Pow.bio has developed a high-efficiency fermentation platform that decouples biomass growth from product production, addressing issues of contamination and genetic drift in biomanufacturing. This technology enables manufacturers to achieve 2-5 times more product output while reducing production costs by 40-70%.
Funding
$13.9M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
GNTVFounders
Product
Problem
Traditional biomanufacturing processes using large bioreactors often suffer from contamination issues, genetic drift, and inefficiencies in decoupling biomass growth from product production. These challenges lead to increased production costs and slower scaling for companies in the synthetic biology space.
Solution
Pow.Bio offers a high-efficiency fermentation platform that addresses the limitations of conventional biomanufacturing. Their continuous fermentation system decouples biomass growth and product production into separate, optimized stages. This approach minimizes contamination risks and genetic drift, while maximizing productivity. The platform utilizes a two-tank system where biomass is grown to optimal density in the first tank, then transferred to a second tank optimized for product generation. A filtration system harvests the product, removes waste, and recycles cells and media back into the production tank, creating a closed-loop, continuous process.
Target Audience
Pow.Bio's primary customers are companies in the synthetic biology, food protein, and biomanufacturing industries seeking to improve the efficiency and reduce the costs of their fermentation processes.
Features
- Decoupled growth and production stages for optimized biomanufacturing
- Continuous fermentation process for increased productivity and reduced downtime
- Integrated filtration system for product harvesting, waste removal, and resource recycling
- Demonstrated 2-5x increase in product output compared to traditional batch fermentation
- Potential to reduce commercial-scale biomanufacturing costs by 40-70%
- Ability to achieve 1 kg of material from a 2L reactor
- Suitable for various hosts, including Gram-negative bacteria, yeast, and Gram-positive bacteria