Stimdia Medical has developed the pdSTIM™ System, a neurostimulation therapy that uses percutaneously inserted leads to stimulate the phrenic nerves and recondition the diaphragm for independent breathing. This technology addresses ventilator-induced diaphragmatic dysfunction in mechanically ventilated adults, facilitating faster weaning from mechanical ventilation after prolonged use.
Funding
$30M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
SBFounders
Product
Problem
Prolonged mechanical ventilation can lead to ventilator-induced diaphragmatic dysfunction (VIDD), characterized by muscle atrophy and weakness, which significantly hinders weaning efforts and extends a patient's reliance on respiratory support. This prolonged ventilation increases healthcare costs and contributes to higher morbidity and mortality rates.
Solution
Stimdia Medical's pdSTIM™ System is a neurostimulation therapy designed to address VIDD and facilitate faster weaning from mechanical ventilation. The system employs percutaneously inserted leads to stimulate the phrenic nerves, thereby reconditioning the diaphragm and restoring its ability to support independent breathing. By recognizing the onset of inspiration and delivering targeted stimulation, the pdSTIM™ System helps to reverse the effects of VIDD and accelerate the transition to spontaneous respiration. The minimally invasive approach allows for bedside placement in the ICU without interfering with existing lines or ventilator settings.
Target Audience
The primary target audience includes mechanically ventilated adults, at least 18 years old, suffering from diaphragmatic dysfunction who have been on mechanical ventilation for ≥ 96 hours and have failed at least one weaning attempt.
Features
- Percutaneously inserted temporary pacing leads for phrenic nerve stimulation.
- Bedside placement in the ICU setting.
- Designed to integrate with existing lines and leads.
- Compatible with various ventilator types and modes of operation.
- Minimally invasive placement of small 3 Fr leads through an 18-gauge needle introducer.
- Intended to facilitate weaning via temporary stimulation of the phrenic nerve.