Singleron Biotechnologies provides end-to-end single cell multi-omics solutions, utilizing proprietary technologies for tissue preservation, dissociation, and automated bioinformatics analysis. Their offerings enable researchers to efficiently generate high-quality single cell sequencing data, addressing the challenges of time-consuming sample processing and complex data interpretation in precision medicine.
Funding
$100M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
FCLBFounders
Product
Problem
Researchers and clinicians often face fragmented, labor‑intensive workflows for single‑cell multi‑omics, requiring separate tissue dissociation, cell capture, library preparation, and data analysis tools. High equipment costs and complex protocols limit scalability and reproducibility, especially for large‑scale clinical or drug‑discovery projects.
Solution
Singleron Biotechnologies offers a complete, end‑to‑end single‑cell sequencing platform that integrates tissue preservation, automated dissociation, microfluidic cell partitioning, barcoding, library construction, and cloud‑based bioinformatics. Proprietary microfluidic SCOPE‑chip technology enables high‑throughput, low‑doublet capture of cells or nuclei from diverse sample types, including FFPE tissue. Automated instruments such as Matrix NEO and Tensor provide scalable processing from a few samples up to thousands per run, reducing hands‑on time and variability. Complementary reagent kits (e.g., RetroSCOPE® FFPE, GEXSCOPE, MobiuSCOPE) support transcriptome, full‑length, immune‑repertoire, and targeted variant profiling. Integrated software pipelines deliver code‑free analysis, database storage, and customizable reports, allowing users to translate deep molecular insights into actionable biomedical decisions.
Target Audience
Primary customers are academic and industry researchers, clinical laboratories, and pharmaceutical R&D teams that require scalable, high‑quality single‑cell multi‑omics data for disease studies, biomarker discovery, and therapeutic development.
Features
- Microfluidic microwell SCOPE‑chip with patented bead configuration for precise single‑cell or single‑nucleus capture and low doublet rates
- Automated tissue dissociation systems (PythoN i™ and PythoN Junior®) that preserve cell viability across a wide range of tissue types, including organoids and FFPE samples
- High‑throughput instruments (Matrix NEO, Tensor) capable of processing 1–4 samples simultaneously or scaling to thousands of cells per run
- Comprehensive reagent kits covering standard scRNA‑seq, full‑length RNA, TCR/BCR profiling, targeted variant capture, microbial RNA, and time‑resolved sequencing
- End‑to‑end cloud bioinformatics suite (Celescope, Synecosys, Celelens) offering code‑free data processing, single‑cell database integration, and customizable visual reports
- Sample multiplexing (CLindex) and barcode strategies to maximize data output and reduce per‑sample costs
- Compatibility with downstream applications such as oncology, immunology, neuroscience, and plant research, and integration with existing laboratory workflows