Preservation Bio has created an ex vivo additive that blocks RHOA signaling, allowing platelets to be refrigerated for up to 14 days while retaining hemostatic function. The formulation integrates with existing blood‑bank collection and storage processes, reducing waste and improving inventory flexibility for hospitals, trauma centers, and blood services.
Funding
Funding not disclosed
Founders
Product
Problem
Platelet supplies are limited by a short 5‑day shelf life, leading to frequent shortages, high waste, and logistical challenges for hospitals and trauma centers. Cold storage of platelets causes functional degradation, making it difficult to maintain efficacy over longer periods.
Solution
Preservation Bio has developed an ex vivo additive formulation that enables platelets to be stored refrigerated for up to 14 days while retaining hemostatic function. The technology targets the molecular pathways responsible for cold‑induced storage lesions, specifically inhibiting RHOA activity to preserve platelet survival. By extending shelf life, the additive reduces waste, improves inventory flexibility, and supports more reliable delivery of platelet products to patients in need. The platform is positioned for clinical trials and aims to integrate with existing blood bank processing workflows, offering a scalable solution for transfusion services.
Target Audience
Primary customers are blood banks, hospital transfusion services, and regional blood centers that require reliable platelet inventories for trauma, oncology, and surgical patients.
Features
- Proprietary additive that blocks RHOA signaling to prevent cold‑storage lesions in platelets
- Validated preservation of platelet viability and hemostatic activity for up to 14 days under refrigeration
- Compatibility with standard blood bank collection, pooling, and storage equipment
- Pre‑clinical data published in peer‑reviewed journals demonstrating in‑vivo efficacy
- Designed for integration into current platelet processing pipelines without additional hardware