Principal Medical develops patented vascular devices that improve outcomes for dialysis, pulmonary embolism, and lower‑extremity bypass patients.
Funding
Funding not disclosed
Founders
Product
Problem
Patients undergoing dialysis, treatment for pulmonary embolism, or lower extremity bypass surgery often experience vascular complications such as high-output heart failure, graft stenosis, pulmonary embolism, catheter occlusion, and graft failure, leading to hospitalizations and reduced quality of life.
Solution
Principal Medical designs patented vascular devices that address these complications at the source. Their flow‑optimizing arteriovenous (AV) grafts limit excessive blood flow to prevent high-output heart failure and outflow stenosis in dialysis access. A removable, atraumatic inferior vena cava (IVC) filter provides rapid, cross‑flow filtration to reduce pulmonary embolism risk in intensive care settings. A catheter‑clearance tool quickly restores dialysis catheter patency by mechanically removing fibrin and clot occlusions, minimizing treatment interruptions. For peripheral arterial disease, a lower‑extremity bypass graft with a proximal venous anastomosis maintains constant flow and mitigates intimal hyperplasia, improving long‑term graft patency. Together, these devices aim to reduce procedural complications, hospital stays, and improve overall patient outcomes.
Target Audience
Primary customers are hospitals, dialysis centers, and vascular surgery programs that manage patients requiring dialysis access, pulmonary embolism prevention, or lower extremity bypass procedures.
Features
- Flow‑restricted AV graft engineered to deliver optimal dialysis access flow, reducing high-output heart failure and outflow stenosis
- Removable IVC filter with cross‑flow filtration design for atraumatic, rapid pulmonary embolism prophylaxis in ICU patients
- Patented catheter clearance device that clears fibrin and clot occlusions within minutes, preserving dialysis schedule and catheter longevity
- Lower‑extremity bypass graft constructed from ePTFE with a proximal venous anastomosis to enhance runoff and limit intimal hyperplasia
- All devices incorporate proprietary patented technologies focused on maintaining consistent blood flow and minimizing trauma