This startup develops quantum sensing tools that utilize diamond magnetometry and confocal microscopy to precisely measure oxidative stress in biological samples. Their technology enables biomedical researchers to better understand and treat diseases linked to oxidative stress.
Funding
$6.3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Real-time monitoring of cellular responses to oxidative stress is challenging, as prolonged oxidative stress can damage cells, proteins, and DNA, accelerating aging and contributing to various health conditions. Traditional methods often require external markers or dyes, which can affect cell viability or introduce measurement biases.
Solution
QT Sense offers the Quantum Nuova, a single-cell Nano-MRI platform designed for biomedical research, enabling precise investigation of oxidative stress. The Quantum Nuova utilizes diamond magnetometry, employing fluorescent nanodiamonds with nitrogen-vacancy (NV) centers that are sensitive to magnetic noise produced by free radicals. The technology converts magnetic noise to an optical signal, allowing for non-invasive measurements of free radical concentrations within living cells at nanomolar levels and sub-cellular resolution. The system is fully automated, streamlining investigations and allowing researchers to focus on data analysis rather than operational nuances.
Target Audience
The primary audience includes biomedical researchers studying oxidative stress, drug efficacy, and cellular dynamics, as well as those in fields such as oncology, reproductive health, and drug resistance research.
Features
- Diamond magnetometry using fluorescent nanodiamonds (FNDs) with NV centers for nanoscale MRI measurements
- T1 relaxometry technique to measure the fluorescence intensity decay, which correlates to free radical concentration
- Laser-scanning confocal microscope for high-resolution 3D imaging and localization of FNDs within the sample
- Fully automated system with precision focusing and sophisticated data analysis
- Advanced particle tracking system for dynamic samples, automatically refocusing on the subject
- Selective filter sets and avalanche photon detectors to maximize signal-to-noise ratio
- Capability to measure various sample types, including live cells, tissues, and aqueous solutions
- Optional cell incubator for samples requiring specific environmental conditions