The startup operates a programmable RNA vaccine platform that enhances design, delivery, and bio-manufacturing processes for vaccines and immunotherapies. This technology enables the rapid development of effective nucleic acid products, providing safer and more affordable treatment options for human and animal diseases.
Funding
$7.4M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current RNA medicines often rely on lipid nanoparticles (LNPs) for delivery, which can lead to dose-limiting toxicities, inflammation, and intellectual property licensing constraints. This limits the potential of RNA-based vaccines and therapeutics.
Solution
Tiba Biotech is developing a novel RNA medicine platform based on fully biodegradable nanoparticles and advanced RNA design for safer and more effective vaccines and therapeutics. Their approach overcomes the limitations of traditional LNPs by using rationally designed, fully synthetic, high molecular weight molecules for RNA compaction and delivery, reducing the need for large quantities of excipient carrier materials. The platform enables delivery of more complex RNA structures that express desired protein content at well-defined ratios. Tiba Biotech's technology aims to maximize the effective dose of RNA administered to the patient while reducing side effects.
Target Audience
The primary target audience includes pharmaceutical companies and research institutions focused on developing advanced vaccines and therapeutics for human and animal health.
Features
- Fully biodegradable nanoparticles for RNA delivery, offering improved safety profiles compared to LNPs
- Rational design approach to maximize the effective RNA dose and reduce side effects
- Payload capacity greater than traditional LNPs, enabling more complex RNA structures
- Algorithms and a database of annotated nucleic acid structures for rapid development of candidate applications
- Customizable delivery chemistries to meet different RNA product profiles
- Broad range of applications, including vaccines, immuno-oncology, gene delivery, and gene editing