RevBio has developed TETRANITE®, a synthetic bone adhesive bioengineered from marine-derived proteins, designed for effective bone-to-bone and bone-to-metal applications. This technology addresses the longstanding challenge of creating a biocompatible adhesive that provides rapid mechanical stability and controlled biodegradability, significantly improving surgical outcomes in orthopedic and dental procedures.
Funding
$2.4M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current bone adhesives often lack biocompatibility, fail to provide rapid mechanical stability in wet environments, and do not fully integrate with the surrounding bone tissue, leading to compromised surgical outcomes and prolonged healing times. Existing solutions may also require multiple surgical events and ancillary fixation devices.
Solution
RevBio's TETRANITE® is a synthetic bone adhesive bioengineered from marine-derived proteins, designed for effective bone-to-bone and bone-to-metal adhesion in wet field conditions. TETRANITE® transforms from a pliable putty to a cement-like scaffold upon mixing with an aqueous medium, providing rapid mechanical stability. The adhesive is osteoconductive and bioactive, facilitating the replacement of the TETRANITE® scaffold with new bone over time, transferring load-bearing responsibility to the new tissue while maintaining mechanical integrity. As a synthetic product, TETRANITE® can be produced in large quantities at a low cost.
Target Audience
The primary target audience includes orthopedic and dental surgeons seeking improved bone adhesives for fixation, fusion, and grafting procedures, as well as veterinary surgeons.
Features
- Bioengineered from marine-derived proteins for enhanced biocompatibility
- Wet field performance, enabling effective bonding in surgical environments
- Multi-surface bonding capabilities for bone-to-bone and bone-to-metal applications
- Rapid mechanical stability, providing immediate fixation
- Controlled biodegradability, allowing for gradual replacement with new bone tissue
- Osteoconductive and bioactive properties to promote bone regeneration
- Can withstand tensile and shear bond stresses as high as 3 MPa, similar to the strength of human cancellous bone