Top 50 Chemical Manufacturing in Canada

Anodyne utilizes enzymatic processes to convert CO2 into carbon negative chemicals, addressing the high greenhouse gas emissions and energy consumption of the traditional chemicals industry. Their technology operates at room temperature with zero emissions and low utility costs, providing safe and efficient production of essential low carbon products.

Brilliant Matters develops and manufactures organic semiconductors using proprietary chemical processes for printed electronics applications, including organic solar cells and photodetectors. The company addresses the need for a reliable supply of high-quality materials that support the commercialization of sustainable energy technologies.

Good Chemistry Company utilizes computational modeling and simulation techniques to design healthier and more sustainable materials, addressing the inefficiencies in material development faced by industries under environmental constraints. Their technology enables faster material innovation, contributing to solutions for challenges such as toxic chemical elimination and enhanced energy storage.

The startup offers a cloud-based manufacturing system that automates manual tasks, including compliance record keeping, inventory tracking, and cultivar-specific workflow management. This technology enhances operational efficiency and enables rapid preparation of audit packages, ensuring companies maintain Good Manufacturing Practice (GMP) compliance.

Basetwo provides an AI co-pilot for manufacturing that generates real-time recommendations to optimize yield, cycle time, and costs by leveraging machine learning and data integration. The platform addresses inefficiencies in highly regulated engineering environments, enabling engineers to reduce energy and material consumption by 20-30% and streamline cycle times by up to 40%.

Viridis develops electro-oxidation technology to eliminate organic pollutants from water sources, specifically targeting toxic dyes and microplastics in textile wastewater. This approach addresses the critical issue of water pollution, ensuring access to clean and usable water for households, industries, and municipalities.

Aplantex extracts and purifies plant-based active compounds for use in pharmaceuticals, cosmetics, and agri-food applications. The company provides sustainable alternatives to synthetic ingredients, meeting the growing demand for eco-friendly solutions in these industries.

Glassdome provides a platform that integrates real-time data from manufacturing equipment to enhance operational efficiency and reduce carbon emissions. By delivering actionable insights and automated reporting, the solution enables manufacturers to optimize production processes and comply with sustainability regulations.

pH7 Technologies utilizes a proprietary clean technology process to extract critical metals, such as platinum and copper, from recycled materials and low-grade ores with zero carbon emissions. This approach enhances resource recovery by up to 50% while significantly reducing energy consumption by up to 90%, addressing the growing demand for sustainable metal supply in the green energy transition.

Hydrogen Optimized manufactures RuggedCell™ high-power water electrolyzers that convert renewable electricity into clean hydrogen at scale, addressing the need for low-cost hydrogen production in industrial applications. Their technology enables efficient operation with minimal maintenance, ensuring high uptime and adaptability to variable power inputs from sources like solar and wind.

BryoSphere Biotechnologies utilizes genetic engineering of moss plants to synthesize rare, plant-derived specialty compounds with higher yields than their natural sources. The company focuses on developing treatments for skin hyperpigmentation and anti-cancer drugs, addressing the limited availability of these valuable compounds in traditional markets.

Carbon Upcycling utilizes a patented technology platform to transform local industrial byproducts and natural materials into carbon-sequestering cement replacements, effectively reducing the carbon footprint of concrete production. This process addresses the significant CO2 emissions generated by the cement industry, which accounts for eight percent of global emissions, while enhancing concrete performance and durability.

Laserax designs and manufactures high-power laser systems for industrial applications, including laser cleaning and laser marking. Their solutions enable efficient surface preparation, contaminant removal, and permanent part identification for various manufacturing processes.

Polystyvert utilizes a dissolution recycling process to convert various types of post-consumer polystyrene into high-quality recycled pellets suitable for re-extrusion and re-injection. This technology addresses the significant issue of polystyrene waste, which is often contaminated and not recycled, by enabling a circular economy that reduces landfill contributions and reliance on virgin plastic production.

Oden Technologies provides AI-driven Process AI software that delivers real-time prescriptive recommendations to manufacturing operators, enabling them to optimize production processes immediately. This technology addresses the challenge of inexperienced operators by equipping them with actionable insights, resulting in significant increases in production efficiency and reduced downtime.

Neptune Nanotechnologies develops a proprietary process to extract chitin nanocrystals from organic ocean waste, creating high-performance, biodegradable materials. This technology enhances the strength and biocompatibility of products across various industries, including aerospace, biomedical, and packaging, while promoting environmental sustainability.

