well-being through accessible digital resources.

Prosoma develops a clinically validated digital therapeutic platform, Living Well, that provides psychological and behavioral support specifically for cancer patients. This solution effectively reduces symptoms of stress, anxiety, and depression, enhancing patients' emotional well-being and overall quality of life during their treatment journey.

The startup offers a personalized digital therapy platform that provides expert-led courses, self-management tracking, and clinical messaging for patients with inflammatory conditions. This system enables clinicians and patients to monitor health progress and gain tailored insights, improving daily health outcomes and long-term management of chronic illnesses.

Closed Loop Medicine develops personalized digital healthcare solutions that integrate dose-optimized drug therapy with digital therapeutics to enhance treatment adherence and patient outcomes. The platform addresses the inefficiencies of traditional healthcare delivery, which often leads to suboptimal management of chronic conditions and increased costs for payors.

Dawn Health develops regulated digital health products, including software as a medical device (SaMD) and digital therapeutics (DTx), to enhance chronic care management through patient empowerment and remote monitoring. Their platform accelerates the development and market entry of these solutions, improving patient adherence and outcomes while ensuring compliance with medical device regulations.

YLAH is a digital therapy platform that combines in-person psychotherapy with online therapeutic activities, facilitating a blended approach to mental health treatment. It addresses the challenge of fragmented therapy experiences by providing tools for professionals to efficiently plan, monitor progress, and engage patients between sessions.

Oto develops a digital therapy mobile application that utilizes cognitive behavioral therapy techniques to provide personalized audio sessions for tinnitus management. The program offers a structured approach to help users reduce the perception of tinnitus, achieving a 96% success rate in delivering measurable relief within 90 days.

GripAble develops digital therapy tools that utilize sensors to assess and train hand and arm movements, enhancing rehabilitation for physically impaired patients. By integrating engaging mobile games, GripAble improves patient adherence and outcomes while providing clinicians with objective progress tracking and documentation for optimal reimbursement.

Perfood develops a digital therapeutic platform that utilizes personalized low glycemic diet recommendations to help individuals prevent and manage diseases. By leveraging data-driven insights, the platform empowers users to make informed dietary choices that enhance their overall health and well-being.

Caspar Health offers a digital rehabilitation platform that combines personalized therapy with remote support from qualified healthcare professionals, ensuring continuous access to effective rehabilitation. This solution addresses the challenge of limited patient access to high-quality care by enabling clinics to provide multimodal aftercare while optimizing their specialist staff's workload.

Mindler provides a digital platform for immediate access to licensed psychologists through video consultations, enabling users to receive mental health support without wait times. The service addresses issues such as depression, anxiety, and stress by combining therapy sessions with interactive self-help exercises in a mobile app.

Rokoko Care offers a digital platform that enables physiotherapists to deliver evidence-based home rehabilitation through a mobile app, facilitating flexible training and real-time symptom tracking for patients. The platform enhances clinical decision-making by providing data-driven insights, allowing healthcare professionals to monitor patient progress and optimize treatment plans efficiently.

XR Therapeutics combines traditional Cognitive Behavioral Therapy (CBT) and Eye Movement Desensitization and Reprocessing (EMDR) with custom-built Extended Reality (XR) technology to provide targeted mental health interventions. This approach effectively addresses various anxiety disorders and PTSD, achieving a 94% success rate in positive treatment outcomes based on a decade of clinical research.

Monument Therapeutics utilizes digital biomarkers to identify patients with similar brain biology, enhancing the likelihood of effective responses to targeted treatments for cognitive impairment associated with schizophrenia and neuroinflammation. The company addresses the high failure rates of neuroscience drugs in clinical trials due to biological differences among patients by applying precision medicine principles to drug development.

The startup is developing a therapy assistant platform that utilizes a wearable device to monitor heart rate and machine learning algorithms to analyze users' emotional states. This technology aims to enhance mental health care by providing professionals with insights into the interactions between patients and therapists.

Braive provides an online platform for delivering evidence-based Cognitive Behavioral Therapy (CBT) programs, utilizing AI-driven diagnostic tools to create personalized treatment plans for patients. This approach addresses the inefficiencies in mental health care by significantly reducing documentation time and ensuring tailored support for clinicians and clients.

