React4life Srl develops the MIVO Multi In Vitro Organ platform, a unique organ-on-a-chip technology that utilizes 3D humanized tissue models and independently controlled millifluidic environments to replicate human biology. This technology enables precise and reproducible testing of drug interactions and disease mechanisms, facilitating the development of personalized therapies and accelerating drug discovery.
Funding
$660K raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional in vitro cell culture models often fail to accurately replicate the complexity of human biology, leading to unreliable results in drug testing and disease mechanism studies. Static environments and the lack of organ-organ interplay limit the predictability of these models. Existing organ-on-a-chip technologies may not offer sufficient tissue size or independent control over fluidic conditions.
Solution
React4life's MIVO Multi In Vitro Organ platform addresses these limitations with a unique organ-on-a-chip technology that utilizes 3D humanized tissue models within independently controlled millifluidic environments. The platform enables researchers to create dynamic, reproducible in vitro models that more closely mimic human physiology. By controlling fluid flow and providing a relevant tissue size, the MIVO platform allows for more accurate testing of drug interactions, disease mechanisms, and personalized therapies. The system supports single-organ and multi-organ configurations, allowing researchers to study organ-organ interactions.
Target Audience
The primary target audience includes researchers in biotech, pharmaceutical, nutraceutical, dermocosmetics, and medical device companies, as well as academic institutions studying cancer, immunology, and other complex diseases.
Features
- 3D humanized tissue models for improved replication of in vivo conditions.
- Independently controlled millifluidic environments to simulate dynamic physiological conditions.
- Single-organ and multi-organ configurations to study individual organs or organ-organ interactions.
- MIVO Single Flow, Double Flow, and Barrier configurations for diverse research applications.
- Customizable circuit configurations with options for closed or open circuits.
- Compatibility with various cell types, membranes, matrices, and tissues.
- Optically transparent chambers compatible with commercial inserts for easy sampling.