Top 50 Chemical Manufacturing in Japan

Solaris Bio develops serum-free culture media and related solutions for cell manufacturing in regenerative medicine, utilizing proprietary AI technology to enhance the safety and efficacy of cell products while reducing costs. The startup addresses the need for chemically defined and animal origin-free media formulations that optimize cell growth and differentiation for various therapeutic applications.

This startup manufactures architectural components using large-scale 3D printing technology with recycled plastic materials, specifically producing concrete formwork and interior/exterior panels. By providing sustainable building materials, the company addresses the labor shortage in construction and enhances resource recycling in the industry.

TIER IV develops autonomous driving technology for intelligent vehicles, utilizing advanced sensor fusion and machine learning algorithms to enhance navigation and safety. This technology addresses the need for efficient transportation solutions, improving mobility and quality of life in urban environments.

QunaSys develops quantum algorithms and software tools, such as the QURI SDK, to enhance the practical application of quantum computing in industries like materials science, chemistry, and pharmaceuticals. The company collaborates with businesses and research institutions to optimize computational processes, enabling them to tackle complex industrial challenges more efficiently.

This startup develops fusion technology that includes liquid metal and molten salt systems, tritium treatment, and high-frequency microwave gyrotrons for commercial fusion reactors. Their solutions aim to enable companies to generate fusion energy, thereby eliminating carbon dioxide emissions from traditional energy sources.

The startup develops metal-free catalytic electrodes and electrolysis catalysts to enhance the efficiency and cost-effectiveness of green hydrogen production. Their technology addresses the resource constraints associated with traditional catalysts, promoting a sustainable energy ecosystem and facilitating a recycling-oriented society.

OOYOO develops gas separation membranes specifically designed for the efficient capture of carbon dioxide and hydrogen from industrial emissions. This technology addresses the need for effective carbon capture solutions to support the transition to a carbon-neutral society.

The startup operates a research platform focused on the design and manufacturing of topological materials derived from quantum science, along with associated software for devices utilizing these materials. This technology enhances energy efficiency and sustainability in various applications, enabling businesses to optimize energy utilization.

bitBiome utilizes single-cell sequencing technology to catalog and evolve microbial genomes, creating a diverse database of over 2 billion sequences. This platform addresses the need for unique enzymes and proteins to enhance biomanufacturing processes across various industries, including drug production and sustainable materials development.

The startup manufactures single-crystal piezoelectric materials and devices using proprietary technology to produce high-quality single-crystal layers. This technology addresses the challenge of epitaxial multiple layers, providing semiconductor industries with reliable and efficient semiconductor devices.

The startup develops all-polymer lithium-ion batteries designed for large-scale energy storage in renewable energy systems, such as wind and solar power. These batteries offer high energy density and enhanced safety, enabling efficient management of distributed energy resources while reducing costs for enterprises.

The startup has developed a resource-recycling platform that utilizes underutilized natural biomass and photosynthetic organisms to produce industrial biopolymers, nitrogen fertilizers, and aquaculture feed. This technology provides sustainable alternatives for greenhouse gas fixation, enabling environmental startups to access eco-friendly products efficiently.

Braid develops software that integrates mathematics, physics, and computer science to optimize product design for performance-critical applications while utilizing ecological materials. The company accelerates the product development process from concept to final design, enabling manufacturers to reduce material usage and enhance sustainability without compromising functionality.

M2X is a digital application that streamlines equipment maintenance in manufacturing facilities by automating record-keeping and data analysis through mobile devices. This solution reduces time spent on manual paperwork and enhances operational visibility, leading to improved productivity and equipment uptime.

The startup develops spherical sensors and analyzers for chemical sensing, utilizing advanced sensor technology to detect moisture, hydrogen, and other environmental attributes at the nanoscale. Their products enable real-time identification of various gases, addressing the need for high-speed and highly sensitive environmental monitoring solutions.

