ProQomics provides a high‑throughput proteoform quantitation platform that enables researchers to measure up to 2,000 proteoforms per minute using mass‑spectrometry‑based workflows. The technology replaces thousands of Western blots with a faster, simpler protocol, delivering precise protein modification data for drug discovery, clinical research, biologics manufacturing, and diagnostic applications. By delivering multiplexed biomarker analysis in a single run, ProQomics accelerates decision‑making and supports precision‑medicine initiatives.
Funding
Funding not disclosed
Founders
Product
Problem
Researchers and manufacturers lack a high‑throughput method to quantify proteoforms and post‑translational modifications, forcing reliance on labor‑intensive techniques such as Western blots and limiting the ability to assess protein variants at scale.
Solution
ProQomics provides a proteoform quantitation platform that leverages existing high‑resolution mass spectrometry (HRMS) systems equipped with the ProQFiler front‑end instrument. The system automates sample preparation and integrates with HRMS to deliver rapid, mass‑spectrometry‑based analysis of up to 2,000 proteoforms per minute. By converting HRMS into a high‑throughput quantitation engine, the platform replaces thousands of manual Western blots with a streamlined workflow, enabling precise measurement of protein modifications for drug discovery, biologics manufacturing, and clinical diagnostics. The multiplex capability allows simultaneous identification and quantification of multiple biomarkers in a single run, supporting faster decision‑making in research and precision‑medicine applications.
Target Audience
Primary customers are pharmaceutical and biotech companies engaged in drug discovery and biologics manufacturing, as well as academic and clinical laboratories that require high‑throughput proteoform analysis for research and diagnostic purposes.
Features
- ProQFiler front‑end module that retrofits any HRMS system, functioning like an HPLC to increase sample throughput
- High‑throughput capacity of up to 2,000 proteoforms quantified per minute
- Automated workflow that eliminates the need for manual Western blotting and reduces hands‑on time
- Multiplexed analysis enabling simultaneous quantification of multiple protein biomarkers in a single run
- Compatibility with standard proteomics reagents and protocols for seamless integration into existing labs