Top 50 Digital Therapeutics in Europe

The startup develops a digital therapeutics platform that utilizes machine learning to enable users to self-screen for dementia, providing accessible diagnostics and care. By integrating clinical research with digital solutions, the platform aims to mitigate the risk of dementia and enhance the quality of care available to patients.

Theremia develops advanced digital therapeutics designed to treat neurological and psychiatric disorders through personalized, non-invasive neuromodulation. The platform utilizes proprietary algorithms to deliver precise electrical stimulation, optimizing patient outcomes for conditions like depression and chronic pain. This approach offers a scalable, accessible alternative to traditional pharmacological interventions in mental healthcare.

HelloBetter provides evidence-based digital therapeutics for mental health, offering online therapy courses that are scientifically validated and available at no cost through prescriptions in Germany. The platform addresses issues such as anxiety, stress, and chronic pain by delivering structured programs guided by licensed psychologists, enhancing accessibility to mental health care for millions.

Alex Therapeutics develops AI-integrated digital therapy companions that assist patients in managing complex treatment regimens and mental health challenges associated with cancer and rare diseases. Their evidence-based platform enhances patient adherence to medication and therapy, leading to improved health outcomes through behavior modification.

Closed Loop Medicine develops personalized digital healthcare solutions that integrate dose-optimized drug therapy with digital therapeutics to enhance treatment adherence and patient outcomes. The platform addresses the inefficiencies of traditional healthcare delivery, which often leads to suboptimal management of chronic conditions and increased costs for payors.

Prosoma develops a clinically validated digital therapeutic platform, Living Well, that provides psychological and behavioral support specifically for cancer patients. This solution effectively reduces symptoms of stress, anxiety, and depression, enhancing patients' emotional well-being and overall quality of life during their treatment journey.

Dawn Health develops regulated digital health products, including software as a medical device (SaMD) and digital therapeutics (DTx), to enhance chronic care management through patient empowerment and remote monitoring. Their platform accelerates the development and market entry of these solutions, improving patient adherence and outcomes while ensuring compliance with medical device regulations.

YLAH is a digital therapy platform that combines in-person psychotherapy with online therapeutic activities, facilitating a blended approach to mental health treatment. It addresses the challenge of fragmented therapy experiences by providing tools for professionals to efficiently plan, monitor progress, and engage patients between sessions.

The startup offers a personalized digital therapy platform that provides expert-led courses, self-management tracking, and clinical messaging for patients with inflammatory conditions. This system enables clinicians and patients to monitor health progress and gain tailored insights, improving daily health outcomes and long-term management of chronic illnesses.

The startup has developed a digital therapy application that provides cancer patients with tailored information on diagnosis, treatment options, nutritional guidance, and relaxation techniques. This application supports patients in managing the complexities of their illness and enhances their overall well-being through accessible digital resources.

NowPatient Diabetes is a digital therapeutics application that enables personalized diabetes self-management through real-time health data tracking and tailored health insights. The platform provides users with actionable recommendations based on their individual health metrics, facilitating better control of their diabetes.

XR Therapeutics combines traditional Cognitive Behavioral Therapy (CBT) and Eye Movement Desensitization and Reprocessing (EMDR) with custom-built Extended Reality (XR) technology to provide targeted mental health interventions. This approach effectively addresses various anxiety disorders and PTSD, achieving a 94% success rate in positive treatment outcomes based on a decade of clinical research.

Restorative Neurotechnologies develops digital rehabilitation tools, including non-invasive neuromodulation and serious games, to enhance cognitive recovery for patients with neurological impairments. Their solutions address the challenges of traditional rehabilitation methods by improving patient engagement and monitoring cognitive health through cloud-based e-health software.

Psylaris develops virtual reality (VR) therapy solutions, including EMDR and exposure therapy, designed to enhance mental health treatment for therapists and their clients. By providing evidence-based tools that are already utilized by over 5,500 therapists, Psylaris addresses the need for effective and accessible mental health care.

Caspar Health offers a digital rehabilitation platform that combines personalized therapy with remote support from qualified healthcare professionals, ensuring continuous access to effective rehabilitation. This solution addresses the challenge of limited patient access to high-quality care by enabling clinics to provide multimodal aftercare while optimizing their specialist staff's workload.

