Provides mass photometry systems and consumables for label-free single-molecule imaging and mass measurement in solution, enabling accurate characterization of biomolecules such as viral vectors, antibodies, and membrane proteins. This technology eliminates the need for fluorescent labels, reducing sample preparation time and improving data reliability for applications in life sciences and biopharma.
Funding
$115.1M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
NVFounders
Product
Problem
Traditional methods for characterizing biomolecules often require labels or alter the native state of the molecule, potentially leading to inaccurate or incomplete characterization. These methods can also be time-consuming and require significant sample amounts.
Solution
Refeyn provides mass photometry solutions that enable label-free, single-molecule imaging and mass measurement in solution. This technology allows for accurate characterization of biomolecules, including viral vectors, antibodies, and membrane proteins, without the need for fluorescent labels or other modifications. Refeyn's instruments, such as the TwoMP, TwoMP Auto, SamuxMP, and KaritroMP, offer rapid and comprehensive analysis, providing insights into molecular mass, aggregation, interactions, and sample homogeneity. The technology simplifies sample preparation, captures true molecular behavior in a native environment, and accelerates workflows in life sciences and biopharma.
Target Audience
Refeyn's products are targeted towards scientists and researchers in life sciences and biopharma, particularly those involved in cell and gene therapy, antibody development, and structural biology.
Features
- Label-free mass measurement of single molecules in solution
- Instruments for biomolecular characterization, AAV vector analytics, and large viral vector analysis
- Compatible with various membrane mimetics, including detergents and nanodiscs
- Software for data acquisition, automated analysis, and GMP compliance
- Consumables and calibrants optimized for mass photometry measurements
- Automated versions available for high-throughput screening and titration assays
- Microfluidics add-on for characterizing low-affinity interactions