PeptiSystems manufactures fully automated synthesizers utilizing continuous flow technology for the production of peptide and oligonucleotide therapeutics, significantly reducing synthesis time from weeks to just 1-3 hours. Their systems provide real-time monitoring and consistent scalability, enabling efficient process development and large-scale manufacturing while improving yield and purity by up to 15%.
Funding
$4.1M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
SVFounders
Product
Problem
Traditional batch reactor methods for producing peptide and oligonucleotide therapeutics are time-consuming, often taking weeks to complete a synthesis. These methods can also suffer from inconsistent scalability, making process development and large-scale manufacturing challenging.
Solution
PeptiSystems provides a suite of fully automated synthesizers that leverage continuous flow technology to accelerate the production of peptide and oligonucleotide therapeutics. Their instruments reduce synthesis times to as little as 1-3 hours, a significant improvement over traditional methods. The systems offer linear scalability, enabling seamless transfer of synthesis parameters from process development to large-scale manufacturing. Real-time monitoring and graphical presentation of key parameters provide detailed insight into the synthesis process, while improving yield and purity.
Target Audience
The primary customers are biopharmaceutical and biotech companies involved in process development and large-scale GMP and non-GMP manufacturing of peptide and oligonucleotide therapeutics.
Features
- Fully automated synthesizers for peptide and oligonucleotide production
- Continuous flow technology for accelerated synthesis cycles (1-3 hours)
- Linear scale-up technology, maintaining synthesis parameters from process development to large-scale manufacturing (up to 5 mol)
- Real-time monitoring and graphical display of key synthesis parameters
- PeptiSoft management software designed for peptide and oligonucleotide chemistries
- Customizable synthesis scales, ranging from 0.1 mmol to 5 mol
- Options for R&D, process development, pre-clinical trials, and GMP commercial production
- Accurate pump system (+-0.05%) for precise liquid delivery