ProteomEdge
ProteomEdge provides heavy-labeled recombinant protein standards (qRePS™) pre-aliquoted in 96-well plates for absolute multiplex quantification of blood plasma proteins by mass spectrometry. The three-step workflow—add plasma, digest, and run LC-MS/MS—eliminates custom standard preparation and calibration curves. Panels are validated for applications including venous thromboembolism triage and liver disease biomarker research.
- Biotechnology
Funding
Funding not disclosed
Founders
Founder details are not available yet.
Product
Problem
Absolute quantification of blood plasma proteins by mass spectrometry typically requires custom-made standards, complex calibration curves, and labor-intensive sample preparation. This limits throughput, reproducibility, and accessibility for researchers needing precise multiplex protein measurements.
Solution
ProteomEdge provides heavy-labeled recombinant protein standards (qRePS™) pre-aliquoted in 96-well plates, designed for absolute multiplex quantification of blood plasma proteins. The standards co-digest with raw plasma samples, establishing equilibrium with endogenous proteins and enabling absolute quantification in just three steps—add, digest, and run LC-MS/MS. Each panel comes with a supplied Skyline library for peptide identification, simplifying data analysis. The workflow eliminates the need for custom standard preparation and extensive calibration, making high-quality quantitative proteomics accessible to a broader range of laboratories.
Target Audience
Primary customers are mass spectrometry researchers and clinical proteomics laboratories focused on targeted quantitative analysis of blood plasma proteins, including those working in biomarker discovery, translational research, and clinical diagnostics development.
Features
- Pre-aliquoted, vacuum-dried heavy-labeled recombinant protein standards in 96-well plate format
- Co-digestion with raw plasma samples for equilibrium-based absolute quantification
- Three-step workflow: add plasma, digest together, quantify by LC-MS/MS
- Supplied Skyline library for streamlined peptide identification and quantification
- Pre-calibrated panels designed specifically for blood plasma analysis
- Panels validated for applications including venous thromboembolism triage, complement biology, and liver disease biomarker research