R3 Vascular develops bioresorbable polymer scaffolds using a proprietary manufacturing process to treat peripheral artery disease. These scaffolds provide a temporary support structure that promotes vascular healing while gradually resorbing, addressing the need for effective and less invasive treatment options.
Funding
$105.6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Peripheral artery disease requires interventions to restore blood flow, but traditional metallic stents can cause long-term complications such as restenosis and thrombosis. Permanent implants may limit future treatment options and prevent natural vessel function.
Solution
R3 Vascular develops bioresorbable scaffolds for treating peripheral artery disease, utilizing a proprietary manufacturing process and a unique ultra-high molecular weight polylactic acid (PLLA) polymer. These scaffolds provide temporary support to the artery, promoting vascular healing while gradually resorbing into the tissue, leaving a more naturally functioning vessel. The polymer composition and scaffold design are engineered to ensure predictable hydrolysis and maintain structural integrity during the healing period. R3 Vascular's vertically integrated manufacturing operations allow for customization and rapid iteration to create scaffolds with specific characteristics for various clinical applications.
Target Audience
The primary target audience includes interventional cardiologists, vascular surgeons, and interventional radiologists treating patients with peripheral artery disease.
Features
- Scaffolds made from ultra-high molecular weight PLLA, a proven bioresorbable material
- Proprietary processing techniques result in thinner, stronger, and more flexible scaffolds
- Engineered balance of amorphous and crystalline domains for controlled bioresorption
- High radial strength and circumferential support to maintain vessel patency
- Exceptional scaffold flexibility allows for resistance to fracture and conformability to vessel variability
- Low-profile designs with thin strut thickness
- Positive remodeling observed in animal studies