This company develops clinically validated, drug and hormone-free neurotechnology solutions for menstrual health issues. They offer neurostimulation devices and a CycleSync software application for symptom prediction and cycle management. The core value is providing non-invasive relief for period pain and mood symptoms by balancing brain activity across the menstrual cycle.
Funding
$5.1M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.





Founders
Product
Problem
Many women experience debilitating menstrual pain and mood fluctuations associated with their menstrual cycles, often relying on over-the-counter painkillers or hormonal birth control for relief, which may have limited effectiveness or undesirable side effects. Current treatments often overlook the neurological component of these symptoms.
Solution
Samphire Neuroscience offers Nettle, a wearable neurotechnology device that non-invasively stimulates brain regions responsible for emotional regulation and pain perception, providing a drug-free alternative for managing menstrual-cycle-related symptoms. The Nettle headband delivers low electrical current, a type of brain stimulation called transcranial direct current stimulation (tDCS), to target the motor cortex (for pain perception) and the prefrontal cortex (for mood regulation). By increasing neuroplasticity, the device aims to reduce sensitivity and block pain signals, addressing both the physical and psychological symptoms associated with menstruation. The wearable is designed for use in the days leading up to a period, offering a proactive approach to symptom management.
Target Audience
The primary target audience includes women experiencing menstrual pain and/or PMS, seeking a drug-free, non-invasive alternative to manage their symptoms.
Features
- Non-invasive brain stimulation via a head-mounted wearable device
- Transcranial direct current stimulation (tDCS) technology
- Targets the motor cortex to reduce pain perception
- Targets the prefrontal cortex to improve mood regulation
- Battery-operated with a single-button activation for ease of use
- Conductive sponges ensure proper current flow during 20-minute sessions
- Designed to accommodate various head sizes and shapes
- Mobile app for treatment reminders and period tracking