The startup develops specialized conduits for peripheral nerve injury repair that facilitate directional nerve regeneration without the need for autologous grafts. This technology reduces complications associated with donor site morbidity and neuroma formation, leading to improved recovery outcomes for patients.
Funding
$4.4M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Peripheral nerve injuries often require autologous nerve grafts, which involve harvesting a nerve from another part of the patient's body. This procedure can lead to donor site morbidity, neuroma formation, and prolonged surgical time, impacting patient recovery and increasing healthcare costs. Existing synthetic nerve repair solutions lack the optimized design to effectively promote directional nerve regeneration.
Solution
PolyNerve offers a resorbable nerve conduit designed to facilitate directional nerve regeneration without the need for autologous nerve grafts. The conduit's inner lumen features microgrooves with a topology optimized for nerve regeneration and cell therapy incorporation. This design enhances Schwann cell infiltration and guides the directional growth of regenerating axons. PolyNerve aims to reduce complications associated with donor site morbidity and neuroma formation, potentially improving patient recovery and reducing surgical time. The device is made from biodegradable, medically approved materials engineered to support nerve regeneration.
Target Audience
The primary target audience includes surgeons specializing in peripheral nerve repair, hospitals, and healthcare providers seeking to improve patient outcomes and reduce the costs associated with nerve injury treatment.
Features
- Microgrooved inner lumen optimized for directional nerve regeneration
- Biodegradable and biocompatible material composition
- Range of sizes to accommodate various nerve repair needs
- Designed to eliminate the need for autologous nerve grafts
- Reduced surgical time compared to autografting procedures
- Comparable efficacy to autologous nerve grafting in pre-clinical and clinical studies
- Flexible design providing protection while maintaining shape after bending