The startup provides plasmid sequencing services using nanopore technology to ensure high-quality results with rapid turnaround times. Their offerings include validating plasmid insert orientation and backbone integrity, which helps researchers in academia and the pharmaceutical industry avoid contamination and primer issues.
Funding
$760K raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional plasmid sequencing methods like Sanger sequencing or short-read NGS can be time-consuming, expensive for large regions of interest, and may encounter difficulties with complex or repetitive sequences. Researchers also face challenges in ensuring the accuracy of plasmid insert orientation and detecting genomic DNA contamination.
Solution
Unveil Bio offers whole plasmid and amplicon sequencing services leveraging nanopore technology to provide comprehensive and high-quality results with a rapid turnaround time of three days. The service eliminates the need for primer design and annealing, validating the entire plasmid sequence, including insert orientation, origin of replication, and marker functionality. Unveil Bio's proprietary bioinformatics pipeline generates fully annotated plasmid assemblies and quality reports, enabling researchers to identify low-quality positions, potential variants, and genomic DNA contamination. The company's streamlined process requires minimal DNA sample input and provides PhD-level customer support to assist with project design, data interpretation, and troubleshooting.
Target Audience
Unveil Bio serves researchers in academia, the pharmaceutical industry, healthcare, and biotechnology who require accurate and rapid plasmid sequencing for applications such as validating insert orientation, confirming plasmid integrity, and detecting genomic DNA contamination.
Features
- Whole plasmid sequencing for plasmids between 2.5-25 kb and amplicon sequencing for fragments between 0.7-10 kb
- Nanopore sequencing technology with >99% raw read accuracy and >99.999% consensus accuracy
- PCR-free library preparation method to avoid amplification bias
- Comprehensive analysis package including annotated GenBank file, quality PDF, read length plot, and quality TSV file
- gDNA contamination score to quantify the proportion of genomic DNA in the sample
- Automated sample processing using robotics and a proprietary bioinformatics pipeline
- User-friendly online platform for order registration, sample tracking, and data download
- Option to submit samples via mail or designated dropboxes