Ac-Planta develops and manufactures biostimulant materials that enhance plant growth and resilience by utilizing natural microbial and organic compounds. Their products address nutrient deficiencies and improve crop yields, contributing to sustainable agricultural practices.

Alivexis develops custom biopharmaceutical solutions through advanced genetic engineering and personalized medicine techniques, addressing the need for tailored therapies in the pharmaceutical industry. The company focuses on optimizing drug efficacy and safety by creating treatments that are specifically designed to meet individual patient profiles.

This startup provides research and development services for smart factory systems that utilize artificial intelligence to automate machining operations and industrial IoT to monitor factory performance. The company addresses the technician shortage by enhancing operational efficiency and enabling real-time data-driven decision-making in manufacturing environments.

Fermenstation utilizes proprietary fermentation technology to convert unused biomass into low-carbon, regenerative ingredients for various industries, including cosmetics and homecare products. By upcycling food waste and industrial byproducts, the company creates a zero-waste production system that supports a circular economy and sustainable resource management.

Carbon Fly specializes in the research, development, and mass production of high-quality carbon nanotubes, addressing the challenges of cost and stable supply in various industries such as energy, aerospace, and construction. By transforming carbon dioxide into a resource, the company contributes to a carbon-neutral society and supports sustainable development goals.

AC Biode develops chemical catalysts for the depolymerization of plastic waste at low temperatures, transforming it into usable oil feedstock. The company also captures CO2 from the air to produce glass, addressing the dual challenges of plastic pollution and carbon emissions.

The startup offers an online education platform that fosters a community for students and professionals to explore and express their personalities through tailored interactions. By creating a supportive environment, users can connect with like-minded individuals and enhance their learning experiences based on shared interests.

The startup develops a design algorithm that leverages metamaterials to create complex product features such as motion and elasticity, which are challenging to achieve through traditional design methods. This platform enables users to directly integrate functional properties with product shape and material specifications, streamlining the design process and enhancing manufacturability.

ARCHAIVE is an AI-powered drawing management system for manufacturers that uses advanced search and automated difference detection to streamline operations. It centralizes drawing data with metadata, enabling faster access to information and improving quoting and production efficiency.

Sigmai employs quantum annealing technology to optimize resource allocation and production scheduling in manufacturing processes. By enhancing operational efficiency, the company helps businesses reduce costs associated with complex problem-solving challenges.

The startup manufactures hybrid rocket engines utilizing solid plastic fuel and liquid oxidizer, designed for mass production to lower costs. This technology enables broader access to space travel by simplifying rocket manufacturing and enhancing safety.

Relectra provides hardware solutions that enhance design efficiency and lower production costs through a robust procurement network and engineering expertise. The startup focuses on optimizing supply chain operations for clients in manufacturing, ensuring reliable sourcing and streamlined processes.

The startup develops soft robotics equipment, including pneumatic artificial muscles and peristaltic pumps, to enhance flexibility and efficiency in sustainable manufacturing processes. Their technology enables companies to perform tasks such as fluid mixing, pipe inspection, and upper arm assistance with lightweight, multipurpose solutions.

WEAD develops biodegradable materials and additives that accelerate the decomposition of organic waste and bioplastics, significantly reducing their breakdown time from months to days. By transforming discarded materials into valuable products, the company addresses the growing issue of waste management and environmental sustainability.

The startup offers digital experience software that enhances user engagement through real-time analytics and personalized content delivery. This technology addresses the challenge of low customer retention by providing actionable insights that help businesses tailor their digital interactions.

This startup develops AI-driven robotics technology to automate repetitive tasks and heavy labor in the food, cosmetics, and pharmaceutical sectors, where labor shortages are prevalent. By implementing these robots, businesses can enhance productivity and efficiency in environments that are traditionally challenging to automate.

Tokyo Factory offers a cloud-based process control system that visualizes manufacturing data across the supply chain, enabling the construction of a centralized manufacturing information database. This service enhances operational efficiency, facilitates skill transfer, and improves delivery timelines and product quality while reducing travel costs.

