Top 50 Chemical Manufacturing in Ireland

Produces green hydrogen using solar-powered electrolysis, converting water into hydrogen without carbon emissions. This technology addresses the need for sustainable and affordable hydrogen production, supporting the transition to a low-carbon energy system.

Elementra provides an AI‑native ERP platform that continuously ingests demand, supplier and shop‑floor data to generate real‑time forecasts, production schedules and replenishment actions. Its context‑aware software agents operate in a human‑in‑the‑loop mode, enabling manufacturers to reduce safety stock, avoid stockouts and improve equipment effectiveness.

Brightbeam is a full‑service AI partner that designs, builds, and embeds production‑grade AI solutions into the core workflows of large, regulated enterprises. It provides end‑to‑end implementation, MLOps automation, and compliance‑focused governance to turn prototypes into reliable, continuously monitored assets, enabling an AI‑native culture across sectors such as biopharma, advanced manufacturing, and insurance.

Nemysis develops a nano-particulate iron supplement, Iron Hydroxide Adipate Tartrate (IHAT), that mimics natural iron absorption to reduce gastrointestinal side effects commonly associated with traditional iron supplements. The company also creates an endoprotease, E40, which breaks down gluten peptides to alleviate discomfort for patients with Coeliac Disease and Non-Celiac Gluten Sensitivity.

The startup operates a research lab that utilizes low-temperature hydrometallurgical processes to extract lithium, cobalt, nickel, and manganese from spent lithium-ion batteries and black mass. This technology enables clients to recycle battery materials more sustainably, significantly lowering carbon emissions compared to traditional recycling methods.

XFuel transforms diverse waste streams into affordable, low-carbon drop-in transport fuels. The company is also developing sustainable, carbon-negative fuels for future energy needs. This process provides a viable pathway for decarbonizing existing transportation infrastructure.

This startup develops smart manufacturing technologies that integrate data analytics, robotics, and process control to enhance operational efficiency in industrial settings. By providing advanced simulation and modeling tools, the company enables manufacturers to optimize production processes and improve product quality.

The startup specializes in the research and development of naturally occurring small molecules that enhance cellular regeneration and clear cellular debris, which are critical for maintaining healthy aging. By focusing on the production routes of these molecules, the company provides healthcare researchers with tools to support anti-aging mechanisms at the cellular level.

The startup develops performance management software for the pharmaceutical and biotech manufacturing sectors, featuring a dashboard that integrates site-specific KPIs and intelligent workflows. This technology eliminates the need for repetitive data tracking, enabling facilities to enhance process performance and operational efficiency.

ETFuels is developing an off-grid green fuel production model that utilizes renewable energy to create commercially viable green fuels for heavy industry. This approach aims to decarbonize entire economies and supply chains, addressing the urgent need for sustainable energy solutions in Europe.

Blynkdesign provides a Digital Knowledge Twin platform that enables pharmaceutical manufacturers to create a unified, traceable representation of their manufacturing processes. This technology addresses the challenges of fragmented knowledge and inefficiencies, resulting in reduced time to market, minimized errors, and improved audit readiness.

Precisement specializes in developing and deploying advanced robotic systems for industrial automation. The company provides tailored solutions that integrate complex machine vision and precise motion control for manufacturing processes. Their offerings enhance operational efficiency and improve quality control in demanding production environments.

The startup offers a manufacturing management platform that analyzes production processes in real-time, enabling operators to measure performance and identify inefficiencies. By providing actionable insights, the platform helps manufacturers reduce costs and enhance profitability across the production floor.

The startup manufactures relocatable cleanroom and laboratory units that provide controlled environments for sensitive processes. Their products, including mobile cleanrooms and integrated pods, enable clients to establish aseptic conditions for research, manufacturing, and data storage in a flexible manner.

CropBiome specializes in sourcing and fermenting specific microbes to produce biological products that enhance soil health and crop resilience. The company provides sustainable agricultural solutions that improve crop yield while reducing dependence on chemical fertilizers.

The startup has developed a patented synthetic antimicrobial topical gel that utilizes sustained release of reactive oxygen species (ROS) to effectively combat a wide range of bacterial and fungal pathogens, including those with resistance profiles. This technology provides a solution for infections, nasal decontamination, and medical device coatings, validated by leading research institutes.

The startup operates a data gathering and visualization platform that utilizes wireless sensor technology, digital workflows, and pick-to-light systems to analyze key performance indicators in manufacturing. This platform enables companies to identify inefficiencies and implement corrective actions, fostering ownership and collaboration while minimizing operational losses.

The startup develops plant-derived compound medicines that target DNA breakage by utilizing five isolated compounds to activate repair pathways. This approach prevents the emergence of drug-resistant strains and eliminates potential escape routes for cancer cells.

Nernst builds ultra‑efficient, low‑cost oxygen generators that extract high‑purity oxygen directly from air using ceramic Oxygen Generation technology and additive‑manufactured components. Their on‑site units replace energy‑intensive, capital‑heavy methods, offering continuous, reliable oxygen supply for industrial applications while reducing both operating costs and carbon footprint.

The startup operates an additive manufacturing platform that enables on-demand design and production of 3D-printed components. By offering services that encompass the design, printing, and management of these parts, the platform helps manufacturers reduce lead times and minimize supply chain risks while lowering their carbon footprint.