Top 50 Desalination Technology - Late Stage

This startup develops low-cost handheld seawater desalination devices for humanitarian and marine applications, providing a reliable source of potable water in areas facing freshwater scarcity. Additionally, the company offers grid-scale energy storage and clean electricity solutions, enhancing energy accessibility while promoting sustainability.

ACWA Power develops and operates a diverse portfolio of power generation facilities, focusing on renewable energy sources such as solar and wind. The company addresses the need for sustainable energy solutions by providing reliable electricity while reducing carbon emissions in the power sector.

Generate provides a full‑stack platform that designs, finances, builds, owns, and operates utility‑grade energy, water, and waste assets such as battery storage, distributed solar, EV charging, desalination, and organic waste treatment. Customers—including municipalities, corporate campuses, and enterprises—access these resources via off‑balance‑sheet PPAs, leases, or service contracts, receiving fixed‑price service, real‑time IoT monitoring, AI‑driven performance analytics, and integrated ESG reporting without upfront capital or technical risk.

Gradiant provides integrated water‑treatment platforms for large industrial facilities, combining membrane, adsorption, oxidation and extraction technologies to reduce freshwater intake and recover metals, minerals and other resources. The systems include an AI‑driven SmartOps analytics layer and proprietary CURE chemicals that continuously optimize process setpoints, predict maintenance and ensure compliance for applications such as zero‑liquid‑discharge, PFAS destruction, lithium extraction and electrolyzer‑ready water.

NuScale Power has developed a small modular reactor (SMR) designed for efficient electrical generation and thermal applications. This technology provides a scalable and reliable energy solution to meet the growing demand for low-carbon power sources.

RePG Energy utilizes patented technology to generate electricity and potable water from latent heat and waste heat sources, employing principles of osmosis and diffusion without the need for turbines or generators. This system addresses energy inefficiency and water scarcity by enabling decentralized energy production and water generation in residential, industrial, and mobile applications.

Commercializes a Hybrid Direct Air Capture (HDAC) system that captures CO2 and harvests water from ambient air using only electricity and solid sorbents, eliminating the need for water and heat. This approach reduces energy consumption and operational costs, enabling deployment in water-scarce regions while producing water as a byproduct. The HDAC system offers the lowest Levelized Cost of Capture in the direct air capture market.

Lilac Solutions has developed a patented ion exchange technology that extracts lithium from brines with ultra-low freshwater usage and high tolerance for impurities, eliminating the need for evaporation ponds. This technology enables lithium producers to efficiently access and process lithium from diverse brine sources, addressing the industry's demand for sustainable and cost-effective extraction methods.

Summit Nanotech utilizes patented direct lithium extraction technology to efficiently extract high-purity lithium from brine, significantly reducing production time from 18 months to just one day. This process addresses the increasing global demand for lithium in electric vehicle batteries while minimizing environmental impact by reinjecting lithium-depleted brine back into the source.

Tidal Vision manufactures chitosan-based biomolecular solutions using its proprietary Chitofining™ Process and Zale Technology™ to address water treatment and agricultural challenges. Their products enhance efficiency and reduce environmental impact by providing high-concentration, zero-waste alternatives to traditional chemical solutions.

Moleaer develops industrial-scale nanobubble systems that enhance oxygen transfer rates in water treatment and agricultural processes, improving chemical reactions and water quality. Their technology enables more efficient irrigation and aquaculture by increasing dissolved oxygen levels, which promotes plant health and reduces operational costs.

EnergyX utilizes patented Direct Lithium Extraction technologies to efficiently convert brine into high-purity lithium products, addressing the global supply shortage of this critical resource. The company's advancements in lithium refining and battery innovation support the growing demand for sustainable energy storage solutions in electric vehicles and renewable energy systems.

Allonnia develops biotechnological solutions to remediate emerging contaminants such as PFAS and 1,4-dioxane using proprietary microbial systems and innovative separation technologies. Their methods enable the detoxification of contaminated water, aiming to treat over 600 billion gallons by 2040 while enhancing sustainable practices in the metals and mining industries.

This startup provides treatment processes for natural gas and produced water in the oil and gas industry, utilizing automated control and data collection technologies for H2S gas, acid gas, and produced water treatment. Their systems enable firms to meet environmental regulations while minimizing human intervention and enhancing the reusability of water resources.

Ohmium manufactures proton exchange membrane (PEM) electrolyzers that convert water and renewable energy into high-purity green hydrogen, addressing the need for sustainable energy solutions across various industries. Their modular systems enable scalable hydrogen production, enhancing operational efficiency and supporting decarbonization efforts in power, transportation, and industrial applications.

Haber provides a real-time automation platform that utilizes AI-driven algorithms and robotic sampling to monitor and control process, utilities, and water systems. This technology enhances operational efficiency by reducing chemical consumption, minimizing variability, and improving output quality in industrial settings.

