Phase Genomics develops ultra-long-range genome sequencing technology and computational tools that enable the assembly of complete and accurate genomes and metagenomes without the need for cultivation. This platform addresses the challenge of obtaining high-resolution genomic data, facilitating breakthroughs in agriculture, human health, and industrial biology.
Funding
$5.8M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Traditional genome sequencing and metagenomics methods often struggle to assemble complete and accurate genomes, especially for organisms that are difficult to cultivate or exist in complex microbial communities. This limitation hinders advancements in various fields, including agriculture, human health, and industrial biology, where high-resolution genomic data is crucial.
Solution
Phase Genomics provides a suite of ultra-long-range genome sequencing technologies and computational tools that enable researchers to assemble complete and accurate genomes and metagenomes without requiring cultivation. Their proximity ligation-based approach, including the Hi-C method, allows for rapid and cost-effective analysis of chromosome structure and organization. By mapping the physical proximity of DNA fragments, the platform reconstructs entire genomes, resolves haplotypes, and links mobile genetic elements to their hosts. This enables scientists to deconvolute complex metagenomic samples, identify chromosomal abnormalities, and study gene function and interactions with unprecedented resolution.
Target Audience
Phase Genomics serves scientists and researchers in academia, biopharmaceutical companies, and other organizations involved in plant and animal genomics, metagenomics, cytogenetics, and oncology.
Features
- Ultra-long-range sequencing technology for de novo genome assembly and scaffolding
- Proximity ligation (Hi-C) assays to capture chromosome structure and organization
- Metagenomic deconvolution to resolve complex microbial communities
- Computational tools for genome assembly, annotation, and comparative genomics
- Kits for plant and animal genomics, metagenomics, and cytogenetics
- Identification and characterization of chromosomal abnormalities
- Ability to resolve haplotypes and polyploidy