Sonnest, Inc. is developing Electrast™, an ultrasound imaging contrast agent that activates in the myocardium to provide real-time assessment of cardiac perfusion without ionizing radiation or toxic dyes. This technology enables rapid, cost-effective evaluation of heart function at the point of care, addressing the need for safer diagnostic methods in patients with coronary artery disease.
Funding
$4M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.

Founders
Product
Problem
Current methods for assessing cardiac perfusion often involve ionizing radiation or nephrotoxic contrast dyes, posing risks to patients, especially those with renal insufficiency or requiring repeated imaging. Traditional techniques may also lack the real-time resolution needed for timely evaluation of myocardial function at the point of care.
Solution
Sonnest is developing Electrast™, an electrically sensitive ultrasound contrast agent designed to provide real-time assessment of cardiac perfusion without the use of ionizing radiation or toxic dyes. Electrast™ activates in the presence of ultrasound and the heart's local electric field, indicating viable, perfused tissue. This technology aims to enable rapid and cost-effective evaluation of heart function, improving diagnostic safety and accessibility for patients with or at risk of coronary artery disease. The activated agent provides enhanced myocardial imaging, allowing for better data acquisition and faster diagnosis.
Target Audience
The primary target audience includes cardiologists, hospitals, and imaging centers seeking safer and more efficient methods for assessing cardiac perfusion in patients with or at risk of coronary artery disease.
Features
- Electrically sensitive contrast agent that activates with ultrasound in perfused cardiac tissue
- Real-time assessment of myocardial perfusion
- Enhanced ultrasound imaging without ionizing radiation or nephrotoxic dyes
- Point-of-care cardiac perfusion data acquisition