RebrAIn offers a CE‑marked and FDA‑cleared AI‑driven software service that automates the pre‑operative targeting workflow for deep brain stimulation in Parkinson’s disease and essential tremor. By uploading a T1‑weighted MRI, clinicians receive millimetric, MRI‑guided coordinates for the subthalamic nucleus or ventral intermediate nucleus, standardizing target selection while integrating seamlessly with existing surgical planning tools.
Funding
$4M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Neurosurgical planning for deep brain stimulation in Parkinson’s disease and essential tremor is labor-intensive, requires expert interpretation of MRI data, and can vary between surgeons, leading to longer preparation times and potential inconsistencies in target accuracy.
Solution
RebrAIn provides a supervised AI‑driven software service that automates the pre‑operative targeting workflow for deep brain stimulation. Clinicians upload a T1‑weighted MRI, and the platform generates millimetric, MRI‑guided coordinates for the subthalamic nucleus (STN) or ventral intermediate nucleus (VIM). The AI model, trained on extensive clinical data, standardizes target selection while preserving surgeon oversight. The solution is delivered as a CE‑marked and FDA‑cleared Software as a Medical Device (SaMD) that integrates with existing planning systems, reducing planning time and improving consistency across sites.
Target Audience
Primary customers are neurosurgeons and hospital teams performing deep brain stimulation for Parkinson’s disease and essential tremor, as well as specialized movement‑disorder centers seeking to streamline and standardize their surgical planning processes.
Features
- Supervised AI algorithm that predicts optimal STN or VIM targets with millimetric precision from a single T1 MRI
- CE‑marked and FDA 510(k) cleared SaMD (OptimMRI and OptimDBS) ensuring regulatory compliance
- Health‑data exchange platform that securely imports imaging data and exports target coordinates to any surgical workflow
- Seamless integration with existing neurosurgical planning tools, requiring no additional hardware
- Standardized reporting and documentation to support regulatory and clinical audit trails
- Scalable deployment across multiple centers, currently adopted in 55 sites worldwide with over 500 targeting operations performed