Torpedo Therapeutics
This company develops micro- and nano-fabricated electrode leads for high-precision deep brain stimulation (DBS) that offer single-neuron resolution targeting. They integrate these leads with a control chip and a machine learning platform for closed-loop sensing and automated parameter adjustment based on neural activity. This technology aims to reduce off-target side effects and eliminate the need for frequent, manual DBS reprogramming.
- Artificial Intelligence
- Biotechnology
- Hardware
- Healthcare Technology
Funding
Funding not disclosed
Founders
Product
Problem
Existing deep brain stimulation (DBS) therapies utilize large electrodes that lack spatial precision, leading to off-target stimulation and associated side effects. Continuous, open-loop stimulation protocols can also result in decreased responsiveness over time, necessitating frequent clinical reprogramming and increasing the burden on patients.
Solution
Torpedo Therapeutics is developing high-precision, closed-loop DBS devices that leverage micro- and nano-fabrication technologies to create ultra-small electrodes. These micro-electrodes enable stimulation with single-neuron precision, minimizing off-target effects and potential side effects. The system incorporates real-time neural activity sensing and a machine learning-driven data analysis platform to automatically adjust stimulation parameters, reducing the need for frequent reprogramming and optimizing long-term efficacy. This closed-loop approach aims to provide more personalized and adaptive therapy for neurological disorders.
Target Audience
The primary target audience includes patients with Parkinson’s disease, Essential Tremor, Dystonia, and drug-resistant Epilepsy, as well as clinicians specializing in deep brain stimulation therapies.
Features
- Micro-electrode leads with individual electrodes 150 times smaller than existing DBS electrodes
- High spatial resolution stimulation capable of single-neuron precision
- Closed-loop sensing and stimulation platform for real-time neural activity monitoring
- Machine learning-driven data analysis platform for predictive assessments
- Automated adjustment of stimulation parameters based on local neural activity
- Electronic chip for signal readout and stimulation control, designed to replace bulky implantable pulse generators