Path Fertility has developed SpermQT, a sperm analysis test that evaluates epigenetic biomarkers and DNA methylation to assess sperm functionality beyond traditional semen analysis. This technology addresses the common issue of unexplained infertility by providing critical insights into male fertility, enabling couples to make informed decisions about their fertility treatments.
Funding
Funding not disclosed

Founders
Product
Problem
Traditional semen analysis often fails to identify the underlying causes of unexplained infertility, as it primarily assesses sperm count and motility, overlooking critical functional aspects of sperm health. Couples undergoing fertility treatments may experience repeated failures due to undetected sperm-related issues that impact fertilization and early embryo development. This can lead to emotional distress and unnecessary expenses associated with ineffective treatments.
Solution
Path Fertility's SpermQT is a sperm analysis test that evaluates epigenetic biomarkers and DNA methylation patterns to provide a comprehensive assessment of sperm functionality. Unlike standard semen analysis, SpermQT measures the sperm's ability to find, bind, penetrate, and fertilize an egg, offering insights into the sperm's capacity to successfully complete the fertilization process. By identifying abnormalities in sperm function, SpermQT enables clinicians and patients to make informed decisions about selecting the most appropriate fertility treatment, potentially avoiding unsuccessful and costly procedures. The test results provide a deeper understanding of male fertility, allowing for personalized treatment plans that address specific sperm-related issues. SpermQT aims to improve the chances of successful conception by providing a more complete picture of sperm health beyond traditional metrics.
Target Audience
The primary target audience includes couples experiencing unexplained infertility, fertility clinics seeking advanced diagnostic tools, and andrologists looking to provide comprehensive male fertility assessments.
Features
- Epigenetic biomarker analysis to assess sperm functionality beyond basic semen parameters
- Evaluation of DNA methylation patterns to identify potential issues with sperm's ability to fertilize an egg
- Comprehensive report detailing sperm's ability to find, bind, penetrate, and fertilize an egg
- At-home sample collection kit for convenient and non-invasive sample submission
- Results delivered within two weeks of sample receipt
- Actionable insights to guide fertility treatment decisions and personalize treatment plans