Vizgen develops the MERSCOPE UltraTM platform, which utilizes MERFISH technology for high-resolution, in situ single-cell spatial genomics analysis. This system automates sample imaging and cell segmentation, enabling researchers to obtain detailed spatial data on gene expression across whole tissue sections, thereby enhancing biological insights in their studies.
Funding
$136.2M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Spatial genomics analysis often requires complex workflows and compromises between resolution, throughput, and sensitivity, limiting researchers' ability to gain comprehensive insights from tissue samples. Existing methods may lack the ability to simultaneously analyze a large number of genes with subcellular resolution across whole tissue sections.
Solution
Vizgen's MERSCOPE UltraTM platform leverages MERFISH (Multiplexed Error-Robust Fluorescence In Situ Hybridization) technology to provide high-resolution, in situ single-cell spatial genomics analysis. The integrated system automates sample imaging, image analysis, and cell segmentation, enabling researchers to spatially profile and analyze the transcriptome of whole tissue sections with subcellular resolution. MERSCOPE UltraTM offers customizable gene panels up to 1000 genes, providing flexibility for different species and tissue types. The platform's class-leading cell segmentation, combined with high-quality spatial data, facilitates biological insights in the context of specific research goals.
Target Audience
The primary audience includes researchers in spatial biology, genomics, and related fields who seek to gain deeper insights into tissue organization, gene expression patterns, and cellular interactions.
Features
- End-to-end system integrating sample imaging, image analysis, and cell segmentation
- High-resolution, high-throughput imaging without compromising sensitivity
- Customizable gene panels up to 1000 genes for diverse research applications
- MERFISH technology for accurate and robust spatial genomics analysis
- Class-leading cell segmentation methods for precise single-cell output
- VPT (Vizgen Processing Tool) for cell boundary delineation and single-cell data generation