Quanterix provides a digital immunoassay platform that uses Single Molecule Array (Simoa) technology to deliver ultra‑sensitive, single‑molecule detection of protein biomarkers with femtomolar sensitivity and minimal sample volume. The automated, cartridge‑based system integrates fluid handling, optical reading, and data analysis software, enabling high‑throughput, quantitative assays for research, drug development, and clinical diagnostics.
Funding
Funding not disclosed
ASFounders
Product
Problem
Accurate measurement of low-abundance protein biomarkers in research and clinical samples often requires large sample volumes, expensive equipment, and complex protocols, limiting throughput and accessibility for many laboratories.
Solution
Quanterix offers a digital immunoassay platform that converts traditional ELISA assays into ultra-sensitive, single-molecule detection formats. The system uses bead-based assays combined with a proprietary optical reader to count individual enzyme-labeled molecules, achieving femtomolar sensitivity with minimal sample input. Automated fluid handling and integrated data analysis software streamline assay setup, execution, and result interpretation, enabling high-throughput biomarker quantification. The platform supports a broad library of validated assay kits and provides a development kit for custom assay creation, allowing researchers to expand the technology to new targets. Results are exported in standard data formats and can be linked to laboratory information management systems for seamless workflow integration.
Target Audience
Primary customers are biomedical research laboratories, pharmaceutical development teams, and clinical diagnostics groups that need highly sensitive protein quantification for biomarker discovery, drug development, and patient monitoring.
Features
- Single-molecule array (Simoa) technology delivering >1000× sensitivity over conventional ELISA
- Low sample volume requirement (as little as 10 µL) for serum, plasma, CSF, and tissue lysates
- Fully automated cartridge-based assay workflow with on-board reagent mixing and incubation
- Integrated software for real-time assay monitoring, data quality control, and quantitative reporting
- Extensive catalog of FDA-cleared and research-use-only assay kits covering cytokines, neurodegeneration markers, cardiac proteins, and more
- Open development kit enabling custom antibody pairing and assay optimization for novel targets