Outset Medical is a medical technology company that has developed a portable dialysis system designed to enhance patient comfort and accessibility. This technology addresses the challenges of traditional dialysis by enabling patients to receive treatment in various settings, thereby improving their quality of life and reducing the burden on healthcare facilities.

280 Earth manufactures Direct Air Capture (DAC) systems that extract CO2 from the atmosphere, addressing the excess carbon levels that have risen from 280 to 425 parts per million since industrialization. Their facility in The Dalles, Oregon, is designed to capture over 20,000 tons of CO2 annually, contributing to long-term climate improvement and sustainable carbon removal solutions.

The startup develops an artificial intelligence-based leak detection and auto-shutoff system that identifies and stops water leaks at their source. This technology prevents water damage from leaks and broken pipes, enabling organizations to conserve water and reduce carbon emissions associated with water waste.

Verdagy develops a patented single-cell electrolyzer technology that enables efficient, large-scale production of green hydrogen by pairing with variable energy sources. This approach addresses the high operational costs and inflexibility of traditional electrolysis methods, delivering the lowest levelized cost of hydrogen in the industry.

This startup manufactures climate technology products that utilize advanced carbon capture and energy efficiency systems to reduce greenhouse gas emissions. By providing measurable solutions, the company enables clients to meet their sustainability targets and contribute to global climate initiatives.

H2Pro develops a decoupled, membraneless electrolysis method for green hydrogen production, significantly reducing costs and enhancing operational flexibility. This technology addresses the need for affordable, scalable green hydrogen to support renewable energy integration and achieve net-zero emissions.

Enapter manufactures hydrogen generators using patented Anion Exchange Membrane (AEM) technology, enabling efficient production of green hydrogen from renewable energy sources. Their modular AEM Electrolysers, ranging from 2.4 kW to 100 MW, facilitate scalable hydrogen production while optimizing energy management through an integrated software toolkit.

GeoPura utilizes renewable energy sources, such as solar and wind, to produce green hydrogen through water electrolysis, enabling the generation and distribution of zero-emission electricity. This technology provides a sustainable alternative to fossil fuels, facilitating the decarbonization of various industries and helping organizations achieve their net-zero targets.

Lygos produces bio‑manufactured specialty polymers, including the Soltellus™ family, from renewable sugars and CO₂. These biodegradable, water‑soluble polymers act as performance boosters, super‑absorbents, and scale inhibitors for agronomy, home‑care, hygiene, personal‑care, and water‑treatment formulations, enabling customers to replace persistent chemicals without sacrificing efficacy or cost. Lygos also supplies technical documentation and collaborative formulation support to accelerate product development.

Bevi develops a smart water dispenser that connects to a building's water supply, providing customizable still and sparkling beverages using a specialized carbon filtration system. This technology eliminates the need for single-use plastic bottles and cans, saving an average of 50,000 containers annually per machine while offering a healthier hydration option with zero- and low-calorie flavors.

Hysata develops hydrogen electrolyzers that utilize advanced membrane technology to efficiently convert water into green hydrogen, addressing the reliance on fossil fuels for energy. Their electrolyzers aim to lower production costs and increase the scalability of green hydrogen, facilitating a transition to sustainable energy sources.

Stargate Hydrogen Solutions provides turn-key alkaline electrolysis systems for the production of green hydrogen using renewable energy sources. Their technology addresses the need for decarbonization in industries such as heavy transport and steelmaking, where traditional electrification methods are insufficient.

H2SITE utilizes palladium-alloy membrane reactors to extract high-purity hydrogen from easily transportable feedstocks like ammonia and methanol, achieving over 99% purity and up to 98% recovery efficiency. The company addresses the challenge of high costs and inefficiencies in long-distance hydrogen transport, enabling small and medium enterprises to access low-carbon hydrogen more affordably.

Syzygy Plasmonics develops a photocatalytic reactor that utilizes light to produce hydrogen and syngas from low-carbon-intensity feedstocks, eliminating the need for combustion in chemical production. This technology addresses the high carbon emissions associated with traditional fossil fuel-based chemical processes, enabling a more sustainable and cost-effective approach to fuel production.

Heliogen develops concentrating solar energy and thermal storage systems that provide carbon-free heat, steam, or power for industrial operations. Their AI-powered technology delivers reliable, round-the-clock clean energy solutions to decarbonize heavy industry.

Electric Hydrogen builds large‑scale alkaline electrolyzer systems that convert electricity to hydrogen with over 80 % round‑trip efficiency at pressures up to 30 bar. The modular, 10 MW‑scalable hardware includes an integrated digital control platform for real‑time monitoring, predictive maintenance, and rapid integration with renewable power and existing hydrogen infrastructure. This turnkey solution lowers capital and operating costs for heavy‑industry and utility customers seeking to replace gray hydrogen with green production.