OmniaBio is a contract development and manufacturing organization specializing in the production of gene-modified cell therapies and lentiviral vectors, facilitating the transition from preclinical development to commercial-scale manufacturing. The company addresses the need for efficient and reliable manufacturing processes in the cell and gene therapy sector, ensuring that life-changing therapeutics reach patients effectively.

Produces green hydrogen using renewable energy sources, deploying a network of production facilities and distribution technologies across North America. This approach addresses the need for sustainable hydrogen solutions to support decarbonization efforts and reduce reliance on fossil fuels.

Loop Industries utilizes proprietary technology to convert waste PET plastic and polyester fiber, which are not conventionally recyclable, into high-purity, virgin-quality PET resin. This process addresses the issue of single-use plastics by enabling a circular economy through the production of 100% recycled content materials.

No Meat Factory specializes in co-manufacturing 100% plant-based protein alternatives using high moisture extrusion and clean label production methods. The company addresses the demand for tasty, nutritious, and affordable meat substitutes, catering to the growing market for plant-based food products.

Electra Battery Materials produces battery-grade cobalt sulfate and other materials through refining and recycling processes to support North America's electric vehicle and energy storage industries. By establishing a domestic supply chain, Electra addresses the reliance on overseas sources, enhancing sustainability and reducing geopolitical risks in battery material procurement.

Aurora Hydrogen utilizes microwave energy to heat methane in an oxygen-free environment, enabling the production of low-carbon hydrogen and solid carbon through water pyrolysis without direct CO2 emissions. This technology offers a scalable solution for industrial hydrogen demands, significantly reducing operating costs by using 80% less electricity compared to traditional methods.

CarbiCrete utilizes a manufacturing process that replaces cement with steel slag and incorporates captured CO2 to produce cement-free concrete, significantly reducing greenhouse gas emissions. This technology addresses the high carbon footprint of traditional concrete production by embedding up to 300,000 kg of CO2 in concrete masonry units annually, while also repurposing industrial waste.

Membio is developing a fully automated, single-use bioreactor system designed for cell and gene therapy manufacturing, providing a consistent environment for cell growth across scales from 0.2 to 10 liters. This platform addresses the challenges of cost-effective and scalable production, enabling manufacturers to achieve reliable results without the need for multiple processes.

This startup develops an integrated, end-to-end continuous manufacturing process for pharmaceuticals, transforming raw materials into final drug products. Their technology aims to reduce production costs and increase efficiency for pharmaceutical companies.

Mangrove Lithium utilizes its patented Clear-Li™ technology to convert lithium chloride and lithium sulfate from various feedstocks into high-purity lithium hydroxide and carbonate, minimizing waste and chemical use. This approach addresses the inefficiencies and high costs associated with traditional lithium refining methods, enabling scalable and cost-effective production near extraction sites or recycling operations.

Dispersa produces the world's first waste-derived biosurfactants by utilizing food waste as a raw material, eliminating the need for palm and petroleum sources. This approach not only provides a biodegradable and eco-friendly alternative for cleaning and personal care products but also offers a cost-effective solution in the biosurfactant market.

The startup produces plant-based renewable materials using probiotic-based natural odor control technology, aimed at replacing petrochemicals and reducing carbon emissions in consumer products. This approach enables brands to transition to sustainable materials that enhance product performance while minimizing environmental impact.

CarboNet's NanoNet platform utilizes programmable flocculants and coagulants to enhance water treatment efficiency across various industries, significantly reducing chemical costs and operational expenses. The technology addresses freshwater scarcity and regulatory challenges by enabling companies to cut treatment costs by up to 50% and minimize toxic chemical usage by 90%.

FLITE utilizes laser surface functionalization and open-air diamond-like coatings to enhance the durability and performance of materials across various industries, including aviation, oil and gas, and automotive. Their technology effectively reduces corrosion, friction, and maintenance costs while minimizing the need for toxic chemical coatings.

Anomera utilizes a patented manufacturing process to produce sustainable cellulose materials sourced from FSC®-certified forests, offering biodegradable alternatives to petroleum-based plastics and microplastics. Their products enhance performance in various applications, including cosmetics, bioplastics, and coatings, while reducing volatile organic compounds and CO2 emissions in industrial processes.

This startup specializes in a nanotechnology manufacturing process that produces various nanomaterials in large quantities with minimal waste. By optimizing resource utilization, the company enables the chemical industry to meet specific additive requirements in all manufacturing processes.

