The startup provides biotechnology research and development services focused on the genomic editing of fertilized eggs using the electroporation method, enabling high-throughput production of genetically modified mice. This technology supports clients in the creation and commercialization of genetically modified mouse models for research and therapeutic applications.
Funding
$6.9M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
SBFounders
Product
Problem
Generating genetically modified mice for research and therapeutic applications is often limited by traditional methods that are inefficient and can damage fertilized eggs. This can result in low-throughput production and increased costs for researchers requiring specific genetically modified mouse models.
Solution
Setsurotech provides biotechnology research and development services specializing in high-throughput production of genetically modified mice through genomic editing of fertilized eggs. The company utilizes the proprietary GEEP (Genome Editing by Electroporation) method, which introduces CRISPR/Cas9 genome editing tools into fertilized eggs via electroporation. This technique enables high-efficiency, low-cost, and low-damage modification, simplifying the creation of genetically modified mice. Setsurotech also offers the VIKING method for cultured cell genome editing, which minimizes off-target effects and uses three vectors for complex genome editing tasks.
Target Audience
Setsurotech serves researchers and organizations in the biotechnology, pharmaceutical, and agricultural sectors who require custom genetically modified mice and cells for research, drug discovery, and product development.
Features
- GEEP (Genome Editing by Electroporation) for efficient and low-damage genome editing in fertilized eggs
- VIKING method for cultured cell genome editing, reducing off-target effects
- ST9.5, a proprietary and improved nuclease for CRISPR/Cas systems
- Custom knockout and knock-in mouse creation services
- Production of floxed mice using the 1-step flox service
- BRJ mice, a highly immunodeficient mouse optimized for human tumor cell transplantation
- Monoclonal antibody production services using DNA immunization