The startup offers online therapy courses that utilize psychologically guided methods to provide anonymous and flexible treatment for individuals experiencing psychological stress and mental health disorders. By delivering structured programs, the company enables users to effectively manage symptoms of depression and other mental health issues.

The startup offers a therapy and coaching platform that connects patients with licensed therapists through secure video calls in Spanish, English, and Italian. This service provides affordable access to mental health care, promoting well-being while reducing the stigma associated with seeking help.

Virtuleap develops cognitive therapeutics utilizing virtual reality (VR) and artificial intelligence (AI) to address various health challenges. Their platform delivers immersive VR training modules designed to enhance executive function and emotional regulation in users. These solutions are applied across domains including mental wellness, addiction management, and supporting patients undergoing treatments like chemotherapy.

The startup is developing a therapy assistant platform that utilizes a wearable device to monitor heart rate and machine learning algorithms to analyze users' emotional states. This technology aims to enhance mental health care by providing professionals with insights into the interactions between patients and therapists.

NALU offers digital therapies utilizing evidence-based behavioral interventions to manage menstrual disorders. The platform provides users with personalized treatment plans that improve symptom management and enhance overall menstrual health.

The startup provides AI-driven personalized mental healthcare solutions that enable users to access tailored support based on their individual needs and preferences. This approach addresses the challenge of limited access to effective mental health resources, enhancing user engagement and outcomes.

PMHM develops medical products and digital services designed for the treatment of various diseases, utilizing evidence-based methodologies to enhance patient outcomes. The company focuses on improving treatment accessibility and effectiveness, addressing the challenges of disease management in healthcare settings.

Syntropic is developing a non-invasive, light-based therapy that enhances neuroplasticity by activating immune cells in the brain to promote healing and cognitive function. This technology aims to provide a cost-effective, side effect-free alternative for individuals suffering from psychiatric disorders, addressing the limitations of traditional antidepressant treatments.

Provides a therapeutic app that uses evidence-based behavioral activation techniques to improve cognitive health in individuals with mild cognitive impairment and early-stage dementia. The 12-week program helps users reduce memory loss, understand their brain health, and develop personalized routines to slow disease progression.

The startup provides a telemedicine platform that utilizes natural plant-based treatments, including personalized cannabis therapy, to manage chronic conditions such as pain, depression, and sleep disorders. Patients receive tailored medical assessments and treatment plans following consultations with licensed healthcare professionals, ensuring a focused approach to their specific health needs.

Sidekick is a digital care platform that utilizes personalized health management tools to support patients with chronic illnesses through tailored educational content and behavioral nudges. The platform enhances patient engagement and adherence to treatment plans, improving health outcomes and quality of life for individuals managing multiple conditions.

Strand Therapeutics develops programmable, long-acting mRNA therapeutics that utilize logic-based circuits to target and activate treatments specifically in diseased cells. This technology addresses the challenge of delivering precise, multi-functional therapies while minimizing off-target effects, aiming to improve treatment outcomes for cancer and other life-threatening diseases.

The startup offers a telemedicine platform that utilizes artificial intelligence to analyze patient responses and facilitate online consultations with healthcare professionals. This service addresses the need for accessible medical advice and prescription delivery, allowing users to manage their health without visiting a clinic.

Tepy is a digital platform that offers virtual physiotherapy through data-driven assessments and personalized rehabilitation programs for individuals with physical injuries. The platform provides accessible and effective recovery solutions by delivering tailored exercise regimens that enhance rehabilitation outcomes.

XtalPi is a pharmaceutical technology company that utilizes computational modeling and machine learning to predict drug interactions and properties, followed by experimental validation in wet labs. This approach reduces the time and cost associated with traditional drug discovery processes, enabling faster development of effective therapeutics.

ADmit Therapeutics is developing a diagnostic test that identifies biomarkers unrelated to β-amyloid and tau for the early detection of Alzheimer's disease. This technology aims to facilitate timely diagnosis, enabling earlier intervention and improved patient outcomes.

This startup utilizes real-world evidence generation and advanced data analytics to provide actionable insights for healthcare decision-making. It addresses the lack of sufficient clinical and market evidence, improving the effectiveness of treatments and interventions.

BluTapp offers remote treatment for PTSD through the use of bilateral stimulation techniques, enabling patients to engage in therapy from their own homes. This approach provides accessible mental health support for individuals experiencing trauma-related symptoms.

