QT Sense

About QT Sense

This startup develops quantum sensing tools that utilize diamond magnetometry and confocal microscopy to precisely measure oxidative stress in biological samples. Their technology enables biomedical researchers to better understand and treat diseases linked to oxidative stress.

<problem> Real-time monitoring of cellular responses to oxidative stress is challenging, as prolonged oxidative stress can damage cells, proteins, and DNA, accelerating aging and contributing to various health conditions. Traditional methods often require external markers or dyes, which can affect cell viability or introduce measurement biases. </problem> <solution> QT Sense offers the Quantum Nuova, a single-cell Nano-MRI platform designed for biomedical research, enabling precise investigation of oxidative stress. The Quantum Nuova utilizes diamond magnetometry, employing fluorescent nanodiamonds with nitrogen-vacancy (NV) centers that are sensitive to magnetic noise produced by free radicals. The technology converts magnetic noise to an optical signal, allowing for non-invasive measurements of free radical concentrations within living cells at nanomolar levels and sub-cellular resolution. The system is fully automated, streamlining investigations and allowing researchers to focus on data analysis rather than operational nuances. </solution> <features> - Diamond magnetometry using fluorescent nanodiamonds (FNDs) with NV centers for nanoscale MRI measurements - T1 relaxometry technique to measure the fluorescence intensity decay, which correlates to free radical concentration - Laser-scanning confocal microscope for high-resolution 3D imaging and localization of FNDs within the sample - Fully automated system with precision focusing and sophisticated data analysis - Advanced particle tracking system for dynamic samples, automatically refocusing on the subject - Selective filter sets and avalanche photon detectors to maximize signal-to-noise ratio - Capability to measure various sample types, including live cells, tissues, and aqueous solutions - Optional cell incubator for samples requiring specific environmental conditions </features> <target_audience> The primary audience includes biomedical researchers studying oxidative stress, drug efficacy, and cellular dynamics, as well as those in fields such as oncology, reproductive health, and drug resistance research. </target_audience>

What does QT Sense do?

This startup develops quantum sensing tools that utilize diamond magnetometry and confocal microscopy to precisely measure oxidative stress in biological samples. Their technology enables biomedical researchers to better understand and treat diseases linked to oxidative stress.

Where is QT Sense located?

QT Sense is based in Groningen, The Netherlands.

When was QT Sense founded?

QT Sense was founded in 2024.

How much funding has QT Sense raised?

QT Sense has raised 6300000.

Location
Groningen, The Netherlands
Founded
2024
Funding
6300000
Employees
8 employees
Major Investors
QDNL Participations

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QT Sense

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Executive Summary

This startup develops quantum sensing tools that utilize diamond magnetometry and confocal microscopy to precisely measure oxidative stress in biological samples. Their technology enables biomedical researchers to better understand and treat diseases linked to oxidative stress.

qtsense.com300+
cb
Crunchbase
Founded 2024Groningen, The Netherlands

Funding

$

Estimated Funding

$5M+

Major Investors

QDNL Participations

Team (5+)

No team information available.

Company Description

Problem

Real-time monitoring of cellular responses to oxidative stress is challenging, as prolonged oxidative stress can damage cells, proteins, and DNA, accelerating aging and contributing to various health conditions. Traditional methods often require external markers or dyes, which can affect cell viability or introduce measurement biases.

Solution

QT Sense offers the Quantum Nuova, a single-cell Nano-MRI platform designed for biomedical research, enabling precise investigation of oxidative stress. The Quantum Nuova utilizes diamond magnetometry, employing fluorescent nanodiamonds with nitrogen-vacancy (NV) centers that are sensitive to magnetic noise produced by free radicals. The technology converts magnetic noise to an optical signal, allowing for non-invasive measurements of free radical concentrations within living cells at nanomolar levels and sub-cellular resolution. The system is fully automated, streamlining investigations and allowing researchers to focus on data analysis rather than operational nuances.

Features

Diamond magnetometry using fluorescent nanodiamonds (FNDs) with NV centers for nanoscale MRI measurements

T1 relaxometry technique to measure the fluorescence intensity decay, which correlates to free radical concentration

Laser-scanning confocal microscope for high-resolution 3D imaging and localization of FNDs within the sample

Fully automated system with precision focusing and sophisticated data analysis

Advanced particle tracking system for dynamic samples, automatically refocusing on the subject

Selective filter sets and avalanche photon detectors to maximize signal-to-noise ratio

Capability to measure various sample types, including live cells, tissues, and aqueous solutions

Optional cell incubator for samples requiring specific environmental conditions

Target Audience

The primary audience includes biomedical researchers studying oxidative stress, drug efficacy, and cellular dynamics, as well as those in fields such as oncology, reproductive health, and drug resistance research.

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