VivoSphere develops 3D cell culture models using tissue engineering technologies to create more physiologically relevant environments for in vitro drug discovery and toxicity testing. Their models replicate the tumor microenvironment with precise control over extracellular matrix components, enhancing the translatability of drug response results.
Funding
$31.8K raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional in vitro drug discovery and toxicity testing often lack physiologically relevant environments, leading to poor prediction of drug responses in humans. Existing 2D cell cultures fail to replicate the complex 3D tumor microenvironment and cell-matrix interactions crucial for accurate drug screening.
Solution
VivoSphere provides tissue-engineered 3D cell culture models that mimic human tissues for improved in vitro drug discovery and toxicity testing. These models replicate the 3D tumor microenvironment with precise control over extracellular matrix components and mechanical properties, enhancing the translatability of drug response results. VivoSphere's models support a wide range of cell types, including non-aggregating cells, and encapsulate a high number of cells for better assay readout. The assay-ready 3D tissues are compatible with lab automation systems and high-throughput screening.
Target Audience
VivoSphere's primary customers are pharmaceutical companies, biotech firms, and research institutions involved in drug discovery, toxicity testing, and oncology research.
Features
- High inter- and intra-batch uniformity for consistent results
- Tunable tissue microenvironment with hydrogel for customized models
- Compatibility with a wide range of cell types, including non-aggregating cells
- High cell encapsulation for improved assay readout
- Assay-ready format for high-throughput screening and lab automation
- Models replicate the 3D tumor microenvironment
- Control over extracellular matrix components and mechanical properties