The startup develops high-power hydrogen fuel cells that utilize electrochemical conversion of hydrogen-containing fuels for sustainable power generation. This technology enables the transportation and power industries to reduce carbon emissions and transition to cleaner energy sources.

Solugen operates a sustainable molecule factory that utilizes engineered enzymes and metal catalysis to convert plant-derived feedstocks into essential chemical building blocks, significantly reducing emissions and waste. This technology replaces traditional petroleum-based products, addressing the environmental impact of chemical manufacturing in various industries, including energy, agriculture, and personal care.

The startup develops lightweight pressure control equipment, including gas and fluid pressure regulators, to enhance the reliability of conventional valve systems. Their technology simplifies water distribution systems, ensuring consistent potable water supply while meeting stringent water quality and leakage control standards, ultimately reducing operational costs for energy, water, and process industries.

Panthalassa harnesses oceanic energy through advanced marine technology to generate low-cost, renewable power for offshore computing and sustainable fuel production. This approach addresses the global demand for clean energy while utilizing the ocean's vast renewable resources.

Quanta Dialysis Technologies provides an FDA‑cleared hemodialysis platform that supports home, in‑center, SLED, and CRRT treatments on a single compact device. By generating dialysate on demand, it eliminates disposable bags, daily rinses, and chemical disinfection, reducing waste and maintenance while simplifying setup across hospitals, dialysis centers, and home‑care settings.

This company designs and deploys liquid-cooled datacenter infrastructure optimized for high-density computing workloads. Their solutions reduce operational costs, minimize environmental footprint through lower energy and water usage, and accelerate deployment timelines. They provide end-to-end capabilities for building efficient, scalable, and sustainable data facilities.

N-Drip has developed a gravity-powered micro-irrigation system that utilizes existing field infrastructure to deliver precise irrigation without the need for pumps or filters. This technology significantly reduces water usage in agriculture, addressing the inefficiencies of traditional flood irrigation, which wastes up to 70% of water resources.

Elicit Plant develops phytosterol-based solutions that enhance crop resilience to drought by improving water management and reducing consumption by 20%. Their technology enables maize, wheat, and sunflower crops to maintain yields during water shortages, addressing the challenges posed by climate change and water scarcity.

Verdox has developed an electrochemical carbon removal technology that captures carbon dioxide directly from the air and industrial emissions using only electricity, significantly reducing energy consumption by up to 70%. This technology addresses the challenge of high emissions in aluminum production and other sectors, enabling organizations to meet their decarbonization targets efficiently.

Syensqo develops chemical solvents tailored for industries such as aerospace, automotive, food, and agriculture, focusing on enhancing operational efficiency and sustainability. Their products address the need for environmentally friendly solutions that minimize harmful emissions and improve safety in industrial applications.

Quaise is developing a gyrotron-powered drilling platform that utilizes millimeter-wave technology to vaporize boreholes and access deep geothermal energy at depths of up to 20 kilometers and temperatures of 500°C. This approach enables the rapid deployment of clean, renewable energy by repurposing existing fossil fuel infrastructure, addressing the urgent need for scalable and sustainable energy solutions.

Koloma utilizes advanced geological surveying and data analytics to locate and extract geologic hydrogen resources, providing a sustainable energy source. This approach addresses the need for low-cost, low-carbon alternatives in the global energy transition.

Blue World Technologies manufactures methanol fuel cells that provide a green alternative to combustion engines and diesel generators, specifically targeting hard-to-abate sectors like maritime and heavy-duty transportation. Their technology enables fuel savings of 20-30% and up to 100% CO2 recovery, facilitating a cost-effective transition to renewable energy sources.

Helion is developing a patented plasma accelerator technology for magneto-inertial fusion, producing fifty-megawatt modules that generate zero-carbon electricity. This technology provides a low-cost and safe energy solution to meet the increasing demand for clean energy while minimizing environmental impact.

CarbonCapture Inc. develops modular direct air capture (DAC) systems that utilize solid sorbents to extract over 500 tons of CO₂ from the atmosphere annually per unit. Their technology addresses climate change by enabling large-scale carbon removal and permanent geological storage of captured CO₂.

Marvel Fusion pioneers laser-driven inertial confinement fusion to generate abundant, clean energy. This approach utilizes high-power, ultra-short pulse lasers and non-cryogenic fuels to initiate fusion reactions. The company is developing this technology to deliver sustainable fusion power to the grid by the mid-2030s.

Mura Technology employs a proprietary chemical recycling process to convert plastic waste into its original monomers, facilitating the production of new plastics without relying on virgin materials. This method significantly reduces plastic waste in landfills and decreases the carbon emissions associated with conventional plastic manufacturing.

Eavor utilizes its proprietary Eavor-Loop™ technology to provide a closed-loop geothermal energy system that generates clean, baseload power without the environmental risks associated with traditional geothermal methods. This solution addresses the need for reliable, carbon-neutral energy by eliminating issues such as fracking, water use, and aquifer contamination.