Affiniti AI is a virtual co-therapist that provides AI-driven support to clients between therapy sessions, enabling them to practice coping strategies and maintain engagement in their mental health journey. The platform offers tailored activities and insights to therapists, enhancing session effectiveness and ensuring alignment with treatment goals.

Restorative Neurotechnologies develops digital rehabilitation tools, including non-invasive neuromodulation and serious games, to enhance cognitive recovery for patients with neurological impairments. Their solutions address the challenges of traditional rehabilitation methods by improving patient engagement and monitoring cognitive health through cloud-based e-health software.

Mindgram is a science-based platform and mobile app that utilizes evidence-based therapeutic techniques to enhance mental wellness. It provides users with personalized mental health resources and tools to manage stress, anxiety, and emotional well-being effectively.

The startup develops AI-guided virtual reality software for behavioral health assessments and therapeutic exercises, specifically tailored for oncology and pain management departments. This tool streamlines conversational assessments and evidence-based interventions, improving treatment planning efficiency and enhancing patient outcomes.

Harp Health provides a digital platform for personalized musculoskeletal and pelvic care, utilizing remote video assessments and AI-assisted behavioral coaching to create tailored therapy and exercise plans. This solution addresses the challenges of accessing specialized care and maintaining adherence to treatment, improving recovery and pain management for users from the comfort of their homes.

Euleria develops digital rehabilitation devices that measure, monitor, and enhance patient mobility through remote and in-clinic solutions. Their technology provides healthcare professionals with objective assessments and personalized feedback, improving patient adherence and recovery outcomes.

Coco Care provides a digital platform for therapists to deliver evidence-based therapeutic interventions and personalized exercise programs to patients remotely. The platform enables remote patient monitoring and streamlines clinician workflow by automating progress tracking and documentation.

nyra health offers the myReha tablet app, a CE-certified medical device that provides customized therapy for patients with neurological deficits in language, memory, and cognition. The app supports both in-clinic and home-based rehabilitation, utilizing over 35,000 tasks to enhance daily living skills and improve patient outcomes.

The startup develops digital therapeutics that enhance brain health through personalized interventions delivered via smartphones. By integrating data from wearables, the platform enables users to monitor and improve cognitive function effectively.

Clareme utilizes Clinical Large Language Models (CLLM) to provide AI-driven self-therapy services, enabling users to engage in anonymous, judgment-free conversations for mental health support. This technology offers 24/7 access to clinically validated resources, helping individuals build resilience and improve their mental well-being without the need for human intervention.

Dara & Co develops an AI-powered digital wellbeing platform that provides personalized support for mental, emotional, and physical health through tailored recommendations and early interventions. The platform addresses the loneliness epidemic and mental health challenges by combining expert advice with real-life experiences to foster self-awareness, resilience, and community engagement.

Vitadio develops AI-driven digital therapeutics for type 2 diabetes, utilizing real-time feedback and personalized lifestyle modification to reverse insulin resistance. The platform enables users to achieve significant reductions in HbA1c and body weight, improving diabetes management without the side effects associated with traditional medications.

Oui Therapeutics is developing the world's first prescription digital therapeutic specifically designed to address suicide risk through evidence-based digital interventions. Their clinical trials aim to validate the efficacy of these therapeutics in reducing suicidal ideation and improving mental health outcomes.

Dana is a digital therapeutics platform that utilizes predictive intelligence and digital biomarkers to provide personalized mental health support for women during preconception, pregnancy, and early motherhood. The platform addresses the high rates of underdiagnosed and untreated mental health conditions, such as postpartum depression and anxiety, by offering tailored interventions and resources to improve maternal mental health outcomes.

AppThera is a digital therapeutics platform that enables healthcare providers to prescribe clinically validated mobile applications for managing chronic conditions such as diabetes and insomnia. By offering a streamlined selection of CE-marked therapies with proven efficacy, AppThera enhances patient adherence to treatment plans and improves overall quality of life.