The startup develops nucleic acid-based adjuvants and primers for PCR genetic testing, utilizing blocker-based oligonucleotide synthesis technology to produce high-purity oligonucleotides at scale. This capability enables pharmaceutical companies to enhance the development of therapeutics by providing reliable and efficient nucleic acid APIs.

The startup develops greenhouse gas calculation software that integrates with enterprise resource planning (ERP) systems to automatically quantify emissions across the entire supply chain. This technology enables companies to monitor their carbon footprint and implement strategies for emissions reduction while also providing consulting for climate change risk management.

The startup provides a platform that enhances procurement strategies for major manufacturers by facilitating digital transformation and optimizing sourcing processes. This technology enables manufacturers to achieve cost reductions through improved procurement efficiency and execution support.

The startup develops an inventory strategy model that utilizes process data modeling and optimization techniques to determine optimal inventory levels in manufacturing. This approach enhances productivity and profitability by enabling manufacturers to manage their inventory more effectively, thereby reducing excess stock and improving supply chain efficiency.

KM Biologics specializes in the research, production, and distribution of human and animal vaccines, as well as plasma fractionation products, utilizing advanced biopharmaceutical manufacturing techniques. The company addresses the critical need for effective immunization solutions and therapeutic products to combat infectious diseases and improve public health outcomes.

This startup manufactures upcycled materials from plant residues, such as sugarcane bagasse, converting them into paper thread as a sustainable alternative to environmentally harmful materials. By enabling industries to effectively reuse limited resources, the company contributes to the reduction of waste and promotes a circular economy.

NuFlare Technology provides advanced semiconductor manufacturing equipment, including electron beam mask writers and mask inspection systems. Their solutions enable the precise creation and verification of photomasks essential for producing leading-edge integrated circuits.

Crafton Biotechnology develops and synthesizes high-quality mRNA for pharmaceutical applications, focusing on creating new drugs for diseases with significant medical needs. By collaborating with universities and pharmaceutical companies, they enhance their mRNA platform technology to expedite the delivery of effective treatments.

This bio-hybrid company develops sustainable fabric care products by combining traditional Indian knowledge with nanotechnology. Their eco-friendly solutions enhance fabric performance and longevity, offering the textile industry a way to minimize environmental impact.

This startup operates an online marketplace that connects Japanese manufacturing technologies with businesses seeking relevant technological partnerships. By facilitating access to diverse manufacturing processes, the platform addresses the challenge of sourcing specialized technology for hardware developers and manufacturers.

Water Design Japan manufactures ultrafine bubble-generating nozzles using specialized technology that creates microbubbles for enhanced water treatment and cleaning applications. This technology improves the efficiency of processes such as wastewater treatment and surface cleaning by increasing the surface area of bubbles, leading to better contaminant removal.

The startup develops 3D air floating image technology products that utilize nanotechnology, laser processing, and optical design to create precise mold designs and ultra-fine processing on curved surfaces. This technology enables manufacturers to efficiently prototype and implement innovations inspired by natural processes, enhancing production capabilities and reducing time-to-market.

Helicity develops software systems utilizing fluid simulation, scientific computing, and AI technologies to enhance operational efficiency in the construction and manufacturing sectors. The company addresses challenges in data processing and simulation, enabling clients to optimize workflows and improve decision-making through advanced computational methods.

CADDi is an AI-driven data platform that automates the analysis of 2D drawings and streamlines supplier selection for manufacturing procurement. By structuring design data and enhancing cost management, CADDi reduces operational inefficiencies and enables manufacturers to focus on more creative tasks.

LIPPER develops a sustainable tire reinforcement additive made from natural materials like nanocellulose and bio-silica. This biotechnology-based solution replaces petroleum-derived carbon black, aiming to significantly reduce CO2 emissions and microplastic pollution from tire production and wear.