Ten Bio specializes in ex vivo skin culture techniques that provide a reliable platform for evaluating dermatological treatments and products in laboratory settings. This method offers an ethical alternative to animal testing, ensuring accurate results while adhering to regulatory standards in the biotechnology sector.
Funding
$1.3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional methods of evaluating dermatological treatments and products often rely on animal testing, which raises ethical concerns and may not accurately predict human skin responses. Existing ex vivo models may lack the biological complexity and extended viability needed for comprehensive skin research.
Solution
Ten Bio provides TenSkin™, a patented ex vivo human skin model that offers a biologically relevant platform for evaluating dermatological treatments and products. TenSkin™ utilizes full-thickness human skin, complete with dermal and epidermal layers, appendages, and minor skin cell populations, cultured under optimal mechanical tension to mimic in vivo conditions. This approach maintains skin integrity and viability for over two weeks, enabling researchers to investigate complex skin responses, assess compound efficacy, and predict clinical outcomes more accurately than traditional methods. Ten Bio also offers specialist research services, including experimental design, execution, and access to a catalog of standard operating procedures (SOPs) to accelerate R&D programs.
Target Audience
Ten Bio serves clients in medical aesthetics, cosmetics, drug development, and medical device testing, including research teams needing human-relevant testing for preclinical studies.
Features
- Full-thickness human skin model with intact stratum corneum, dermal and epidermal layers, and skin appendages
- Proprietary culture system maintains physiological mechanical tension, mimicking the in vivo environment
- Extended viability of 2+ weeks for studying long-term skin responses
- Suitable for various applications, including wound healing, injection studies, skin rejuvenation, and photobiology
- Customizable assays and disease models available
- Histological workup, brightfield and confocal microscopy, RNA isolation, and RT-qPCR analysis
- Ethically sourced and fully consented surplus surgical tissue