Reservoir Neuroscience is developing therapeutics aimed at repairing the blood-brain barrier, a critical structure that regulates the passage of substances between the bloodstream and the brain. This approach addresses the challenges of neurological diseases by restoring barrier integrity, potentially improving treatment outcomes for conditions like Alzheimer's and multiple sclerosis.
Funding
$6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
KTFounders
Product
Problem
The blood-brain barrier (BBB) regulates the passage of substances between the bloodstream and the brain, and its dysfunction is implicated in various neurological disorders. Current treatments for neurological diseases often face challenges due to a compromised BBB, which hinders drug delivery and exacerbates disease progression. This limitation underscores the need for therapeutic strategies that can restore BBB integrity.
Solution
Reservoir Neuroscience is developing therapeutics designed to repair and restore the blood-brain barrier. By focusing on BBB integrity, their approach aims to improve treatment outcomes for neurological conditions such as Alzheimer's disease and multiple sclerosis. These therapeutics are intended to enhance drug delivery to the brain, reduce inflammation, and promote overall neurological health by addressing the underlying dysfunction of the BBB.
Target Audience
The primary target audience includes individuals suffering from neurological diseases associated with BBB dysfunction, as well as pharmaceutical companies seeking to improve the efficacy of CNS-directed therapeutics.
Features
- Therapeutics designed to selectively target and repair the blood-brain barrier.
- Modulation of BBB permeability to enhance drug delivery to the brain.
- Reduction of inflammation and immune cell infiltration across the BBB.
- Promotion of tight junction integrity within the BBB endothelium.