The startup offers a digital sexual therapy application that utilizes algorithm-driven assessments to identify sexual dysfunction and create personalized treatment plans. This platform enables users to engage in therapy independently, making sexual health support affordable and accessible without the stigma often associated with traditional therapy.

The startup develops AI-guided virtual reality software for behavioral health assessments and therapeutic exercises, specifically tailored for oncology and pain management departments. This tool streamlines conversational assessments and evidence-based interventions, improving treatment planning efficiency and enhancing patient outcomes.

MyReha provides an AI-powered digital neurotherapy ecosystem for patients, clinics, and practices managing neurological disorders. The platform offers personalized, evidence-based therapy programs via a mobile application and integrates management tools for professionals. This solution aims to deliver effective, accessible rehabilitation support for speech, memory, and cognitive skills.

Vitadio develops AI-driven digital therapeutics for type 2 diabetes, utilizing real-time feedback and personalized lifestyle modification to reverse insulin resistance. The platform enables users to achieve significant reductions in HbA1c and body weight, improving diabetes management without the side effects associated with traditional medications.

BIOS Health develops neural interfaces and AI technology to read and write neural data, enabling real-time analysis of the nervous system's signals. This approach addresses the malfunctioning signals that can lead to diseases, facilitating the creation of targeted pharmaceuticals and software-delivered therapies.

GripAble develops digital therapy tools that utilize sensors to assess and train hand and arm movements, enhancing rehabilitation for physically impaired patients. By integrating engaging mobile games, GripAble improves patient adherence and outcomes while providing clinicians with objective progress tracking and documentation for optimal reimbursement.

The startup operates a personalized rehabilitation platform that utilizes medical-grade mobile applications to facilitate patient recovery post-surgery. By providing tailored rehabilitation programs, the platform enhances patient engagement and accelerates the healing process.

CUREosity provides virtual reality therapy solutions that enhance patient engagement through immersive experiences tailored for mental health treatment. The platform equips healthcare providers with tools to deliver effective and accessible therapeutic interventions, addressing the growing demand for improved mental health care options.

The startup develops a digital therapeutic technology that utilizes light stimulation to target specific photosensitive cells in the retina, modulating dopamine levels to regulate eye growth. This clinically validated therapy aims to slow the progression of myopia in children and adolescents.

SERG Technologies provides a digital therapeutics platform, PD.Ignite, that utilizes patented wearables and a centralized dashboard to monitor and manage Parkinson's Disease. This solution enables personalized care by adapting treatment plans based on real-time analytics, enhancing the quality of life for individuals with neurodegenerative movement disorders.

This startup provides telemedicine services and therapy options focused on medicinal cannabis, enabling patients to receive personalized treatment plans from a network of specialized physicians. By facilitating remote consultations and tailored therapies, the company enhances patient access to effective healthcare solutions.

The startup operates a digital therapeutics platform that provides audio-based psycho-educational content and mental health self-assessment tools specifically for women experiencing perinatal mental health disorders. By integrating consultation services and a community support network, the platform enables users to monitor and manage their mental well-being during the transition to motherhood.

The startup develops digital therapeutics that enhance brain health through personalized interventions delivered via smartphones. By integrating data from wearables, the platform enables users to monitor and improve cognitive function effectively.

The startup operates a coordinated care pathway for mental health conditions, utilizing evidence-based treatment protocols for stress, anxiety, depression, and autism. This approach enables patients to receive tailored and efficient treatment plans that improve their overall mental health outcomes.

EnClear Therapies utilizes its proprietary EnTrega CSF Platform to deliver precision dosing of therapeutics directly to the central nervous system, minimizing severe side effects and peripheral toxicity. The company focuses on treating neuro-oncology and expanding into neurodegenerative, lysosomal storage, and autoimmune diseases, addressing the critical need for effective CNS disease management.

Medea Mind is a clinical software solution designed for mental health professionals that automates patient management and enhances communication through data-driven insights. By utilizing biopsychosocial assessments and intelligent algorithms, it streamlines treatment planning and monitoring, improving patient adherence and clinical outcomes.

Vantis provides a digital health platform that offers personalized treatment for chronic cardiovascular diseases through mobile applications, enabling patients to actively manage their care from home. The Vantis Heart App and Blood Pressure App are clinically validated solutions that significantly reduce systolic blood pressure and heart attack risk, available at no cost via prescription.