The startup operates a bioluminescent light platform that harnesses biochemical reactions in engineered organisms to produce sustainable light. This technology aims to eliminate toxic chemical waste from traditional lighting methods, providing an eco-friendly alternative for commercial applications.

The startup develops biodegradable plastic materials from plant-based biomass, providing a sustainable alternative to petroleum-based ABS plastic. This technology directly addresses the issue of plastic pollution by offering a natural replacement that reduces reliance on fossil fuels.

The startup has developed a patented hydro-metallurgical process for copper extraction that operates without electricity, producing high-purity copper metal and powders. This technology offers a scalable, low-energy alternative to traditional methods, addressing the increasing demand for copper in the green transition.

Valence Labs utilizes AI-driven methodologies to design novel chemical compounds targeting complex biological systems, aiming to enhance drug discovery processes. By merging academic research with industrial resources, the company seeks to accelerate the development of effective therapeutics for previously challenging medical conditions.

Elysis has developed a carbon-free aluminum production technology that eliminates direct greenhouse gas emissions while generating oxygen as a byproduct. This process addresses the environmental impact of traditional aluminum smelting, significantly reducing the carbon footprint of aluminum manufacturing.

Innova is developing a technology that produces low-cost clean graphite and hydrogen through electrochemical processes, targeting the decarbonization of hard-to-abate industries. This approach addresses the high emissions associated with traditional graphite and hydrogen production methods, offering a sustainable alternative for industrial applications.

Factry provides a unified platform for manufacturing operations to centralize and contextualize industrial data. It enables real-time visibility into production performance, allowing teams to identify bottlenecks and optimize processes for improved efficiency.

Galaxy Genomics offers a deterministic molecular engineering platform that uses proprietary quantum-grade computational algorithms to precisely analyze, design, and optimize molecular systems. This accelerates innovation and reduces development timelines for clients in pharmaceuticals, life sciences, and various industrial sectors.

BioOilSolv utilizes catalytic pyrolysis technology to convert forestry, agricultural, and municipal waste into biomass-derived solvents for bitumen recovery. This process significantly reduces the carbon footprint of chemical production by at least 60%, replacing fossil fuels with sustainable alternatives.

Lite-1 develops microbial dyes using regenerative processes that utilize abundant microorganisms, eliminating the need for toxic chemicals and non-renewable resources. This approach provides a sustainable alternative for the fashion and textile industries, addressing environmental concerns associated with traditional dyeing methods.

Nanode designs and produces high-performance metal alloy anodes for lithium and sodium-ion batteries using a one-step melt spinning process, which eliminates the need for traditional slurry preparation. This technology provides greater energy storage capacity and reduces manufacturing time, addressing the limitations of conventional graphite anodes in electric vehicles and renewable energy applications.

The startup utilizes its Rapid Alloy Design (RAD)™ platform, which combines AI and Multi-Scale Simulations to design and optimize new alloys 100 times faster than traditional methods. This technology addresses the high costs and lengthy timelines associated with materials engineering by delivering bespoke alloys tailored to specific performance requirements in various industries.

The startup manufactures an automated polymer materials testing machine that conducts rapid stress tests on plastics and rubber using intelligent software for sample processing and data analysis. This technology enables materials manufacturers to reduce costs and time in product development by automating physical testing and data collection.

The startup operates a gas-to-liquids plant that converts natural gas and its derivatives into synthetic diesel and naphtha using a proprietary catalytic process. This technology provides low-carbon liquid fuels for transportation sectors, addressing the need for cleaner alternatives to traditional fossil fuels.

Ecocyclic upcycles mixed plastic waste into high-quality pyrolysis oil using an advanced chemical recycling process. This process enables the production of new, circular plastics, diverting waste from landfills and oceans while significantly offsetting CO2 emissions.

The startup produces potassium sulfate (SOP), potassium and magnesium sulfate (SOPM), and hydrochloric acid (HCl) as a by-product using a patented process that extracts potassium chloride, sulfuric acid, and magnesium compounds from mine tailings. This method provides farmers with tailored fertilizers that enhance crop yield while utilizing abundant raw materials, addressing the need for sustainable agricultural inputs.

VVector Bio offers biomanufacturing services that employ cell culture and fermentation techniques to produce complex biologics for novel therapeutics. The company provides scalable production solutions that comply with regulatory standards, significantly shortening the development timeline for new medicines.

This startup manufactures linear actuators and piston pumps utilizing shape memory alloys to provide precise motion control in automation applications. Their products enable efficient process automation and valve actuation by responding to temperature changes, enhancing operational reliability in industrial settings.