This startup offers a spatial omics platform designed for oncology research, providing comprehensive analysis of tissue samples. Their platform enables researchers to gain insights into the spatial organization of cells and molecules within tumors, accelerating translational research in cancer.
Funding
Funding not disclosed
Founders
Product
Problem
Current methods for analyzing tumor tissue samples often lack the ability to comprehensively capture the spatial context of cells and molecules, hindering the discovery of new biomarkers and therapeutic targets. This limitation makes it difficult to fully understand tumor-immune interactions and predict treatment response.
Solution
The Translational Spatial Profiling Center (TSPC) offers an end-to-end spatial omics platform that combines computational biology, quantitative biomedicine, and advanced imaging technologies to provide comprehensive spatial profiling of cancer patient cohorts. The platform utilizes highly multiplexed imaging of patient tissue biospecimens, followed by a standardized image analysis pipeline. The extracted spatial features are then used to improve patient stratification and predict therapeutic response in neoplastic diseases.
Target Audience
The primary audience includes clinical researchers and collaborators interested in improving patient stratification, diagnosis, and treatment of neoplastic diseases, particularly those with clinically defined cancer patient cohorts and relevant biomaterial and clinical metadata.
Features
- Highly multiplexed imaging using the Lunaphore COMET® system
- Standardized image analysis pipeline for processing image data
- Bioinformatics methods for analyzing the spatial distribution and interaction of cell types
- Multimodal analysis integrating various data types with clinically relevant data
- Focus on tumor-immune interactions
- Application to non-small cell lung cancer and intrahepatic cholangiocarcinoma