Brain+ develops a digital Cognitive Stimulation Therapy (CST) platform that provides clinically validated, customizable activities to delay cognitive decline in dementia patients. This solution addresses the growing global dementia crisis by offering healthcare providers an effective, scalable method to enhance patient outcomes and improve quality of life.

The startup operates a digital therapeutics platform that provides audio-based psycho-educational content and mental health self-assessment tools specifically for women experiencing perinatal mental health disorders. By integrating consultation services and a community support network, the platform enables users to monitor and manage their mental well-being during the transition to motherhood.

Vantis provides a digital health platform that offers personalized treatment for chronic cardiovascular diseases through mobile applications, enabling patients to actively manage their care from home. The Vantis Heart App and Blood Pressure App are clinically validated solutions that significantly reduce systolic blood pressure and heart attack risk, available at no cost via prescription.

This startup develops AI-driven virtual reality rehabilitation games that utilize sensor technology to deliver high-intensity rehabilitation exercises in both clinical and home settings. By providing healthcare professionals with real-time data on patient progress and predictive recovery metrics, the platform enhances patient engagement and improves health outcomes.

The startup offers a digital physiotherapy platform that utilizes AI-driven assessments and real-time virtual sessions to provide personalized musculoskeletal care. This service enables immediate treatment and continuous adaptation to individual needs, eliminating traditional wait times and the necessity for in-person visits.

The startup develops a digital therapeutic technology that utilizes light stimulation to target specific photosensitive cells in the retina, modulating dopamine levels to regulate eye growth. This clinically validated therapy aims to slow the progression of myopia in children and adolescents.

eMoodie is a digital mental health platform that offers remote, evidence-based interventions and screening tools to improve access to mental health care. The platform enables users to receive personalized support from qualified professionals, eliminating the need for in-person visits and addressing the shortage of accessible mental health resources.

Moovd develops digital therapy solutions, including the WeMind platform, which utilizes EMDR (Eye Movement Desensitization and Reprocessing) techniques to enhance therapeutic outcomes. The platform improves session efficiency for therapists and accelerates symptom reduction for clients, evidenced by a 49% faster decline in subjective units of distress (SUD).

iATROS provides a digital health platform that utilizes telemedicine and machine learning to deliver real-time EKG assessments and personalized digital therapy plans for patients with cardiovascular diseases. The service connects users with healthcare professionals for remote consultations and monitoring, addressing the need for timely medical support and effective disease management.

SERG Technologies provides a digital therapeutics platform, PD.Ignite, that utilizes patented wearables and a centralized dashboard to monitor and manage Parkinson's Disease. This solution enables personalized care by adapting treatment plans based on real-time analytics, enhancing the quality of life for individuals with neurodegenerative movement disorders.

DiamPark develops digital neuromarker technology to capture and analyze data specific to Parkinson's disease, providing a reliable tool for real-time monitoring of disease progression and treatment efficacy. Their patient support program enhances therapeutic education and engagement, facilitating better communication between patients and healthcare providers.

Neuria develops digital interventions using gamified software to promote behavioral change and cognitive recovery, specifically targeting excessive consumption of unhealthy food, alcohol, and tobacco. Their evidence-based approach leverages patented technologies derived from neuroscientific research to facilitate large-scale public health improvements.

Eatit is a digital therapeutics platform that combines personalized dietitian consultations with medical weight loss treatments to support individuals with a BMI over 27 in achieving sustainable weight loss. The program offers tailored dietary plans and regular follow-ups through video or chat, addressing the challenges of chronic obesity with a comprehensive, individualized approach.

DyCare offers ReHub, a certified tele-rehabilitation platform that utilizes AI-driven personalized exercise prescriptions and real-time patient monitoring to enhance remote therapy effectiveness. This solution addresses the challenges of patient engagement and adherence in rehabilitation by providing automated progress tracking and detailed reporting for healthcare providers.

HealingHand Tech offers a digital rehabilitation game designed for stroke survivors, utilizing personalized treatment programs and gamified exercises to enhance upper limb recovery. This solution addresses the challenge of limited access to engaging and affordable rehabilitation, enabling patients to perform daily exercises remotely and track their progress effectively.