Sphere Fluidics develops picodroplet microfluidic technology for high-throughput single cell analysis and isolation, enabling the screening of millions of viable cells within hours. Their solutions enhance efficiency in biologics discovery and development by providing precise, reliable data for cell engineering and synthetic biology applications.
Funding
Funding not disclosed
Founders
Product
Problem
Traditional cell analysis and isolation methods are often time-consuming, labor-intensive, and lack the precision needed for efficient biologics discovery, cell engineering, and synthetic biology applications. Screening large cell populations for specific traits or antibodies can be particularly challenging, hindering the development of new biotherapeutics and engineered cell lines.
Solution
Sphere Fluidics offers picodroplet microfluidic technology that enables high-throughput single-cell analysis and isolation. Their platforms encapsulate individual cells within tiny droplets, creating miniaturized reaction vessels for conducting millions of assays in a matter of hours. This approach allows researchers to screen cells based on viability, productivity, or other desired characteristics with greater speed, accuracy, and monoclonality assurance. The technology facilitates the selection of rare cells with specific functions, accelerating workflows in antibody discovery, cell line development, cell engineering, and synthetic biology.
Target Audience
The primary target audience includes researchers and developers in biologics discovery, cell line development, cell engineering, synthetic biology, and cell therapy who require high-throughput, single-cell analysis and isolation tools.
Features
- Cyto-Mine® platform for automated single-cell analysis and isolation
- Cyto-Mine® Chroma enables multiplexed assays for in-depth cell characterization
- Picodroplet technology encapsulates single cells in miniaturized, stable, and biocompatible droplets
- Cyto-Cellect® assay kits for detecting IgG antibodies (Human, Mouse, and Fc Fusion) and assessing cell viability
- Consumables and reagents optimized for picodroplet microfluidics, including Cyto-Surf® surfactants and Pico-Surf®
- Enables screening of millions of viable cells in a single day
- Facilitates monoclonality assurance for cell line development